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Genetically modified animals

MUC18 Regulates Lung Rhinovirus Infection and Inflammation

Reena Berman, Di Jiang, Qun Wu, Connor R. Stevenson, Niccolette R. Schaefer, Hong Wei Chu

published 04 Oct 2016

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Transgenic Mice Expressing MCP-1 by the Urothelium Demonstrate Bladder Hypersensitivity, Pelvic Pain and Voiding Dysfunction: A Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research Network Animal Model Study

Suming Xu, Xu Wang, Yaoqin Wang, Susan Lutgendorf, Catherine Bradley, Andrew Schrepf, Karl Kreder, Michael O'Donnell, Yi Luo

published 29 Sep 2016

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Generation of VDR Knock-Out Mice via Zygote Injection of CRISPR/Cas9 System

Tao Zhang, Yajun Yin, Huan Liu, Weili Du, Chonghua Ren, Ling Wang, Hongzhao Lu, Zhiying Zhang

published 29 Sep 2016

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Motor Experience Reprograms Development of a Genetically-Altered Bilateral Corticospinal Motor Circuit

Najet Serradj, John H. Martin

published 27 Sep 2016

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NSG Mice Provide a Better Spontaneous Model of Breast Cancer Metastasis than Athymic (Nude) Mice

Madhavi Puchalapalli, Xianke Zeng, Liang Mu, Aubree Anderson, Laura Hix Glickman, Ming Zhang, Megan R. Sayyad, Sierra Mosticone Wangensteen, Charles V. Clevenger, Jennifer E. Koblinski

published 23 Sep 2016

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Selenotranscriptomic Analyses Identify Signature Selenoproteins in Brain Regions in a Mouse Model of Parkinson’s Disease

Xiong Zhang, Yang-Lie Ye, Hui Zhu, Sheng-Nan Sun, Jing Zheng, Hui-Hui Fan, Hong-Mei Wu, Song-Fang Chen, Wen-Hsing Cheng, Jian-Hong Zhu

published 22 Sep 2016

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Disease Phenotypes in a Mouse Model of RNA Toxicity Are Independent of Protein Kinase Cα and Protein Kinase Cβ

Yun K. Kim, Ramesh S. Yadava, Mahua Mandal, Karunasai Mahadevan, Qing Yu, Michael Leitges, Mani S. Mahadevan

published 22 Sep 2016

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Normal Development and Function of T Cells in Proline Rich 7 (Prr7) Deficient Mice

Matous Hrdinka, Kritika Sudan, Sissy Just, Ales Drobek, Ondrej Stepanek, Dirk Schlüter, Dirk Reinhold, Bryen A. Jordan, Patricia Gintschel, Burkhart Schraven, Michael R. Kreutz

published 22 Sep 2016

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Vimentin, a Novel NF-κB Regulator, Is Required for Meningitic Escherichia coli K1-Induced Pathogen Invasion and PMN Transmigration across the Blood-Brain Barrier

Sheng-He Huang, Feng Chi, Liang Peng, Tao Bo, Bao Zhang, Li-Qun Liu, Xuedong Wu, Nirit Mor-Vaknin, David M. Markovitz, Hong Cao, Yan-Hong Zhou

published 22 Sep 2016

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KLHDC10 Deficiency Protects Mice against TNFα-Induced Systemic Inflammation

Namiko Yamaguchi, Shiori Sekine, Isao Naguro, Yusuke Sekine, Hidenori Ichijo

published 15 Sep 2016

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Disruption of Rest Leads to the Early Onset of Cataracts with the Aberrant Terminal Differentiation of Lens Fiber Cells

Hitomi Aoki, Hajime Ogino, Hiroyuki Tomita, Akira Hara, Takahiro Kunisada

published 15 Sep 2016

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BOULE, a Deleted in Azoospermia Homolog, Is Recruited to Stress Granules in the Mouse Male Germ Cells

Byunghyuk Kim, Kunsoo Rhee

published 15 Sep 2016

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Evaluating Tissue-Specific Recombination in a Pdgfrα-CreERT2 Transgenic Mouse Line

Megan O’Rourke, Carlie L. Cullen, Loic Auderset, Kimberley A. Pitman, Daniela Achatz, Robert Gasperini, Kaylene M. Young

published 14 Sep 2016

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