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Genomic signal processing

Identification of novel and rare variants associated with handgrip strength using whole genome sequence data from the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program

Chloé Sarnowski, Han Chen, Mary L. Biggs, Sylvia Wassertheil-Smoller, Jan Bressler, Marguerite R. Irvin, Kathleen A. Ryan, David Karasik, Donna K. Arnett, L. Adrienne Cupples, David W. Fardo, Stephanie M. Gogarten, Benjamin D. Heavner, Deepti Jain, Hyun Min Kang, Charles Kooperberg, Arch G. Mainous, Braxton D. Mitchell, Alanna C. Morrison, Jeffrey R. O’Connell, Bruce M. Psaty, Kenneth Rice, Albert V. Smith, Ramachandran S. Vasan, B. Gwen Windham, Douglas P. Kiel, Joanne M. Murabito, Kathryn L. Lunetta, on behalf of the TOPMed Longevity and Healthy Aging Working Group , from the NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium

published 02 Jul 2021

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Profiling DNA break sites and transcriptional changes in response to contextual fear learning

Ryan T. Stott, Oleg Kritsky, Li-Huei Tsai

published 01 Jul 2021

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Machine-learning a virus assembly fitness landscape

Pierre-Philippe Dechant, Yang-Hui He

published 05 May 2021

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New evidence confirming the CD genomic constitutions of the tetraploid Avena species in the section Pachycarpa Baum

Honghai Yan, Zichao Ren, Di Deng, Kehan Yang, Chuang Yang, Pingping Zhou, Charlene P. Wight, Changzhong Ren, Yuanying Peng

published 08 Jan 2021

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Deletion of Mediator 1 suppresses TGFβ signaling leading to changes in epidermal lineages and regeneration

Yuko Oda, Thai Nguyen, Akiko Hata, Mark B. Meyer, J. Wesley Pike, Daniel D. Bikle

published 28 Aug 2020

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Predicting gene regulatory regions with a convolutional neural network for processing double-strand genome sequence information

Koh Onimaru, Osamu Nishimura, Shigehiro Kuraku

published 23 Jul 2020

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A novel drug repurposing approach for non-small cell lung cancer using deep learning

Bingrui Li, Chan Dai, Lijun Wang, Hailong Deng, Yingying Li, Zheng Guan, Haihong Ni

published 11 Jun 2020

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A population-specific low-frequency variant of SLC22A12 (p.W258*) explains nearby genome-wide association signals for serum uric acid concentrations among Koreans

Sun-Wha Im, Jeesoo Chae, Ho-Young Son, Belong Cho, Jong-Il Kim, Jin-Ho Park

published 09 Apr 2020

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Genomic landscape of the signals of positive natural selection in populations of Northern Eurasia: A view from Northern Russia

Andrey V. Khrunin, Gennady V. Khvorykh, Alexei N. Fedorov, Svetlana A. Limborska

published 05 Feb 2020

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Non-gradient and genotype-dependent patterns of RSV gene expression

Felipe-Andrés Piedra, Xueting Qiu, Michael N. Teng, Vasanthi Avadhanula, Annette A. Machado, Do-Kyun Kim, James Hixson, Justin Bahl, Pedro A. Piedra

published 10 Jan 2020

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Functional models in genome-wide selection

Ernandes Guedes Moura, Andrezza Kellen Alves Pamplona, Marcio Balestre

published 23 Oct 2019

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Novel and known signals of selection for fat deposition in domestic sheep breeds from Africa and Eurasia

Salvatore Mastrangelo, Hussain Bahbahani, Bianca Moioli, Abulgasim Ahbara, Mohammed Al Abri, Faisal Almathen, Anne da Silva, Ibrahim Belabdi, Baldassare Portolano, Joram M. Mwacharo, Olivier Hanotte, Fabio Pilla, Elena Ciani

published 14 Jun 2019

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Identification of factors associated with duplicate rate in ChIP-seq data

Shulan Tian, Shuxia Peng, Michael Kalmbach, Krutika S. Gaonkar, Aditya Bhagwate, Wei Ding, Jeanette Eckel-Passow, Huihuang Yan, Susan L. Slager

published 03 Apr 2019

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