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Huntington disease

Characterizing differences in retinal and choroidal microvasculature and structure in individuals with Huntington’s Disease compared to healthy controls: A cross-sectional prospective study

Suzanna Joseph, Cason B. Robbins, Alice Haystead, Angela Hemesath, Ariana Allen, Anita Kundu, Justin P. Ma, Burton L. Scott, Kathryn P. L. Moore, Rupesh Agrawal, Vithiya Gunasan, Sandra S. Stinnett, Dilraj S. Grewal, Sharon Fekrat

published 30 Jan 2024

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Is retina affected in Huntington’s disease? Is optical coherence tomography a good biomarker?

Pavel Dusek, Ales Kopal, Michaela Brichova, Jan Roth, Olga Ulmanova, Jiri Klempir, Jana Lizrova Preiningerova

published 24 Feb 2023

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Reduction in PA28αβ activation in HD mouse brain correlates to increased mHTT aggregation in cell models

Karlijne W. Geijtenbeek, Jolien Janzen, Aleksandra E. Bury, Alicia Sanz-Sanz, Ron A. Hoebe, Marie K. Bondulich, Gillian P. Bates, Eric A. J. Reits, Sabine Schipper-Krom

published 27 Dec 2022

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Caspase-2 mRNA levels are not elevated in mild cognitive impairment, Alzheimer’s disease, Huntington’s disease, or Lewy Body dementia

Chris Hlynialuk, Lisa Kemper, Kailee Leinonen-Wright, Ronald C. Petersen, Karen Ashe, Benjamin Smith

published 21 Sep 2022

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Huntington’s disease phenotypes are improved via mTORC1 modulation by small molecule therapy

Sophie St-Cyr, Daniel D. Child, Emilie Giaime, Alicia R. Smith, Christine J. Pascua, Seung Hahm, Eddine Saiah, Beverly L. Davidson

published 29 Aug 2022

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Global Rhes knockout in the Q175 Huntington’s disease mouse model

Taneli Heikkinen, Timo Bragge, Juha Kuosmanen, Teija Parkkari, Sanna Gustafsson, Mei Kwan, Jose Beltran, Afshin Ghavami, Srinivasa Subramaniam, Neelam Shahani, Uri Nimrod Ramírez-Jarquín, Larry Park, Ignacio Muñoz-Sanjuán, Deanna M. Marchionini

published 14 Oct 2021

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Cognitive decline in Huntington’s disease in the Digitalized Arithmetic Task (DAT)

Marine Lunven, Jennifer Hamet Bagnou, Katia Youssov, Alexis Gabadinho, Rafika Fliss, Justine Montillot, Etienne Audureau, Blanche Bapst, Graça Morgado, Ralf Reilmann, Robin Schubert, Monica Busse, David Craufurd, Renaud Massart, Anne Rosser, Anne-Catherine Bachoud-Lévi

published 23 Aug 2021

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The relationship between non-motor features and weight-loss in the premanifest stage of Huntington’s disease

Wasiq Khan, Sundus Alusi, Hissam Tawfik, Abir Hussain

published 01 Jul 2021

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Hybrid 2-[¹⁸F] FDG PET/MRI in premanifest Huntington’s disease gene-expansion carriers: The significance of partial volume correction

Marie N. N. Hellem, Tua Vinther-Jensen, Lasse Anderberg, Esben Budtz-Jørgensen, Lena E. Hjermind, Vibeke Andrée Larsen, Jørgen E. Nielsen, Ian Law

published 11 Jun 2021

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Computer-aided identification of degenerative neuromuscular diseases based on gait dynamics and ensemble decision tree classifiers

Luay Fraiwan, Omnia Hassanin

published 04 Jun 2021

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Iron activates microglia and directly stimulates indoleamine-2,3-dioxygenase activity in the N171-82Q mouse model of Huntington’s disease

David W. Donley, Marley Realing, Jason P. Gigley, Jonathan H. Fox

published 14 May 2021

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Abnormally abrupt transitions from sleep-to-wake in Huntington’s disease sheep (Ovis aries) are revealed by automated analysis of sleep/wake transition dynamics

William T. Schneider, Szilvia Vas, Alister U. Nicol, A. Jennifer Morton

published 13 May 2021

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System biology and bioinformatics pipeline to identify comorbidities risk association: Neurodegenerative disorder case study

Utpala Nanda Chowdhury, Shamim Ahmad, M. Babul Islam, Salem A. Alyami, Julian M. W. Quinn, Valsamma Eapen, Mohammad Ali Moni

published 06 May 2021

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