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Hepatocytes

The PTP1B selective inhibitor MSI-1436 mitigates Tunicamycin-induced ER stress in human hepatocarcinoma cell line through XBP1 splicing modulation

Lynda Bourebaba, Sai Santosh Babu Komakula, [ ... ], Krzysztof Marycz

Mathematical models for biomarker calculation of drug-induced liver injury in humans and experimental models based on gadoxetate enhanced magnetic resonance imaging

Markus Karlsson, Christian Simonsson, [ ... ], Peter Lundberg

Age-dependent sex difference of non-alcoholic fatty liver disease in TSOD and db/db mice

Erdenetsogt Dungubat, Hiroyuki Kusano, [ ... ], Yoshihisa Takahashi

Characterization of a KDM5 small molecule inhibitor with antiviral activity against hepatitis B virus

Sarah A. Gilmore, Danny Tam, [ ... ], Becket Feierbach

The autophagic protein p62 is a target of reactive aldehydes in human and murine cholestatic liver disease

Colin T. Shearn, Aimee L. Anderson, [ ... ], Ronald J. Sokol

Novel AAV-mediated genome editing therapy improves health and survival in a mouse model of methylmalonic acidemia

Shengwen Zhang, Amy Bastille, [ ... ], B. Nelson Chau

Functionally impaired isoforms regulate TMPRSS6 proteolytic activity

Sébastien P. Dion, Antoine Désilets, Gabriel Lemieux, Richard Leduc

Cold-induced metabolic depression in cunner (Tautogolabrus adspersus): A multifaceted cellular event

Lucie Gerber, Courtney E. MacSween, James F. Staples, A. Kurt Gamperl

The influence of metformin transporter gene SLC22A1 and SLC47A1 variants on steady-state pharmacokinetics and glycemic response

Vitarani Dwi Ananda Ningrum, Ahmad Hamim Sadewa, [ ... ], Rohmatul Fajriyah

Species specific morphological alterations in liver tissue after biliary occlusion in rat and mouse: Similar but different

Beate Richter, Constanze Sänger, [ ... ], Uta Dahmen

Utilizing virtual experiments to increase understanding of discrepancies involving in vitro-to-in vivo predictions of hepatic clearance

Preethi Krishnan, Andrew K. Smith, [ ... ], C. Anthony Hunt

Slightly different metabolomic profiles are associated with high or low weight duck foie gras

Bara Lo, Nathalie Marty-Gasset, [ ... ], Herve Remignon

Nrf2 deficiency causes hepatocyte dedifferentiation and reduced albumin production in an experimental extrahepatic cholestasis model

Guo-Ying Wang, Veronica Garcia, [ ... ], Guoli Dai

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