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Genome engineering

The VAChTY49N mutation provides insecticide-resistance but perturbs evoked cholinergic neurotransmission in Drosophila

Samuel W. Vernon, Jim Goodchild, Richard A. Baines

Efficient genome editing using tRNA promoter-driven CRISPR/Cas9 gRNA in Aspergillus niger

Letian Song, Jean-Paul Ouedraogo, [ ... ], Adrian Tsang

CRISPR/Cas-based customization of pooled CRISPR libraries

Jiyeon Kweon, Da-eun Kim, An-Hee Jang, Yongsub Kim

A CRISPR screen identifies MAPK7 as a target for combination with MEK inhibition in KRAS mutant NSCLC

Nicholas Dompe, Christiaan Klijn, [ ... ], David Stokoe

Reemergence of human plague in Yunnan, China in 2016

Liyuan Shi, Guirong Yang, [ ... ], Peng Wang

DMSO increases efficiency of genome editing at two non-coding loci

George Stratigopoulos, Maria Caterina De Rosa, [ ... ], Claudia A. Doege

Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation

Michael J. Thomenius, Jennifer Totman, [ ... ], P. Ann Boriack-Sjodin

Uncoupling of sgRNAs from their associated barcodes during PCR amplification of combinatorial CRISPR screens

Mudra Hegde, Christine Strand, Ruth E. Hanna, John G. Doench

An optimized electroporation approach for efficient CRISPR/Cas9 genome editing in murine zygotes

Simon E. Tröder, Lena K. Ebert, [ ... ], Branko Zevnik

One step generation of customizable gRNA vectors for multiplex CRISPR approaches through string assembly gRNA cloning (STAgR)

Christopher T. Breunig, Tamara Durovic, [ ... ], Stefan H. Stricker

Genome comparison of different Zymomonas mobilis strains provides insights on conservation of the evolution

Chen Chen, Linfeng Wu, [ ... ], Xuemei Tan

Bifidobacteria isolated from vaginal and gut microbiomes are indistinguishable by comparative genomics

Aline C. Freitas, Janet E. Hill

Chromatin accessibility is associated with CRISPR-Cas9 efficiency in the zebrafish (Danio rerio)

Meri I. E. Uusi-Mäkelä, Harlan R. Barker, [ ... ], Mika Rämet

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