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GTPase signaling

Novel Split-Luciferase-Based Genetically Encoded Biosensors for Noninvasive Visualization of Rho GTPases

Weibing Leng, Xiaohui Pang, [ ... ], Feng Bi

A Rac1/Cdc42 GTPase-Specific Small Molecule Inhibitor Suppresses Growth of Primary Human Prostate Cancer Xenografts and Prolongs Survival in Mice

Karin Zins, Trevor Lucas, [ ... ], Seyedhossein Aharinejad

The Temporal Order of Genetic and Pathway Alterations in Tumorigenesis

Moritz Gerstung, Nicholas Eriksson, [ ... ], Niko Beerenwinkel

p21-Activated Kinase (PAK) Regulates Cytoskeletal Reorganization and Directional Migration in Human Neutrophils

Asako Itakura, Joseph E. Aslan, [ ... ], Owen J. T. McCarty

Activation of G Proteins by Guanine Nucleotide Exchange Factors Relies on GTPase Activity

Rob J. Stanley, Geraint M. H. Thomas

Serine-71 Phosphorylation of Rac1 Modulates Downstream Signaling

Janett Schwarz, Julia Proff, [ ... ], Ralf Gerhard

RabGEF1/Rabex-5 Regulates TrkA-Mediated Neurite Outgrowth and NMDA-Induced Signaling Activation in NGF-Differentiated PC12 Cells

See-Ying Tam, Jennifer N. Lilla, [ ... ], Mindy Tsai

Topological and Functional Properties of the Small GTPases Protein Interaction Network

Anna Delprato

Small Molecule Inhibitors of the Candida albicans Budded-to-Hyphal Transition Act through Multiple Signaling Pathways

John Midkiff, Nathan Borochoff-Porte, Dylan White, Douglas I. Johnson

An Integrated Model of the Transcriptome of HER2-Positive Breast Cancer

Krishna R. Kalari, Brian M. Necela, [ ... ], Edith A. Perez

Blood-Based Gene Expression Profiles Models for Classification of Subsyndromal Symptomatic Depression and Major Depressive Disorder

Zhenghui Yi, Zezhi Li, [ ... ], Yiru Fang

Evidence for Immune Response, Axonal Dysfunction and Reduced Endocytosis in the Substantia Nigra in Early Stage Parkinson’s Disease

Anke A. Dijkstra, Angela Ingrassia, [ ... ], Wilma D. J. van de Berg

Structures of SRP54 and SRP19, the Two Proteins that Organize the Ribonucleic Core of the Signal Recognition Particle from Pyrococcus furiosus

Pascal F. Egea, Johanna Napetschnig, Peter Walter, Robert M. Stroud

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