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Genetically modified animals

Extracellular Release of CD11b by TLR9 Stimulation in Macrophages

Dongbum Kim, Te Ha Kim, Guang Wu, Byoung Kwon Park, Ji-Hee Ha, Yong-Sung Kim, Keunwook Lee, Younghee Lee, Hyung-Joo Kwon

published 08 Mar 2016

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Tissue-Specific Suppression of Thyroid Hormone Signaling in Various Mouse Models of Aging

W. Edward Visser, Cíntia R. Bombardieri, Chantal Zevenbergen, Sander Barnhoorn, Alexandre Ottaviani, Ingrid van der Pluijm, Renata Brandt, Ellen Kaptein, Ramona van Heerebeek, Hans van Toor, George A. Garinis, Robin P. Peeters, Marco Medici, Willy van Ham, Wilbert P. Vermeij, Monique C. de Waard, Ronald R. de Krijger, Anita Boelen, Joan Kwakkel, John J. Kopchick, Edward O. List, Joost P. M. Melis, Veerle M. Darras, Martijn E. T. Dollé, Gijsbertus T. J. van der Horst, Jan H. J. Hoeijmakers, Theo J. Visser

published 08 Mar 2016

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Deletion of the Toll-Like Receptor 5 Gene Per Se Does Not Determine the Gut Microbiome Profile That Induces Metabolic Syndrome: Environment Trumps Genotype

Wei Zhang, Riley Hartmann, Hein Min Tun, Charles O. Elson, Ehsan Khafipour, W. Timothy Garvey

published 07 Mar 2016

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Chronic Psychological Stress Disrupted the Composition of the Murine Colonic Microbiota and Accelerated a Murine Model of Inflammatory Bowel Disease

Yohei Watanabe, Sohei Arase, Noriko Nagaoka, Mitsuhisa Kawai, Satoshi Matsumoto

published 07 Mar 2016

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Conditional Inducible Triple-Transgenic Mouse Model for Rapid Real-Time Detection of HCV NS3/4A Protease Activity

Min Yao, Xin Lu, Yingfeng Lei, Jing Yang, Haiwei Zhao, Qinghua Qiao, Peijun Han, Zhikai Xu, Wen Yin

published 04 Mar 2016

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Contrasting Roles of Islet Resident Immunoregulatory Macrophages and Dendritic Cells in Experimental Autoimmune Type 1 Diabetes

Thomas B. Thornley, Krishna A. Agarwal, Periklis Kyriazis, Lingzhi Ma, Vaja Chipashvili, Jonathan E. Aker, Sarantis Korniotis, Eva Csizmadia, Terry B. Strom, Maria Koulmanda

published 04 Mar 2016

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Synaptosomal Mitochondrial Dysfunction in 5xFAD Mouse Model of Alzheimer's Disease

Lu Wang, Lan Guo, Lin Lu, Huili Sun, Muming Shao, Simon J. Beck, Lin Li, Janani Ramachandran, Yifeng Du, Heng Du

published 04 Mar 2016

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Deletion of Rac1GTPase in the Myeloid Lineage Protects against Inflammation-Mediated Kidney Injury in Mice

Miki Nagase, Hidetake Kurihara, Atsu Aiba, Morag J. Young, Tatsuo Sakai

published 03 Mar 2016

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PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma

Alok R. Singh, Shweta Joshi, Muamera Zulcic, Michael Alcaraz, Joseph R. Garlich, Guillermo A. Morales, Yoon J. Cho, Lei Bao, Michael L. Levy, Robert Newbury, Denise Malicki, Karen Messer, John Crawford, Donald L. Durden

published 03 Mar 2016

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Foxn1 Transcription Factor Regulates Wound Healing of Skin through Promoting Epithelial-Mesenchymal Transition

Barbara Gawronska-Kozak, Anna Grabowska, Anna Kur-Piotrowska, Marta Kopcewicz

published 03 Mar 2016

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Primary Ovarian Insufficiency Induced by Fanconi Anemia E Mutation in a Mouse Model

Chun Fu, Khurshida Begum, Paul A. Overbeek

published 03 Mar 2016

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Gtsf1l and Gtsf2 Are Specifically Expressed in Gonocytes and Spermatids but Are Not Essential for Spermatogenesis

Noriaki Takemoto, Takuji Yoshimura, Satsuki Miyazaki, Fumi Tashiro, Jun-ichi Miyazaki

published 01 Mar 2016

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Regional Fluctuation in the Functional Consequence of LINE-1 Insertion in the Mitf Gene: The Black Spotting Phenotype Arisen from the Mitfmi-bw Mouse Lacking Melanocytes

Kazuhisa Takeda, Hiroki Hozumi, Koji Ohba, Hiroaki Yamamoto, Shigeki Shibahara

published 01 Mar 2016

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