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Genetics of disease

Using machine learning to predict and analyze complex trait diseases: Lessons from a simple abstract model

Eden Maimon, Ori Bondi, John Moult, Ron Unger

published 23 Feb 2026

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Evidence for genetic correlation between appendix and inflammatory bowel disease: A bidirectional Mendelian randomization study

Dan Liu, Wanyue Dan, Bin Yan, Lihua Peng, Fei Pan

published 11 Feb 2026

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Genetics to Improve Outcomes in Schizophrenia (GENios): A within-case molecular genetic study protocol

Sophie E. Smart, Eilidh Fenner, Rhys Humphreys, Amanda Wells, Katherine Fender, Catherine Bresner, Giulia Trauzzi, Isabella R. Willcocks, Sophie E. Legge, Antonio F. Pardiñas, Elliott Rees, Valentina Escott-Price, Peter Holmans, Michael C. O’Donovan, Michael J. Owen, James T. R. Walters

published 05 Feb 2026

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Genetic insights into number of long-term conditions and their relationship with lifespan

Youngjune Bhak, Bruce Guthrie, Albert Tenesa

published 30 Jan 2026

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Genetic predisposition to elevated BMI and adult asthma phenotypes in a Japanese population

Yohei Yatagai, Hisayuki Oshima, Yu Abe, Haruna Kitazawa, Hironori Masuko, Takashi Naito, Takefumi Saito, Tomomitsu Hirota, Mayumi Tamari, Emiko Noguchi, Tohru Sakamoto, Nobuyuki Hizawa

published 29 Jan 2026

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Integrative multi-omics analyses identify key genes and elucidate bidirectional regulatory mechanisms in thyroid dysfunction

Yilang Hu, Hong Hu, Lijun Xu, Xuzheng Tang, Chongyu Wang, Zhengyi Lian, Chenyu Xie, Zhiwan Xie, Qingqing Wang

published 22 Jan 2026

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Egg quality characteristics of South African Potchefstroom Koekoek and commercial Lohmann brown layer chickens: A comparative study

Victoria Rankotsane Hlokoe, Thobela Louis Tyasi, Vusi Gordon Mbazima

published 12 Jan 2026

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Phenome-wide screening of the putative causal determinants of bipolar affective disorder using genetic data

Bin Hu, Qi Zhou, Hao Wu, Dejiang Yang, Chongyu Xiong, Xiaowei Zhang

published 02 Jan 2026

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To test or not to test? Study protocol for a best-worst scaling to understand decision-making and preferences for genetic testing in moderate-risk individuals

Carina Oedingen, Nicolle Hua, Karen V. MacDonald, Julien Marcadier, Renee Perrier, Lindsay Tuer, Brenda McInnes, Francois Bernier, Deborah A. Marshall

published 29 Dec 2025

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Gender difference in self-reported empathy: Effects of task instructions and exposure to gender essentialism primes

Namitha Rajasekhar, Anna Redly, Shevantika Nanda, Gillian R. Brown

published 12 Dec 2025

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Exploring the genetic frontier: Unraveling ANRIL, PAI-1, and HNF1α in stroke progression

Abdullah Hamadi, Rashid Mir, Osama M. Al-Amer, Mohammed Alasseiri, Gasim Dobie, Imadeldin Elfaki, Waseem AlZamzami, Sael Alatawi, Atif Abdulwahab A. Oyouni, Mohammad A. Alanazi, Saravanan Muthupandian

published 11 Dec 2025

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Using pre-training and interaction modeling for ancestry-specific disease prediction using multiomics data from the UK Biobank

Thomas Le Menestrel, Erin Craig, Robert Tibshirani, Trevor Hastie, Manuel Rivas

published 01 Dec 2025

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A multilayered genetic structure analysis between inflammatory bowel disease and bone density/osteoporosis

Mengting Qin, Xinhong Liu, Qinghua Luo, Ruyun Cai

published 20 Nov 2025

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