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Human genomics

Genetic diversity in the IZUMO1-JUNO protein-receptor pair involved in human reproduction

Jessica Allingham, Wely B. Floriano

Protocol for assessment of the efficiency of CRISPR/Cas RNP delivery to different types of target cells

Marina A. Tyumentseva, Aleksandr I. Tyumentsev, Vasiliy G. Akimkin

Nanopore sequencing of SARS-CoV-2: Comparison of short and long PCR-tiling amplicon protocols

Broňa Brejová, Kristína Boršová, [ ... ], Jozef Nosek

The limits of personalization in precision medicine: Polygenic risk scores and racial categorization in a precision breast cancer screening trial

Jennifer Elyse James, Leslie Riddle, Barbara Ann Koenig, Galen Joseph

Differential expression of transposable elements in the medaka melanoma model

Frederik Helmprobst, Susanne Kneitz, [ ... ], Manfred Schartl

Exogene: A performant workflow for detecting viral integrations from paired-end next-generation sequencing data

Zachary Stephens, Daniel O’Brien, [ ... ], Jean-Pierre Kocher

Predicting drug sensitivity of cancer cells based on DNA methylation levels

Sofia P. Miranda, Fernanda A. Baião, Julia L. Fleck, Stephen R. Piccolo

A virtual deliberative public engagement study on heritable genome editing among South Africans: Study protocol

Donrich Thaldar, Beverley Townsend, [ ... ], Siddharthiya Pillay

Standardization of DNA amount for bisulfite conversion for analyzing the methylation status of LINE-1 in lung cancer

Duong Anh Thuy Pham, Son Duc Le, [ ... ], Lan Thi Thuong Vo

Distributed hybrid-indexing of compressed pan-genomes for scalable and fast sequence alignment

Altti Ilari Maarala, Ossi Arasalo, [ ... ], Keijo Heljanko

Unified platform for genetic and serological detection of COVID-19 with single-molecule technology

Noa Furth, Shay Shilo, [ ... ], Efrat Shema

Identification of novel and rare variants associated with handgrip strength using whole genome sequence data from the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program

Chloé Sarnowski, Han Chen, [ ... ], from the NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium

Genome-wide binding analysis of 195 DNA binding proteins reveals “reservoir” promoters and human specific SVA-repeat family regulation

Michael J. Smallegan, Soraya Shehata, [ ... ], John L. Rinn

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