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Genetically modified animals

Dearth and Delayed Maturation of Testicular Germ Cells in Fanconi Anemia E Mutant Male Mice

Chun Fu, Khurshida Begum, Philip W. Jordan, Yan He, Paul A. Overbeek

published 03 Aug 2016

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Activation of β-Catenin Signaling in CD133-Positive Dermal Papilla Cells Drives Postnatal Hair Growth

Linli Zhou, Mingang Xu, Yongguang Yang, Kun Yang, Randall R. Wickett, Thomas Andl, Sarah E. Millar, Yuhang Zhang

published 29 Jul 2016

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Enhancement of Oral Tolerance Induction in DO11.10 Mice by Lactobacillus gasseri OLL2809 via Increase of Effector Regulatory T Cells

Ayako Aoki-Yoshida, Kiyoshi Yamada, Satoshi Hachimura, Toshihiro Sashihara, Shuji Ikegami, Makoto Shimizu, Mamoru Totsuka

published 29 Jul 2016

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Endothelial-Specific EphA4 Negatively Regulates Native Pial Collateral Formation and Re-Perfusion following Hindlimb Ischemia

Benjamin Okyere, Kaavya Giridhar, Amanda Hazy, Miao Chen, David Keimig, Robert C. Bielitz, Hehuang Xie, Jia-Qiang He, William R. Huckle, Michelle H. Theus

published 28 Jul 2016

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Collecting Duct Renin Does Not Mediate DOCA-Salt Hypertension or Renal Injury

Kai Song, Deborah Stuart, Nikita Abraham, Fei Wang, Shuping Wang, Tianxin Yang, Curt D. Sigmund, Donald E. Kohan, Nirupama Ramkumar

published 28 Jul 2016

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Transgenic Rescue of the LARGE_myd Mouse: A LARGE Therapeutic Window?

J. C. W. Hildyard, E. Lacey, H. Booler, M. Hopkinson, D. J. Wells, S. C. Brown

published 28 Jul 2016

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Loss of Renal Tubular PGC-1α Exacerbates Diet-Induced Renal Steatosis and Age-Related Urinary Sodium Excretion in Mice

Kristoffer Svensson, Svenia Schnyder, Bettina Cardel, Christoph Handschin

published 27 Jul 2016

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Tau Protein Mediates APP Intracellular Domain (AICD)-Induced Alzheimer’s-Like Pathological Features in Mice

Kaushik Ghosal, Qingyuan Fan, Hana N. Dawson, Sanjay W. Pimplikar

published 26 Jul 2016

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Phenotypes Associated with Knockouts of Eight Dense Granule Gene Loci (GRA2-9) in Virulent Toxoplasma gondii

Leah M. Rommereim, Valeria Bellini, Barbara A. Fox, Graciane Pètre, Camille Rak, Bastien Touquet, Delphine Aldebert, Jean-François Dubremetz, Marie-France Cesbron-Delauw, Corinne Mercier, David J. Bzik

published 26 Jul 2016

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Tubular Overexpression of Angiopoietin-1 Attenuates Renal Fibrosis

Sudhir Singh, Scott R. Manson, Heedoo Lee, Yeawon Kim, Tuoen Liu, Qiusha Guo, Julio J. Geminiani, Paul F. Austin, Ying Maggie Chen

published 25 Jul 2016

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Retinal Neuroprotective Effects of Flibanserin, an FDA-Approved Dual Serotonin Receptor Agonist-Antagonist

Aaron S. Coyner, Renee C. Ryals, Cristy A. Ku, Cody M. Fischer, Rachel C. Patel, Shreya Datta, Paul Yang, Yuquan Wen, René Hen, Mark E. Pennesi

published 22 Jul 2016

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miR-9 Acts as an OncomiR in Prostate Cancer through Multiple Pathways That Drive Tumour Progression and Metastasis

S. J. Seashols-Williams, W. Budd, G. C. Clark, Q. Wu, R. Daniel, E. Dragoescu, Z. E. Zehner

published 22 Jul 2016

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Ablation of Prion Protein in Wild Type Human Amyloid Precursor Protein (APP) Transgenic Mice Does Not Alter The Proteolysis of APP, Levels of Amyloid-β or Pathologic Phenotype

Isobel J. Whitehouse, Deborah Brown, Herbert Baybutt, Abigail B. Diack, Katherine A. B. Kellett, Pedro Piccardo, Jean C. Manson, Nigel M. Hooper

published 22 Jul 2016

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