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Huntington disease

Genome-Wide Histone Acetylation Is Altered in a Transgenic Mouse Model of Huntington's Disease

Karen N. McFarland, Sudeshna Das, [ ... ], Jang-Ho J. Cha

Aggregation of PolyQ Proteins Is Increased upon Yeast Aging and Affected by Sir2 and Hsf1: Novel Quantitative Biochemical and Microscopic Assays

Aviv Cohen, Liron Ross, Iftach Nachman, Shoshana Bar-Nun

SlimPLS: A Method for Feature Selection in Gene Expression-Based Disease Classification

Michael Gutkin, Ron Shamir, Gideon Dror

When Cytokinin, a Plant Hormone, Meets the Adenosine A_2A Receptor: A Novel Neuroprotectant and Lead for Treating Neurodegenerative Disorders?

Yi-Chao Lee, Ying-Chen Yang, [ ... ], Nai-Kuei Huang

The Q175 Mouse Model of Huntington’s Disease Shows Gene Dosage- and Age-Related Decline in Circadian Rhythms of Activity and Sleep

Dawn H. Loh, Takashi Kudo, [ ... ], Christopher S. Colwell

Bifunctional Anti-Huntingtin Proteasome-Directed Intrabodies Mediate Efficient Degradation of Mutant Huntingtin Exon 1 Protein Fragments

David C. Butler, Anne Messer

The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington’s Disease

Xianjun Dong, Junko Tsuji, [ ... ], Zhiping Weng

Ubiquilin-1 Overexpression Increases the Lifespan and Delays Accumulation of Huntingtin Aggregates in the R6/2 Mouse Model of Huntington's Disease

Nathaniel Safren, Amina El Ayadi, [ ... ], Mervyn J. Monteiro

Huntingtin’s Function in Axonal Transport Is Conserved in Drosophila melanogaster

Diana Zala, Maria-Victoria Hinckelmann, Frédéric Saudou

Alloimmunisation to Donor Antigens and Immune Rejection Following Foetal Neural Grafts to the Brain in Patients with Huntington's Disease

Pierre Krystkowiak, Véronique Gaura, [ ... ], Anne-Catherine Bachoud-Lévi

The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington’s Disease Mice

Haiqun Jia, Ying Wang, [ ... ], Elizabeth A. Thomas

Genetic Knock-Down of HDAC7 Does Not Ameliorate Disease Pathogenesis in the R6/2 Mouse Model of Huntington's Disease

Caroline L. Benn, Rachel Butler, [ ... ], Gillian P. Bates

Atg4b-Dependent Autophagic Flux Alleviates Huntington’s Disease Progression

Catia C. Proenca, Natacha Stoehr, [ ... ], Ivan Galimberti

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