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Genetics

Bidirectional phenotypic transition in macrophages influences triple-negative breast cancer cell immune evasive patterns and response to chemotherapies in a co-culture spheroid model

Chen Cheng, Brett A. McGregor, Junguk Hur, Colin K. Combs

published 14 Aug 2026

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Evaluating genetic diversity differences within a likelihood framework

David C. Nickle

published 14 Aug 2026

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Good DNA- and sufficient RNA integrity in formalin-free paraffin-embedded tissues

Maarten Niemantsverdriet, Natalie Methorst, Sanne Yvet Hoek, Ageeth Knol, Agnes Marije Hoogland

published 14 Aug 2026

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Environmental enrichment attenuates chronic stress–induced disruptions in the gut microbiota, intestinal barrier, and brain

Seung Ju Kang, Hyeong Ju Nam, Min Kyung Song

published 14 Aug 2026

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Sex differences in the effects of shift work-like schedules on gut microbiome and intestinal barrier in relation to stroke survival

Ella Barnum, Jonathan L. Turck, Karienn A. Souza, Kathiresh Kumar Mani, Rachel Pilla, Amutha Selvamani, Farida Sohrabji, David J. Earnest

published 14 Aug 2026

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Phenotypic variation and diversity assessment in maize landraces

Longxue Wei, Lianghai Guo, Dongbo Zhao, Jianjun Guo, Yirong Jin, Jiansheng Gao, Huini Cui, Liang Zhang, Peng Liu, Zhihui Guo

published 14 Aug 2026

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Prediction of potential biomarkers and therapeutic targets in HIV viremic patients using immune-related circRNA-miRNA-mRNA regulatory networks

Negin Faraji, Leila Rouhi, Azam Bolhassani, Behnam Hasannejad-asl, Kazem Baesi, Ladan Abbasian

published 14 Aug 2026

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A chemically optimized, GalNAc-conjugated siRNA targeting HSD17B13 demonstrates efficacy in a human 3D organoid model of MASH, showcasing an alternative to animal testing

Qin Meng, Xujia Wang, Yuxuan Zhang, Sudeep Pushpakom, Jun Yang, Hui Feng, Mu Wang

published 14 Aug 2026

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MyD88 restricts dysbiosis-mediated inflammation in filaggrin deficient skin

Meng-Jen Wu, Advaitaa Ravipati, Yu Wang, Laine E. Feller, Alyssa Chu, Rishi Damarla, Zhiyang Li, Lam C. Tsoi, Ryleigh Griffin, Peng Hou, Hai Liang, Raif Geha, Julia A. Segre, Heidi H. Kong, Johann E. Gudjonsson, Nathan K. Archer

published 14 Aug 2026

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Genetic variability and population structure within the Anopheles tessellatus complex (Theobald, 1901) in Indonesia using ITS2 nuclear and COI, COII mitochondrial sequences

Anis Nurwidayati, Hari Purwanto, Raden Roro Upiek Ngesti Wibawaning Astuti, Yudhi Ratna Nugraheni, Lulus Susanti, Yuyun Srikandi, Budi Setiadi Daryono, Triwibowo Ambar Garjito, Sylvie Manguin

published 14 Aug 2026

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Development of KASP molecular markers and construction of fingerprinting for cowpea (Vigna unguiculata (L.) Walp.) based on ddRAD-Seq

Juan Xiang, Zhuoling Zhong, Chengming Zhang, Min He, Kun Cai, Lanping Gu, Li Xu, Shilin Su, Yi Zou, Jie Li, Kehao Cui, Huimin Qiu, Bengang Xian, Shaohong Fu, Ling Chen, Xiaowei Liu

published 14 Aug 2026

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Study protocol: Effect of inulin supplementation on gut microbiota in patients with oral lichen planus — A double-blind, randomised, placebo-controlled parallel-group trial

Koki Nambu, Naoki Kaneko, Shiho Yokomizo, Hu Chen, Lijing Yan, Wang Shiyao, Ryusei Shizuma, Eiji Iwata, Yukiko Ohyama, Shohei Akagawa, Soichiro Ibaragi, Shintaro Kawano, Masafumi Moriyama

published 13 Aug 2026

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Regulatory effects of smoking cessation on the cellular microenvironment and differentially expressed genes in precancerous lesions of pulmonary nodules in mice based on single-cell RNA sequencing and immune repertoire-sequencing

Xintong Wang, Fang Tang, Jiayu Qin, Tiquan Xiao, Liwei Shi, Shujun Zhang, Chunli Che

published 13 Aug 2026

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