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Genetically modified animals

A New Mouse Model That Spontaneously Develops Chronic Liver Inflammation and Fibrosis

Nina Fransén-Pettersson, Nadia Duarte, Julia Nilsson, Marie Lundholm, Sofia Mayans, Åsa Larefalk, Tine D. Hannibal, Lisbeth Hansen, Anja Schmidt-Christensen, Fredrik Ivars, Susanna Cardell, Richard Palmqvist, Björn Rozell, Dan Holmberg

published 21 Jul 2016

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Inhibition of the Unfolded Protein Response Mechanism Prevents Cardiac Fibrosis

Jody Groenendyk, Dukgyu Lee, Joanna Jung, Jason R. B. Dyck, Gary D. Lopaschuk, Luis B. Agellon, Marek Michalak

published 21 Jul 2016

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Loss of Fertility in the Absence of Progesterone Receptor Expression in Kisspeptin Neurons of Female Mice

Arnon Gal, Po-Ching Lin, Joseph A. Cacioppo, Patrick R. Hannon, Megan M. Mahoney, Andrew Wolfe, Rodrigo Fernandez-Valdivia, John P. Lydon, Carol F. Elias, CheMyong Ko

published 21 Jul 2016

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Critical Role of Kupffer Cell CD89 Expression in Experimental IgA Nephropathy

Lijun Xu, Bingyu Li, Mengwen Huang, Kun Xie, Dong Li, You Li, Hua Gu, Jianmin Fang

published 20 Jul 2016

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XRP44X, an Inhibitor of Ras/Erk Activation of the Transcription Factor Elk3, Inhibits Tumour Growth and Metastasis in Mice

Kostyantyn Semenchenko, Christine Wasylyk, Henry Cheung, Yves Tourrette, Peter Maas, Jack A Schalken, Gabri van der Pluijm, Bohdan Wasylyk

published 18 Jul 2016

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Gremlin-1 Overexpression in Mouse Lung Reduces Silica-Induced Lymphocyte Recruitment – A Link to Idiopathic Pulmonary Fibrosis through Negative Correlation with CXCL10 Chemokine

Katri Koli, Eva Sutinen, Mikko Rönty, Pia Rantakari, Vittorio Fortino, Ville Pulkkinen, Dario Greco, Petra Sipilä, Marjukka Myllärniemi

published 18 Jul 2016

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The Influence of Differentially Expressed Tissue-Type Plasminogen Activator in Experimental Autoimmune Encephalomyelitis: Implications for Multiple Sclerosis

Lisa CM Dahl, Zeyad Nasa, JieYu Chung, Be’eri Niego, Volga Tarlac, Heidi Ho, Adam Galle, Steven Petratos, Jae Young Lee, Frank Alderuccio, Robert L. Medcalf

published 18 Jul 2016

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Subacute Changes in Cleavage Processing of Amyloid Precursor Protein and Tau following Penetrating Traumatic Brain Injury

Casandra M. Cartagena, Andrea Mountney, Hye Hwang, Adam Swiercz, Zoe Rammelkamp, Angela M. Boutte, Deborah A. Shear, Frank C. Tortella, Kara E. Schmid

published 18 Jul 2016

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Long-Term Treatment with Liraglutide, a Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist, Has No Effect on β-Amyloid Plaque Load in Two Transgenic APP/PS1 Mouse Models of Alzheimer’s Disease

Henrik H. Hansen, Katrine Fabricius, Pernille Barkholt, Pernille Kongsbak-Wismann, Chantal Schlumberger, Jacob Jelsing, Dick Terwel, Annelies Termont, Charles Pyke, Lotte Bjerre Knudsen, Niels Vrang

published 15 Jul 2016

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Preparation and Evaluation of Oxaliplatin Thermosensitive Liposomes with Rapid Release and High Stability

Chunying Zeng, Fanglin Yu, Yang Yang, Xiaohui Cheng, Yan Liu, Hui Zhang, Shiqing Zhao, Zhenbo Yang, Mingyuan Li, Zhiping Li, Xingguo Mei

published 14 Jul 2016

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Visualization of the Epiblast and Visceral Endodermal Cells Using Fgf5-P2A-Venus BAC Transgenic Mice and Epiblast Stem Cells

Le Tran Phuc Khoa, Takuya Azami, Tomoyuki Tsukiyama, Jun Matsushita, Setsuko Tsukiyama-Fujii, Satoru Takahashi, Masatsugu Ema

published 13 Jul 2016

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Beta-Catenin Haplo Insufficient Male Mice Do Not Lose Bone in Response to Hindlimb Unloading

Delphine B. Maurel, Peipei Duan, Joshua Farr, An-Lin Cheng, Mark L. Johnson, Lynda F. Bonewald

published 13 Jul 2016

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Differential Insulin Secretion of High-Fat Diet-Fed C57BL/6NN and C57BL/6NJ Mice: Implications of Mixed Genetic Background in Metabolic Studies

Camille Attané, Marie-Line Peyot, Roxane Lussier, Dongwei Zhang, Erik Joly, S. R. Murthy Madiraju, Marc Prentki

published 12 Jul 2016

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