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Glucagon

Liver-specific glucagon dysfunction promotes PP-cell hyperplasia and formation of glucagon and PP double-positive cells

Yuko Nakagawa, Takuro Horii, Ayako Fukunaka, Takashi Sato, Zhehao Zhang, Masaki Kobayashi, Tadahiro Kitamura, Yoshitaka Hayashi, Takashi Nishimura, Izuho Hatada, Yoshio Fujitani

published 23 Sep 2025

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Effect of exercise on Fibroblast Growth Factor 21 levels in healthy males and females

Matthew Peterson, Kathleen A. Richardson, LesLee Funderburk

published 29 May 2025

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Itaconate potentiates hepatic gluconeogenesis through NRF2 induction

Marwa O. El-Derany, Sadeesh K. Ramakrishnan, Yingjie Li, Kathryn Buscher, Christina A. Jarad, Megan L. Schaller, Marc Cantwell, Thomas M. Vigil, Ryan A. Frieler, Peter Sajjakulnukit, Costas A. Lyssiotis, Richard M. Mortensen, Yatrik M. Shah

published 05 May 2025

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Analysis of aggregation profile of glucagon using SEC-HPLC and FFF-MALS methods

Zhongli Bao, Ya-Chi Cheng, Mary Ziping Luo, Jack Yongfeng Zhang

published 21 May 2024

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Semaglutide combined with empagliflozin vs. monotherapy for non-alcoholic fatty liver disease in type 2 diabetes: Study protocol for a randomized clinical trial

Yu-Hao Lin, Zhi-Jun Zhang, Jin-Qing Zhong, Zhi-Yi Wang, Yi-Ting Peng, Yan-Mei Lin, Huo-Ping Zhang, Jian-Qing Tian

published 03 May 2024

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Repressing miR-23a promotes the transdifferentiation of pancreatic α cells to β cells via negatively regulating the expression of SDF-1α

Hongmei Lang, Ning Lin, Xiaorong Chen, Jie Xiang, Xingping Zhang, Chao Kang

published 22 Mar 2024

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The entero-endocrine response following a mixed-meal tolerance test with a non-nutritive pre-load in participants with pre-diabetes and type 2 diabetes: A crossover randomized controlled trial proof of concept study

Mirthe Muilwijk, Joline W. J. Beulens, Lenka Groeneveld, Femke Rutters, Marieke T. Blom, Valeria Agamennone, Tim van den Broek, Bart J. F. Keijser, Femke Hoevenaars

published 25 Aug 2023

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DYRK1A inhibitors leucettines and TGF-β inhibitor additively stimulate insulin production in beta cells, organoids, and isolated mouse islets

Barbara Pucelik, Agata Barzowska, Anna Czarna

published 17 May 2023

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Assessment of innate immune response modulating impurities in glucagon for injection

Qingxia Han, Zhongli Bao, Mary Ziping Luo, Jack Yongfeng Zhang

published 21 Nov 2022

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Differential effects of RYGB surgery and best medical treatment for obesity-diabetes on intestinal and islet adaptations in obese-diabetic ZDSD rats

Ananyaa Sridhar, Dawood Khan, Mahmoud Abdelaal, Jessie A. Elliott, Violetta Naughton, Peter R. Flatt, Carel W. Le Roux, Neil G. Docherty, Charlotte R. Moffett

published 22 Sep 2022

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Comprehensive evaluation of patterns of hypoglycemia unawareness (HUA) and glycemic variability (GV) in patients with fibrocalculous pancreatic diabetes (FCPD): A cross-sectional study from South India

Riddhi Dasgupta, Felix K. Jebasingh, Shajith Anoop, Santhya Seenivasan, Mathews Edatharayil Kurian, Flory Christina, Gracy Varghese, Pamela Christudoss, K. U. Lijesh, Deepu David, Sudipta Dhar Chowdhury, Thomas V. Paul, Nihal Thomas

published 12 Jul 2022

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Preclinical evaluation of a protracted GLP-1/glucagon receptor co-agonist: Translational difficulties and pitfalls

Lotte Simonsen, Jesper Lau, Thomas Kruse, Tingqing Guo, Jim McGuire, Jacob Fuglsbjerg Jeppesen, Kristoffer Niss, Per Sauerberg, Kirsten Raun, Charlotta Dornonville de la Cour

published 04 Mar 2022

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Beneficial impact of Ac3IV, an AVP analogue acting specifically at V1a and V1b receptors, on diabetes islet morphology and transdifferentiation of alpha- and beta-cells

Shruti Mohan, Ryan Lafferty, Neil Tanday, Peter R. Flatt, R. Charlotte Moffett, Nigel Irwin

published 20 Dec 2021

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