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HL60 cells

Genomic discovery of EF-24 targets unveils antitumorigenic mechanisms in leukemia cells

Ajeet P. Singh, Noah Wax, James Duncan, Ana S. Fernandes, Jonathan L. Jacobs

published 23 Sep 2025

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Modulation of cellular adhesion, contractility, and migration by MiuA: A comprehensive analysis of its biomechanical impact

Carsten Alexander Baltes, Friederike Nolle, Kathi Michèle Kaiser, Erbara Gjana, Kristin Sander, Karin Jacobs, Rhoda Joy Hawkins, Franziska Lautenschläger

published 05 Sep 2025

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Enhancing reproducibility in single cell research with biocytometry: An inter-laboratory study

Pavel Fikar, Laura Alvarez, Laura Berne, Martin Cienciala, Christopher Kan, Hynek Kasl, Mona Luo, Zuzana Novackova, Sheyla Ordonez, Zuzana Sramkova, Monika Holubova, Daniel Lysak, Lyndsay Avery, Andres A. Caro, Roslyn N. Crowder, Laura A. Diaz-Martinez, David W. Donley, Rebecca R. Giorno, Irene K. Guttilla Reed, Lori L. Hensley, Kristen C. Johnson, Audrey Y. Kim, Paul Kim, Adriana J. LaGier, Jamie J. Newman, Elizabeth Padilla-Crespo, Nathan S. Reyna, Nikolaos Tsotakos, Noha N. Al-Saadi, Tayler Appleton, Ana Arosemena-Pickett, Braden A. Bell, Grace Bing, Bre Bishop, Christa Forde, Michael J. Foster, Kassidy Gray, Bennett L. Hasley, Kennedy Johnson, Destiny J. Jones, Allison C. LaShall, Kennedy McGuire, Naomi McNaughton, Angelina M. Morgan, Lucas Norris, Landon A. Ossman, Paollette A. Rivera-Torres, Madeline E. Robison, Kathryn Thibodaux, Lescia Valmond, Daniel Georgiev

published 09 Dec 2024

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Vitamin K2 sensitizes the efficacy of venetoclax in acute myeloid leukemia by targeting the NOXA-MCL-1 pathway

Tetsuzo Tauchi, Shota Moriya, Seiichi Okabe, Hiromi Kazama, Keisuke Miyazawa, Naoharu Takano

published 25 Jul 2024

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Neutrophil-like cells derived from the HL-60 cell-line as a genetically-tractable model for neutrophil degranulation

Suhani B. Bhakta, Stefan M. Lundgren, Bethany N. Sesti, Barbara A. Flores, Emel Akdogan, Sean R. Collins, Frances Mercer

published 07 Feb 2024

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Yinzhihuang injection induces apoptosis and suppresses tumor growth in acute myeloid leukemia cells

Zhe Huang, Yunfu Shen, Xianming Fan, Qulian Guo, Wenzhe Ma

published 10 Oct 2023

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Inhibition of casein kinase 2 induces cell death in tyrosine kinase inhibitor resistant chronic myelogenous leukemia cells

Ondřej Mitrovský, Denisa Myslivcová, Tereza Macháčková-Lopotová, Adam Obr, Kamila Čermáková, Šárka Ransdorfová, Jana Březinová, Hana Klamová, Markéta Žáčková

published 04 May 2023

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NUC-7738 regulates β-catenin signalling resulting in reduced proliferation and self-renewal of AML cells

Akbar Muhammed Shahid, In Hwa Um, Mustafa Elshani, Ying Zhang, David James Harrison

published 15 Dec 2022

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A pyridinesulfonamide derivative FD268 suppresses cell proliferation and induces apoptosis via inhibiting PI3K pathway in acute myeloid leukemia

Yi Chen, Tianze Wu, Chengbin Yang, Mingzhu Lu, Zhenxia Chen, Mingli Deng, Yu Jia, Yongtai Yang, Xiaofeng Liu, Hongyan Wang, Yun Ling, Lei Lu, Yaming Zhou

published 22 Nov 2022

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Blockade of p38 MAPK overcomes AML stem cell line KG1a resistance to 5-Fluorouridine and the impact on miRNA profiling

Sabine Matou-Nasri, Maria Najdi, Nouran Abu AlSaud, Yazeid Alhaidan, Hamad Al-Eidi, Ghada Alatar, Deemah AlWadaani, Thadeo Trivilegio, Arwa AlSubait, Abeer AlTuwaijri, Manal Abudawood, Bader Almuzzaini

published 05 May 2022

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Examination of CD302 as a potential therapeutic target for acute myeloid leukemia

Tsun-Ho Lo, Edward Abadir, Robin E. Gasiorowski, Karieshma Kabani, Murari Ramesh, Daniel Orellana, Phillip D. Fromm, Fiona Kupresanin, Elizabeth Newman, Ilona Cunningham, Derek N. J. Hart, Pablo A. Silveira, Georgina J. Clark

published 10 May 2019

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Pyronaridine exerts potent cytotoxicity on human breast and hematological cancer cells through induction of apoptosis

Paulina J. Villanueva, Alberto Martinez, Sarah T. Baca, Rebecca E. DeJesus, Manuel Larragoity, Lisett Contreras, Denisse A. Gutierrez, Armando Varela-Ramirez, Renato J. Aguilera

published 05 Nov 2018

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The arginase inhibitor N^ω−hydroxy−nor−arginine (nor−NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target

King Pan Ng, Aditi Manjeri, Lin Ming Lee, Zhu En Chan, Chin Yee Tan, Qiancheng Darren Tan, A'Qilah Majeed, Kian Leong Lee, Charles Chuah, Toshio Suda, S. Tiong Ong

published 11 Oct 2018

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