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Helicases

The RNA helicase eIF4A as a novel target in insect cells to combat arboviral infections

Tanja Rehling, Kim Mentchen, Leonie Konopka, Wiebke Obermann, Friedemann Weber, Patrick Schmerer, Marc F. Schetelig, Arnold Grünweller, Irina Häcker, Francesca Magari

published 06 Apr 2026

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A comprehensive in silico investigation into the pathogenic SNPs in the RTEL1 gene and their biological consequences

Rifah Rownak Tanshee, Zimam Mahmud, A. H. M. Nurun Nabi, Mohammad Sayem

published 06 Sep 2024

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Replication stress response in fission yeast differentially depends on maintaining proper levels of Srs2 helicase and Rrp1, Rrp2 DNA translocases

Gabriela Baranowska, Dorota Misiorna, Wojciech Białek, Karol Kramarz, Dorota Dziadkowiec

published 21 Jun 2024

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In vitro biological evaluation and in silico insights into the antiviral activity of standardized olive leaves extract against SARS-CoV-2

Taghreed A. Majrashi, Mahmoud A. El Hassab, Sara H. Mahmoud, Ahmed Mostafa, Engy A. Wahsh, Eslam B. Elkaeed, Fatma E. Hassan, Wagdy M. Eldehna, Shimaa M. Abdelgawad

published 25 Apr 2024

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Biochemical properties of naturally occurring human bloom helicase variants

Rachel R. Cueny, Sameer Varma, Kristina H. Schmidt, James L. Keck

published 02 Jun 2023

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X-ray crystal structure of the Escherichia coli RadD DNA repair protein bound to ADP reveals a novel zinc ribbon domain

Miguel A. Osorio Garcia, Kenneth A. Satyshur, Michael M. Cox, James L. Keck

published 28 Apr 2022

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Examination of the roles of a conserved motif in the PriA helicase in structure-specific DNA unwinding and processivity

Alexander T. Duckworth, Tricia A. Windgassen, James L. Keck

published 30 Jul 2021

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Structural characterisation of the Chaetomium thermophilum Chl1 helicase

Zuzana Hodáková, Andrea Nans, Simone Kunzelmann, Shahid Mehmood, Ian Taylor, Frank Uhlmann, Peter Cherepanov, Martin R. Singleton

published 10 May 2021

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Protection of the C. elegans germ cell genome depends on diverse DNA repair pathways during normal proliferation

Bettina Meier, Nadezda V. Volkova, Ye Hong, Simone Bertolini, Víctor González-Huici, Tsvetana Petrova, Simon Boulton, Peter J. Campbell, Moritz Gerstung, Anton Gartner

published 27 Apr 2021

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Mapping major SARS-CoV-2 drug targets and assessment of druggability using computational fragment screening: Identification of an allosteric small-molecule binding site on the Nsp13 helicase

Matthew R. Freidel, Roger S. Armen

published 17 Feb 2021

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Influence of light on the infection of Aureococcus anophagefferens CCMP 1984 by a “giant virus”

Eric R. Gann, P. Jackson Gainer, Todd B. Reynolds, Steven W. Wilhelm

published 03 Jan 2020

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Conformational flexibility of fork-remodeling helicase Rad5 shown by full-ensemble hybrid methods

Melissa S. Gildenberg, M. Todd Washington

published 18 Oct 2019

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Role of DEAD-box RNA helicase genes in the growth of Yersinia pseudotuberculosis IP32953 under cold, pH, osmotic, ethanol and oxidative stresses

Xiaojie Jiang, Riikka Keto-Timonen, Mikael Skurnik, Hannu Korkeala

published 09 Jul 2019

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