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Genetically modified animals

Development and Preclinical Application of an Immunocompetent Transplant Model of Basal Breast Cancer with Lung, Liver and Brain Metastases

Olga Aprelikova, Christine C. Tomlinson, Mark Hoenerhoff, Julie A. Hixon, Scott K. Durum, Ting-hu Qiu, Siping He, Sandra Burkett, Zi-Yao Liu, Steven M. Swanson, Jeffrey E. Green

published 12 May 2016

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Lipopolysaccharide Is Cleared from the Circulation by Hepatocytes via the Low Density Lipoprotein Receptor

Elena Topchiy, Mihai Cirstea, HyeJin Julia Kong, John H. Boyd, Yingjin Wang, James A. Russell, Keith R. Walley

published 12 May 2016

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Endotoxin Disrupts Circadian Rhythms in Macrophages via Reactive Oxygen Species

Yusi Wang, Paramita Pati, Yiming Xu, Feng Chen, David W. Stepp, Yuqing Huo, R. Daniel Rudic, David J. R. Fulton

published 11 May 2016

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Histopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatment

Palittiya Sintusek, Francesco Catapano, Napat Angkathunkayul, Elena Marrosu, Simon H. Parson, Jennifer E. Morgan, Francesco Muntoni, Haiyan Zhou

published 10 May 2016

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Epidermal Growth Factor Receptor in Prostate Cancer Derived Exosomes

Geetanjali Kharmate, Elham Hosseini-Beheshti, Josselin Caradec, Mei Yieng Chin, Emma S. Tomlinson Guns

published 06 May 2016

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Stat3 Is Important for Follicular Regulatory T Cell Differentiation

Hao Wu, Markus M. Xie, Hong Liu, Alexander L. Dent

published 05 May 2016

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Human Bacterial Artificial Chromosome (BAC) Transgenesis Fully Rescues Noradrenergic Function in Dopamine β-Hydroxylase Knockout Mice

Joseph F. Cubells, Jason P. Schroeder, Elizabeth S. Barrie, Daniel F. Manvich, Wolfgang Sadee, Tiina Berg, Kristina Mercer, Taylor A. Stowe, L. Cameron Liles, Katherine E. Squires, Andrew Mezher, Patrick Curtin, Dannie L. Perdomo, Patricia Szot, David Weinshenker

published 05 May 2016

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Transposon-Based Reporter Marking Provides Functional Evidence for Intercellular Bridges in the Male Germline of Rabbits

Orsolya I. Hoffmann, Andrea Kerekes, Nandor Lipták, Laszlo Hiripi, Szilard Bodo, Gabor Szaloki, Sabine Klein, Zoltan Ivics, Wilfried A. Kues, Zsuzsanna Bosze

published 05 May 2016

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Shortened Lifespan and Lethal Hemorrhage in a Hemophilia A Mouse Model

Janice M. Staber, Molly J. Pollpeter

published 04 May 2016

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Advanced Glycation Endproducts and Bone Material Properties in Type 1 Diabetic Mice

Mishaela R. Rubin, Eleftherios P. Paschalis, Atharva Poundarik, Gyna E. Sroga, Donald J. McMahon, Sonja Gamsjaeger, Klaus Klaushofer, Deepak Vashishth

published 03 May 2016

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Loss of Pcgf5 Affects Global H2A Monoubiquitination but Not the Function of Hematopoietic Stem and Progenitor Cells

Sha Si, Yaeko Nakajima-Takagi, Kazumasa Aoyama, Motohiko Oshima, Atsunori Saraya, Hiroki Sugishita, Manabu Nakayama, Tomoyuki Ishikura, Haruhiko Koseki, Atsushi Iwama

published 02 May 2016

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A Novel Model of Intravital Platelet Imaging Using CD41-ZsGreen1 Transgenic Rats

Makoto Mizuno, Atsuyuki Tomizawa, Kousaku Ohno, Joseph A. Jakubowski, Atsuhiro Sugidachi

published 29 Apr 2016

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Combined Id1 and Id3 Deletion Leads to Severe Erythropoietic Disturbances

Qingshi Zhao, Corey Chang, J. Patrick Gonzalez, Kamal Alzahrani, Jessica L Button, Diego Fraidenraich

published 29 Apr 2016

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