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Immunoblotting

Development of a floxed Gabbr2 gene allows for widespread conditional disruption of GABBR2 and recapitulates the phenotype of germline Gabbr2 knockout mice

Julie Rose Hens, Stacey Brown, Pawel Licznerski, Jacqueline Suarez, Elizabeth Jonas, John J. Wysolmerski

published 15 Dec 2025

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Potential phosphorylation of Liprin-α1 at threonine 701 regulates integrin-mediated cell motility

Martina Ramella, Daniele Brambilla, Sara Surini, Diletta Tonoli, Lucrezia Maria Ribolla, Ivan de Curtis

published 01 Dec 2025

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Identification of cCMP- and cUMP-binding proteins using cCMP and cUMP coupled to agarose and biotin matrices

Sabine Wolter, Martin Neumann, Theresa Koenig, Tina Hagedorn, Frank Schwede, Andreas Pich, Roland Seifert

published 14 Oct 2025

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Clarification of fibrin generation and degradation reaction processes of clot-fibrinolysis waveform in hemorrhagic disorders

Tomoko Matsumoto, Nukumi Tujii, Daiki Shimomura, Aya Kouno, Takeshi Suzuki, Sho Shinohara, Nobuo Arai, Hiroshi Kurono, Osamu Kumano, Mikio Kamioka

published 18 Aug 2025

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Calcium-dependent pathway as a primary cause of hypoxic RGC damage in monkey retinal explants

Emi Nakajima, Momoko Otsugu-Kobayashi, Takatoshi Uchida, Kana Orihara, Thomas R. Shearer, Mitsuyoshi Azuma

published 11 Jul 2025

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SNAI2 cooperates with MEK1/2 and HDACs to suppress BIM- and BMF-dependent apoptosis in TERT promoter mutant cancers

Amol Tandon, Josh Lewis Stern

published 25 Jun 2025

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Titration-WB: A methodology for accurate quantitative protein determination overcoming reproducibility errors

Alice Maestri, Ewa Ehrenborg, Olivera Werngren, Maria Olin, Carolina E. Hagberg, Matteo Pedrelli, Paolo Parini

published 12 Jun 2025

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The tumor suppressor FAT1 controls YAP/TAZ protein degradation and tumor cell proliferation through E3 ligase MIB2

Rui Li, Boris Strilic, Young-June Jin, Jingchen Shao, Yundong Peng, Lei Wang, Qi Quan, Zhiyong Wang, Johannes Graumann, J. Silvio Gutkind, Nina Wettschureck, Stefan Offermanns

published 06 Jun 2025

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Zinc finger protein 184 prevents α-synuclein preformed fibril-mediated neurodegeneration through the interleukin enhancer binding factor 3-microRNA-7 pathway

Jihye Kim, Soojeong Park, Jee-Ho Lee, Ji-Yeong Lee, Joo-Ho Shin

published 07 May 2025

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Tie-2 regulates endothelial morphological responses to shear stress by FOXO1-triggered autophagy

Mana Ghanbarpour Houshangi, Keisuke Shirakura, Dietmar Vestweber

published 05 May 2025

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Allopurinol attenuates development of Porphyromonas gingivalis LPS-induced cardiomyopathy in mice

Akinaka Morii, Ichiro Matsuo, Kenji Suita, Yoshiki Ohnuki, Misao Ishikawa, Aiko Ito, Go Miyamoto, Mariko Abe, Takao Mitsubayashi, Yasumasa Mototani, Megumi Nariyama, Ren Matsubara, Yoshio Hayakawa, Yasuharu Amitani, Kazuhiro Gomi, Takatoshi Nagano, Satoshi Okumura

published 03 Apr 2025

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Intracellular accumulation of free cholesterol in macrophages triggers a PARP1 response to DNA damage and PARP1 impairs lipopolysaccharide-induced inflammatory response

Kenneth K.Y. Ting, Hisham M. Ibrahim, Nitya Gulati, Yufeng Wang, Jonathan V. Rocheleau, Myron I. Cybulsky

published 05 Mar 2025

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Zika virus modulates arthropod histone methylation for its survival in mosquito cells

Telvin Harrell, Swarnendu Basak, Hameeda Sultana, Girish Neelakanta

published 13 Feb 2025

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