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Glial cells

Inhibition of SUR1-TRPM4 attenuates astrocyte swelling and reactivity under oxygen-glucose deprivation/reoxygenation

Yuanyuan Zhao, Narawut Pakaprot, Rujapope Sutiwisesak, Unchalee Vattarakorn, Sompol Tapechum

published 24 Jun 2026

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The mTOR/Akt pathway is involved in regulating astrocyte growth and GLT-1 expression during cerebral ischemia-reperfusion

Qiuling Li, Yiwen Yu, Huan Deng, Biao Li, Hao Zhao, Dong Lei, Mi Li, Shansha Xie, Jingmei Yu, Yuping Zhao, Shubin Yin, YiFei Ji

published 12 Jun 2026

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Protocatechuic acid prevents obesity caused by long-chain saturated fatty acid-induced inflammation in mouse microglia via inhibition of the NF-κB pathway

Ken-yu Hironao, Shoma Fujino, Yusei Johta, Kevin Odongo, Hitoshi Ashida, Yoko Yamashita

published 01 Jun 2026

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Long-term rapamycin treatment suppresses IL-17-producing gamma delta T cells and blunts neuroinflammation in aging

Clement Torrent, Caterina Gagliardi, Nina Fülle, Ignazio Antignano, Maria Eugenia Bernis, Miriam Stork, Daniele Bano, Melania Capasso, Lily Keane

published 28 May 2026

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Retinal macrophage-like cell activation and ganglion cell layer thinning are associated with disability and MRI lesion burden in multiple sclerosis

Francesco Pichi, Yanny Perez Jimenez, Matteo Belletti, Alia Alsuwaidi, Fatema Alawadhi, Gina Lee, Piergiorgio Neri, Victoria Mifsud, Anu Jacob, Beatrice Benedetti, Ester Carreño

published 22 May 2026

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Single-cell multiomics data analysis of potential receptors and therapeutic drugs for epilepsy patients comorbid with depression

Guiqin Bai, Xuerong Zhou, Cheng Xiong, Xi Kang, Ruiqi Huang, Dazhang Bai, Peilin Zhao, Tao Peng, Cheer Muer, Guohui Jiang, Shushan Zhang

published 22 Apr 2026

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Single-cell RNA sequencing identifies microglial state changes associated with iTBS after ischemia–reperfusion injury

Yingying Huang, Yining Zhao, Xingyu Zhang, Xia Bi

published 20 Apr 2026

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Differential regulation of p62-ubiquitin conjugates in neurons versus astrocytes during cellular stress

David K. Sidibe, Erin M. Smith, Maeve L. Spivey, Maria C. Vogel, Sandra Maday

published 20 Apr 2026

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Dysregulated lactate metabolism synergizes with ALS genetic risk factors to accelerate motor decline

Shweta Tendulkar, Tong Wu, Amy Strickland, Amber R. Hackett, Yurie Sato-Yamada, Xianrong Mao, Yo Sasaki, Jeffrey Milbrandt, A. Joseph Bloom, Aaron DiAntonio

published 17 Apr 2026

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Gastrodin alleviates neuronal damage in epileptic cell models by targeting P2RY12 to inhibit microglial hyperactivation

Aiyuan Cai, Zilong Li, Ran Liu, Hailong Huang, Ping Liu, Ruizhong Zhang, Jing Xiao, Yuanhong Lin, Qingpeng Hu, Haixia Wu

published 17 Apr 2026

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Role of donor nerves in supercharge end-to-side nerve transfer: A rat model study of varying injury severity

Masaru Munemori, Akira Kodama, Nobuo Adachi

published 01 Apr 2026

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5-HT1B receptor agonists promote Schwann cell myelination

Yuka Kobayashi-Ujiie, Keiko Hiraki-Kamon, Shuji Wakatsuki, Toshiyuki Araki

published 27 Mar 2026

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Hippocampal transcriptome profiling reveals status epilepticus-induced early changes in gene expression mainly implicating in neuroinflammation and immune responses linked to microglial dysfunction

Hui-Ling Tang, Yu Min, Yue-Sheng Long

published 20 Mar 2026

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