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Guide RNA

A system for site-specific integration of transgenes in mammalian cells

Xiuling Chi, Qi Zheng, Ruhong Jiang, Ruby Yanru Chen-Tsai, Ling-Jie Kong

published 25 Jul 2019

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Amplification-free long-read sequencing of TCF4 expanded trinucleotide repeats in Fuchs Endothelial Corneal Dystrophy

Eric D. Wieben, Ross A. Aleff, Shubham Basu, Vivekananda Sarangi, Brett Bowman, Ian J. McLaughlin, John R. Mills, Malinda L. Butz, Edward W. Highsmith, Cristiane M. Ida, Jenny M. Ekholm, Keith H. Baratz, Michael P. Fautsch

published 05 Jul 2019

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Protein features for assembly of the RNA editing helicase 2 subcomplex (REH2C) in Trypanosome holo-editosomes

Vikas Kumar, Pawan K. Doharey, Shelly Gulati, Joshua Meehan, Mary G. Martinez, Karrisa Hughes, Blaine H. M. Mooers, Jorge Cruz-Reyes

published 29 Apr 2019

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CD46 knock-out using CRISPR/Cas9 editing of hTERT immortalized human cells modulates complement activation

Matthias Wieser, Teresa Francisci, Daniel Lackner, Tilmann Buerckstuemmer, Kamilla Wasner, Wolf Eilenberg, Anton Stift, Markus Wahrmann, Georg A. Böhmig, Johannes Grillari, Regina Grillari-Voglauer

published 08 Apr 2019

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Development of CRISPR/Cas9-mediated gene disruption systems in Giardia lamblia

Zi-Qi Lin, Soo-Wah Gan, Szu-Yu Tung, Chun-Che Ho, Li-Hsin Su, Chin-Hung Sun

published 11 Mar 2019

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Edition of TFAM gene by CRISPR/Cas9 technology in bovine model

Vanessa Cristina de Oliveira, Gabriel Sassarão Alves Moreira, Fabiana Fernandes Bressan, Clésio Gomes Mariano Junior, Kelly Cristine Santos Roballo, Marine Charpentier, Jean-Paul Concordet, Flávio Vieira Meirelles, Carlos Eduardo Ambrósio

published 07 Mar 2019

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The Crohn’s disease associated SNP rs6651252 impacts MYC gene expression in human colonic epithelial cells

Stephen M. Matthews, Melanie A. Eshelman, Arthur S. Berg, Walter A. Koltun, Gregory S. Yochum

published 22 Feb 2019

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CRISPR-cas gene-editing as plausible treatment of neuromuscular and nucleotide-repeat-expansion diseases: A systematic review

Haris Babačić, Aditi Mehta, Olivia Merkel, Benedikt Schoser

published 22 Feb 2019

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Mouse models of GNAO1-associated movement disorder: Allele- and sex-specific differences in phenotypes

Huijie Feng, Casandra L. Larrivee, Elena Y. Demireva, Huirong Xie, Jeff R. Leipprandt, Richard R. Neubig

published 25 Jan 2019

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Agnostic detection of genomic alterations by holistic DNA structural interrogation

Ryan K. Shultzaberger, Rachel E. Abrams, Challise J. Sullivan, Anthony D. Schmitt, Thomas W. J. Thompson, John Dresios

published 29 Nov 2018

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Efficient CRISPR/Cas9-based genome editing and its application to conditional genetic analysis in Marchantia polymorpha

Shigeo S. Sugano, Ryuichi Nishihama, Makoto Shirakawa, Junpei Takagi, Yoriko Matsuda, Sakiko Ishida, Tomoo Shimada, Ikuko Hara-Nishimura, Keishi Osakabe, Takayuki Kohchi

published 31 Oct 2018

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Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays

Morito Kurata, Natalie K. Wolf, Walker S. Lahr, Madison T. Weg, Mitchell G. Kluesner, Samantha Lee, Kai Hui, Masano Shiraiwa, Beau R. Webber, Branden S. Moriarity

published 17 Sep 2018

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Efficient genome editing using tRNA promoter-driven CRISPR/Cas9 gRNA in Aspergillus niger

Letian Song, Jean-Paul Ouedraogo, Magdalena Kolbusz, Thi Truc Minh Nguyen, Adrian Tsang

published 24 Aug 2018

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