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Genetically modified animals

Interleukin-6 Deficiency Does Not Affect Motor Neuron Disease Caused by Superoxide Dismutase 1 Mutation

Yongmei Han, Barry Ripley, Satoshi Serada, Tetsuji Naka, Minoru Fujimoto

published 12 Apr 2016

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Granzyme A Is Expressed in Mouse Lungs during Mycobacterium tuberculosis Infection but Does Not Contribute to Protection In Vivo

Santiago Uranga, Dessislava Marinova, Carlos Martin, Julián Pardo, Nacho Aguilo

published 07 Apr 2016

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4-1BB Signaling in Conventional T Cells Drives IL-2 Production That Overcomes CD4⁺CD25⁺FoxP3⁺ T Regulatory Cell Suppression

Hampartsoum B. Barsoumian, Esma S. Yolcu, Haval Shirwan

published 06 Apr 2016

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Mice with a Mutation in the Mdm2 Gene That Interferes with MDM2/Ribosomal Protein Binding Develop a Defect in Erythropoiesis

Takuya Kamio, Bai-wei Gu, Timothy S. Olson, Yanping Zhang, Philip J. Mason, Monica Bessler

published 04 Apr 2016

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Critical Endothelial Regulation by LRP5 during Retinal Vascular Development

Wei Huang, Qing Li, Mahmood Amiry-Moghaddam, Madoka Hokama, Sylvia H. Sardi, Masashi Nagao, Matthew L. Warman, Bjorn R. Olsen

published 31 Mar 2016

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The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington’s Disease Mice

Haiqun Jia, Ying Wang, Charles D. Morris, Vincent Jacques, Joel M. Gottesfeld, James R. Rusche, Elizabeth A. Thomas

published 31 Mar 2016

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Adiponectin at Physiologically Relevant Concentrations Enhances the Vasorelaxative Effect of Acetylcholine via Cav-1/AdipoR-1 Signaling

Yunhui Du, Rui Li, Wayne Bigond Lau, Jianli Zhao, Bernard Lopez, Theodore A. Christopher, Xin-Liang Ma, Yajing Wang

published 29 Mar 2016

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Ezetimibe Promotes Brush Border Membrane-to-Lumen Cholesterol Efflux in the Small Intestine

Takanari Nakano, Ikuo Inoue, Yasuhiro Takenaka, Hiraku Ono, Shigehiro Katayama, Takuya Awata, Takayuki Murakoshi

published 29 Mar 2016

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TCR and IL-7 Signaling Are Altered in the Absence of Functional GTPase of the Immune Associated Nucleotide Binding Protein 5 (GIMAP5)

Xi-Lin Chen, Daniel Serrano, Farnaz Ghobadi, Marian Mayhue, Kasper Hoebe, Subburaj Ilangumaran, Sheela Ramanathan

published 29 Mar 2016

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The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis

Juliane Braun, Arabella Meixner, Andreas Brachner, Roland Foisner

published 24 Mar 2016

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Earth Mover’s Distance (EMD): A True Metric for Comparing Biomarker Expression Levels in Cell Populations

Darya Y. Orlova, Noah Zimmerman, Stephen Meehan, Connor Meehan, Jeffrey Waters, Eliver E. B. Ghosn, Alexander Filatenkov, Gleb A. Kolyagin, Yael Gernez, Shanel Tsuda, Wayne Moore, Richard B. Moss, Leonore A. Herzenberg, Guenther Walther

published 23 Mar 2016

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Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3L423P Mutant Mice

Sudhir Kumar, Birgit Rathkolb, Elisabeth Kemter, Sibylle Sabrautzki, Dian Michel, Thure Adler, Lore Becker, Johannes Beckers, Dirk H. Busch, Lillian Garrett, Wolfgang Hans, Sabine M. Hölter, Marion Horsch, Martin Klingenspor, Thomas Klopstock, Ildikó Rácz, Jan Rozman, Ingrid Liliana Vargas Panesso, Alexandra Vernaleken, Andreas Zimmer, Helmut Fuchs, Valérie Gailus-Durner, Martin Hrabě de Angelis, Eckhard Wolf, Bernhard Aigner

published 22 Mar 2016

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Autophagy Limits Endotoxemic Acute Kidney Injury and Alters Renal Tubular Epithelial Cell Cytokine Expression

Jeremy S. Leventhal, Jie Ni, Morgan Osmond, Kyung Lee, G. Luca Gusella, Fadi Salem, Michael J. Ross

published 18 Mar 2016

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