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Hydrolases

Biodegradation of polyethylene terephthalate microplastics by Paenibacillus naphthalenovorans PETKKU2: Response surface optimization and genomic evidence for an alternative degradation mechanism

Aophat Choonut, Nantharat Wongfaed, Auraiwan Poolpol, Sophon Boonlue, Kitirote Wantala, Onruthai Pinyakong, Pensri Plangklang, Alissara Reungsang

published 04 Feb 2026

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Melatonin alleviates chronic intermittent hypoxia-induced gastric mucosal injury via attenuation of oxidative stress and JNK-mediated apoptotic signaling in rats

Hong L. Ji, Hua L. Yu, Jia F. Luo, Xin R. Li, Cheng X. Nie, Tie J. Liu, Huan H. Jiang, Cong H. Liu, Jia B. Zhang, Xin H. Yuan, Xiao F. Song, Yue D. Li, Yanlei Ge, Ai S. Fu

published 13 Jan 2026

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Phytochemical characterization, total phenolic and flavonoid content, antioxidant capacity, enzymatic profiling, and cytotoxicity of Bidens pilosa and Croton sp. from Colombia for applications in skin health

Patricia Quintero-Rincón, Karina Caballero-Gallardo, Elkin Galeano, Oscar Flórez-Acosta

published 09 Jan 2026

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Comprehensive transcriptome and metabolome analysis to exploration the effects of TCs on GCs lipid metabolism at goose pre-ovulatory follicle

Jisi Ma, Wenqiang Sun, Xin Yuan, Hongyu Long, Hui Shen, Chunying Liu, Xiang Gan

published 09 Jan 2026

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FtsZ phosphorylation modulates tail-core binding to tune cell division in Bacillus subtilis

William J. Mallard, Vincent V. Pham

published 29 Dec 2025

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How much genetic information in RNA form can be protected by a CCMV virus-like particle?

Ana Luisa Duran Meza, Sophie-Christine Porak, Abigail Chapman, Charles M. Knobler, William M. Gelbart

published 10 Dec 2025

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Low level of plasma DNase is associated with worse clinical outcome in testicular germ cell tumor patients and exogeneous DNase I improves cisplatin treatment efficacy

Michal Mego, Barbora Vlkova, Katarina Kalavska, Michal Pastorek, Zuzana Cierna, Zuzana Sestakova, Miroslav Chovanec, Natalia Udvorkova, Lucia Kucerova, Peter Celec

published 04 Dec 2025

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Synergistic enhancement of AAV gene delivery in 2D cells and 3D organoids using polybrene and hydroxychloroquine

Hyeon-Jin Na, Yongbo Shin, Seung-Hyun Kim, Seung Pil Jang, Myung Jin Son, Yong Min Choi, Hyeon Gyeol Jeon, Ok-Seon Kwon, Kyung-Sook Chung

published 14 Nov 2025

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Pathogenic rickettsiae encode a secreted lipase that facilitates intracytosolic colonization in host cells

Mohammad Sadik, Imran Moin, Saif Ullah, Andrew C. Krusenstjerna, Mathilde Gonin, Erin D. Goley, M. Sayeedur Rahman, Oliver H. Voss

published 08 Oct 2025

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Integrated analysis of ARHGAP6 potential function and prognostic value in acute myeloid leukemia

Debin Yang, Yuanzhe Li, Ping Ma, Fankai Xiao

published 07 Oct 2025

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Predicting chromatin conformation contact maps

Alan Min, Jacob Schreiber, Anshul Kundaje, William S. Noble

published 29 Sep 2025

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IGF-1 downregulates matrix metalloproteinase 8 to promote plaque stability: Evidence from myeloid cell-specific MMP8 in atherosclerosis

Patricia Snarski, Sergiy Sukhanov, Tadashi Yoshida, Svitlana Danchuk, Andrew Gross, Fareed Sindi, Vikara Rivera-Lopez, Patrice Delafontaine, Yusuke Higashi

published 24 Sep 2025

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Resolution of physics and deep learning-based protein engineering filters: A case study with a lipase for industrial substrate hydrolysis

Spencer Gardiner, Peter Dollinger, Filip Kovacic, Jörg Pietruszka, Daniel H. Ess, Karl-Erich Jaeger, Gunnar F. Schröder, Dennis Della Corte

published 12 Sep 2025

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