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Hypercapnia

Active expiration reduces hypercapnia in lung failure – results of the prospective interventional ActiveEx study and development of a prototype device for automated application

Denis Witham, Julius Valentin Kunz, Ann-Christin Krebs, Karoline Brückner, Roland Körner, Mareen Pigorsch, Kai-Uwe Eckardt, Paul Uwe Thamsen, Philipp Enghard, Julija Peter

published 16 Oct 2025

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Lower neurovascular coupling response despite higher cerebral blood flow at rest in apolipoprotein ɛ4 positive adults

Andrew G. Pearson, Kathleen B. Miller, Adam T. Corkery, Nicole A. Loggie, Anna J. Howery, Leonardo A. Rivera-Rivera, Oliver Wieben, Kevin M. Johnson, Sterling C. Johnson, Jill N. Barnes

published 03 Dec 2024

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Suspected intracranial hypertension in COVID-19 patients with severe respiratory failure

Marco Carbonara, Erica Ferrari, Tatiana Birg, Veronica Punzi, Francesca Bichi, Beatrice Lazzari, Valentina Palmaverdi, Nicola Bottino, Fabrizio Ortolano, Tommaso Zoerle, Giorgio Conte, Nino Stocchetti, Elisa R. Zanier, The UOC Terapia Intensiva Presidio Temporaneo Fiera Milano investigators group

published 19 Sep 2024

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High-Flow Nasal Cannula Oxygen Therapy versus Non-Invasive Ventilation in patients at very high risk for extubating failure: A systematic review of randomized controlled trials

Ziyad F. Al Nufaiei, Raid M. Al Zhranei

published 03 Apr 2024

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Cool head-out water immersion does not alter cerebrovascular reactivity to hypercapnia despite elevated middle cerebral artery blood velocity: A pilot study

Morgan L. Worley, Emma L. Reed, Nathan Klaes, Zachary J. Schlader, Blair D. Johnson

published 13 Mar 2024

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Association between the first 24 hours PaCO₂ and all-cause mortality of patients suffering from sepsis-associated encephalopathy after ICU admission: A retrospective study

Honglian Luo, Gang Li, Bingxin Yang, Xinlei Huang, Yan Chen, Wei Shen

published 24 Oct 2023

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Effects of chronic mild hyperoxia on retinal and choroidal blood flow and retinal function in the DBA/2J mouse model of glaucoma

Eric R. Muir, Saurav B. Chandra, Divya Narayanan, Vincent Zhang, Ike Zhang, Zhao Jiang, Jeffrey W. Kiel, Timothy Q. Duong

published 25 Mar 2022

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Diabetic mice have retinal and choroidal blood flow deficits and electroretinogram deficits with impaired responses to hypercapnia

Eric R. Muir, Divya Narayanan, Saurav B. Chandra, Nikolay P. Akimov, Jeong-Hyeon Sohn, Evan Meyer, René C. Rentería, Timothy Q. Duong

published 09 Dec 2021

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Lung-protective properties of expiratory flow-initiated pressure-controlled inverse ratio ventilation: A randomised controlled trial

Go Hirabayashi, Minami Saito, Sachiko Terayama, Yuki Akihisa, Koichi Maruyama, Tomio Andoh

published 17 Dec 2020

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Non-invasive ventilation with pursed lips breathing mode for patients with COPD and hypercapnic respiratory failure: A retrospective analysis

Christoph Jünger, Maja Reimann, Lenka Krabbe, Karoline I. Gaede, Christoph Lange, Christian Herzmann, Stephan Rüller

published 21 Sep 2020

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Brain interstitial pH changes in the subacute phase of hypoxic-ischemic encephalopathy in newborn pigs

Gábor Remzső, János Németh, Viktória Varga, Viktória Kovács, Valéria Tóth-Szűki, Kai Kaila, Juha Voipio, Ferenc Domoki

published 29 May 2020

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Nocturnal hypercapnia with daytime normocapnia in patients with advanced pulmonary arterial hypertension awaiting lung transplantation

Yoshinari Nakatsuka, Toyofumi Chen-Yoshikawa, Hideyuki Kinoshita, Akihiro Aoyama, Hiroyasu Kubo, Kimihiko Murase, Satoshi Hamada, Hirofumi Takeyama, Takuma Minami, Naomi Takahashi, Kiminobu Tanizawa, Tomohiro Handa, Toyohiro Hirai, Hiroshi Date, Kazuo Chin

published 15 Apr 2020

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Cerebrovascular reactivity assessment with O₂-CO₂ exchange ratio under brief breath hold challenge

Suk-tak Chan, Karleyton C. Evans, Tian-yue Song, Juliette Selb, Andre van der Kouwe, Bruce R. Rosen, Yong-ping Zheng, Andrew Ahn, Kenneth K. Kwong

published 24 Mar 2020

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