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Guide RNA

RNA-guided gene editing of the murine gammaherpesvirus 68 genome reduces infectious virus production

Hui-Chen Chang Foreman, Varvara Kirillov, [ ... ], Yue Zhang

Non-replicative phage particles delivering CRISPR-Cas9 to target major bla_CTX-M variants

Naiyaphat Nittayasut, Teerapong Yata, [ ... ], Pattrarat Chanchaithong

Enhancer polymorphisms at the IKZF1 susceptibility locus for acute lymphoblastic leukemia impact B-cell proliferation and differentiation in both Down syndrome and non-Down syndrome genetic backgrounds

Vincent U. Gant, Jacob J. Junco, [ ... ], Karen R. Rabin

Additive and Transcript-Specific Effects of KPAP1 and TbRND Activities on 3′ Non-Encoded Tail Characteristics and mRNA Stability in Trypanosoma brucei

Sara L. Zimmer, Sarah M. McEvoy, Sarita Menon, Laurie K. Read

Structure of the T. brucei kinetoplastid RNA editing substrate-binding complex core component, RESC5

Raul Salinas, Emily Cannistraci, Maria A. Schumacher

Toward an all-in-one recombinant adeno-associated virus vector for functionally ablating the prion gene using CRISPR-Cas technology

Claire Verkuyl, Ari Belotserkovsky, [ ... ], Gerold Schmitt-Ulms

Multiplexed CRISPR-mediated engineering of protein secretory pathway genes in the thermotolerant methylotrophic yeast Ogataea thermomethanolica

Worarat Kruasuwan, Aekkachai Puseenam, Sutipa Tanapongpipat, Niran Roongsawang

A simple validation and screening method for CRISPR/Cas9-mediated gene editing in mouse embryos to facilitate genetically modified mice production

Dawid Winiarczyk, Hossein Khodadadi, Paweł Leszczyński, Hiroaki Taniguchi

In vitro genome editing activity of Cas9 in somatic cells after random and transposon-based genomic Cas9 integration

Jenny-Helena Söllner, Hendrik Johannes Sake, [ ... ], Björn Petersen

Lung development, repair and cancer: A study on the role of MMP20 gene in adenocarcinoma

Pooi Ling Mok, Arun Neela Kumar Anandasayanam, [ ... ], Badr Alzahrani

Cardiac RNase Z edited via CRISPR-Cas9 drives heart hypertrophy in Drosophila

Ekaterina Migunova, Saathvika Rajamani, [ ... ], Edward B. Dubrovsky

A bacterial dual positive and negative selection system for dCas9 activity

Shaun Spisak, Brett O’Brien, Marc Ostermeier

Fusion of histone variants to Cas9 suppresses non-homologous end joining

Tomoko Kato-Inui, Gou Takahashi, Terumi Ono, Yuichiro Miyaoka

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