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Genetically modified animals

Globus Pallidus Externus Neurons Expressing parvalbumin Interconnect the Subthalamic Nucleus and Striatal Interneurons

Arpiar Saunders, Kee Wui Huang, Bernardo Luis Sabatini

published 23 Feb 2016

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β-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development

Ahmed M. Abdellatif, Hisashi Oishi, Takahiro Itagaki, Yunshin Jung, Hossam H. Shawki, Yukari Okita, Yoshikazu Hasegawa, Hiroyuki Suzuki, Salah E. El-Morsy, Mesbah A. El-Sayed, Mahmoud B. Shoaib, Fumihiro Sugiyama, Satoru Takahashi

published 22 Feb 2016

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Plaque Size Is Decreased but M1 Macrophage Polarization and Rupture Related Metalloproteinase Expression Are Maintained after Deleting T-Bet in ApoE Null Mice

Aikaterini Tsaousi, Elaine M. Hayes, Karina Di Gregoli, Andrew R. Bond, Laura Bevan, Anita C. Thomas, Andrew C. Newby

published 17 Feb 2016

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Generation and Characterisation of a Pax8-CreER^T2 Transgenic Line and a Slc22a6-CreER^T2 Knock-In Line for Inducible and Specific Genetic Manipulation of Renal Tubular Epithelial Cells

Judit Espana-Agusti, Xiangang Zou, Kim Wong, Beiyuan Fu, Fengtang Yang, David A. Tuveson, David J. Adams, Athena Matakidou

published 11 Feb 2016

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Conditional Expression of the Androgen Receptor Increases Susceptibility of Bladder Cancer in Mice

Daniel T. Johnson, Erika Hooker, Richard Luong, Eun-Jeong Yu, Yongfeng He, Mark L. Gonzalgo, Zijie Sun

published 10 Feb 2016

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Sequestration of Vascular Endothelial Growth Factor (VEGF) Induces Late Restrictive Lung Disease

Minna M. Wieck, Ryan G. Spurrier, Daniel E. Levin, Salvador Garcia Mojica, Michael J. Hiatt, Raghava Reddy, Xiaogang Hou, Sonia Navarro, Jooeun Lee, Amber Lundin, Barbara Driscoll, Tracy C. Grikscheit

published 10 Feb 2016

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Characterization of Behavioral, Neuropathological, Brain Metabolic and Key Molecular Changes in zQ175 Knock-In Mouse Model of Huntington’s Disease

Qi Peng, Bin Wu, Mali Jiang, Jing Jin, Zhipeng Hou, Jennifer Zheng, Jiangyang Zhang, Wenzhen Duan

published 09 Feb 2016

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AKT1^E17K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer

Donatella Malanga, Stefania Belmonte, Fabiana Colelli, Marzia Scarfò, Carmela De Marco, Duarte Mendes Oliveira, Teresa Mirante, Caterina Camastra, Monica Gagliardi, Antonia Rizzuto, Chiara Mignogna, Orlando Paciello, Serenella Papparella, Henrik Fagman, Giuseppe Viglietto

published 09 Feb 2016

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Establishment of Leptin-Responsive Cell Lines from Adult Mouse Hypothalamus

Hiroshi Iwakura, Katsuko Dote, Mika Bando, Hiroyuki Koyama, Kiminori Hosoda, Kenji Kangawa, Kazuwa Nakao

published 05 Feb 2016

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Transgenic Expression of the Formin Protein Fhod3 Selectively in the Embryonic Heart: Role of Actin-Binding Activity of Fhod3 and Its Sarcomeric Localization during Myofibrillogenesis

Noriko Fujimoto, Meikun Kan-o, Tomoki Ushijima, Yohko Kage, Ryuji Tominaga, Hideki Sumimoto, Ryu Takeya

published 05 Feb 2016

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Conditional Deletion of Fgfr1 in the Proximal and Distal Tubule Identifies Distinct Roles in Phosphate and Calcium Transport

Xiaobin Han, Jiancheng Yang, Linqiang Li, Jinsong Huang, Gwendalyn King, L. Darryl Quarles

published 03 Feb 2016

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Activation of Dll4/Notch Signaling and Hypoxia-Inducible Factor-1 Alpha Facilitates Lymphangiogenesis in Lacrimal Glands in Dry Eye

Ji Hwan Min, Chul Hee Lee, Yong Woo Ji, Areum Yeo, Hyemi Noh, Insil Song, Eung Kweon Kim, Hyung Keun Lee

published 01 Feb 2016

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Prader-Willi Critical Region, a Non-Translated, Imprinted Central Regulator of Bone Mass: Possible Role in Skeletal Abnormalities in Prader-Willi Syndrome

Ee-Cheng Khor, Bruce Fanshawe, Yue Qi, Sergei Zolotukhin, Rishikesh N. Kulkarni, Ronaldo F. Enriquez, Louise Purtell, Nicola J. Lee, Natalie K. Wee, Peter I. Croucher, Lesley Campbell, Herbert Herzog, Paul A. Baldock

published 29 Jan 2016

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