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Insulin signaling

Unveiling the mechanism of calcitriol in treating type 2 diabetes mellitus: A combined network pharmacology and in vitro approach targeting ERS-related pathways

Fanqiang Zeng, Yimei Liao, Jianping Jiang, Chengjian Zhao, Shuihua Peng, Huijie Zhang, Hui Zou, Shudan Tan, Liya Qiao, Fan Liu, Juan Huo, Zhigang Yan, Yongli Xu

published 16 Apr 2026

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Methionine restriction provides sex-specific protection against high-fat diet-induced adiposity, peripheral insulin resistance, and neuroinflammation in FGF21-dependent and independent manners in mice

Hannah Lail, Rowan Lawrence, Filipe Pinheiro, Emily Price, Desiree Wanders

published 10 Mar 2026

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Kisspeptin improves local ovarian insulin resistance in PCOS by modulating the PI3K/AKT/GLUT4 signaling pathway

Na Sun, Pingping Sun, Lilan Sun, Ping Sun, Dandan Qi, Huagang Ma

published 02 Feb 2026

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Mechanistic study of plastic monomers in gestational diabetes mellitus: A network toxicology and molecular docking approach

Yingying Feng, Tingting Huang

published 29 Dec 2025

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Mapping the microRNA-mediated crosstalk between insulin resistance and Alzheimer’s disease: A computational genomic insight

Tehniat Faraz Ahmed, Affan Ahmed, Zeba Haque, Muhammad Bilal Azmi, Jawwad Us Salam, Farina Hanif

published 12 Dec 2025

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Novel insights into neuropathy: The impact of prolonged hyperglycemia on long non-coding RNA expression

Kamila Zglejc-Waszak, Jan Paweł Jastrzebski, Joanna Wojtkiewicz, Zenon Pidsudko, Judyta Karolina Juranek

published 27 Oct 2025

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A disproportionality analysis of insulin glargine in the overall population and in pregnant women using the FDA adverse event reporting system (FAERS) database

Shaozhi Liu, Jun Xu, Zhongwen Yuan, Zhengrong Mei, Shengying Shi, Jinjin Yin, Yanhong Deng

published 25 Sep 2025

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Effects of Conocarpus lancifolius and crocin on superoxide dismutase and protein kinase B genes and protein expressions in diabetic rats

Mohamed Lotfy, Abdallah Khalaf, Faisal AlBarghouthy, Abdulla Alhashmi, Hesham Adam, Abdulla Almesmari, Biduth Kundu, Taoufik Ksiksi

published 26 Jun 2025

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Functional profiling of synthetic camel milk-derived peptides with implication in glucose transport and diabetes

Irfa Anwar, Farheen Badrealam Khan, Bincy Baby, Priya Antony, Priti Mudgil, Chee-Yuen Gan, Sajid Maqsood, Ranjit Vijayan, Khalid Muhammad, Mohammed Akli Ayoub

published 28 Mar 2025

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Epigenome-wide methylation analysis shows phosphonoethylamine alleviates aberrant DNA methylation in NASH caused by Pcyt2 deficiency

Sophie Grapentine, Prasoon Agarwal, Vernon W. Dolinsky, Marica Bakovic

published 28 Mar 2025

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Elevated ambient temperature reduces fat storage through the FoxO-mediated insulin signaling pathway

Tucker Hopkins, Cole Ragsdale, Jin Seo

published 26 Feb 2025

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Bovine milk consumption affects the transcriptome of porcine adipose stem cells: Do exosomes play any role?

Katherine Swanson, Jimmy Bell, David Hendrix, Duo Jiang, Michelle Kutzler, Brandon Batty, Melanie Hanlon, Massimo Bionaz

published 20 Dec 2024

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In vivo treatment with a non-aromatizable androgen rapidly alters the ovarian transcriptome of previtellogenic secondary growth coho salmon (Onchorhynchus kisutch)

Christopher Monson, Giles Goetz, Kristy Forsgren, Penny Swanson, Graham Young

published 09 Oct 2024

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