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Genetically modified animals

Mammalian-Specific Central Myelin Protein Opalin Is Redundant for Normal Myelination: Structural and Behavioral Assessments

Fumio Yoshikawa, Yumi Sato, Koujiro Tohyama, Takumi Akagi, Tamio Furuse, Tetsushi Sadakata, Mika Tanaka, Yo Shinoda, Tsutomu Hashikawa, Shigeyoshi Itohara, Yoshitake Sano, M. Said Ghandour, Shigeharu Wakana, Teiichi Furuichi

published 17 Nov 2016

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Impact of the B Cell Growth Factor APRIL on the Qualitative and Immunological Characteristics of Atherosclerotic Plaques

Sophie J. Bernelot Moens, Sander I. van Leuven, Kang H. Zheng, Stefan R. Havik, Miranda V. Versloot, Leonie M. van Duivenvoorde, Michael Hahne, Erik S. G. Stroes, Dominique L. Baeten, Anouk A. J. Hamers

published 07 Nov 2016

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The Influenza Virus Protein PB1-F2 Increases Viral Pathogenesis through Neutrophil Recruitment and NK Cells Inhibition

Aurore Vidy, Pauline Maisonnasse, Bruno Da Costa, Bernard Delmas, Christophe Chevalier, Ronan Le Goffic

published 31 Oct 2016

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Failure to Genotype: A Cautionary Note on an Elusive loxP Sequence

Johan Kreuger, Paul O’Callaghan

published 21 Oct 2016

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Characterization of Pharmacologic and Pharmacokinetic Properties of CCX168, a Potent and Selective Orally Administered Complement 5a Receptor Inhibitor, Based on Preclinical Evaluation and Randomized Phase 1 Clinical Study

Pirow Bekker, Daniel Dairaghi, Lisa Seitz, Manmohan Leleti, Yu Wang, Linda Ertl, Trageen Baumgart, Sarah Shugarts, Lisa Lohr, Ton Dang, Shichang Miao, Yibin Zeng, Pingchen Fan, Penglie Zhang, Daniel Johnson, Jay Powers, Juan Jaen, Israel Charo, Thomas J. Schall

published 21 Oct 2016

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Nemo-Like Kinase (NLK) Is a Pathological Signaling Effector in the Mouse Heart

Ruijie Liu, Hadi Khalil, Suh-Chin J. Lin, Michelle A. Sargent, Allen J. York, Jeffery D. Molkentin

published 20 Oct 2016

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Increased Growth of a Newly Established Mouse Epithelial Cell Line Transformed with HPV-16 E7 in Diabetic Mice

Lan He, Priscilla T. Y. Law, Siaw Shi Boon, Chuqing Zhang, Wendy C. S. Ho, Lawrence Banks, C. K. Wong, Juliana C. N. Chan, Paul K. S. Chan

published 17 Oct 2016

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A Novel Class of Small Molecule Agonists with Preference for Human over Mouse TLR4 Activation

Jason D. Marshall, Darren S. Heeke, Eileen Rao, Sean K. Maynard, David Hornigold, Christopher McCrae, Neil Fraser, Andrey Tovchigrechko, Li Yu, Nicola Williams, Sarah King, Martin E. Cooper, Adeline M. Hajjar, Jennifer C. Woo

published 13 Oct 2016

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Refinement of the HIVAN1 Susceptibility Locus on Chr. 3A1-A3 via Generation of Sub-Congenic Strains

Natalia Papeta, Ami Patel, Vivette D. D’Agati, Ali G. Gharavi

published 13 Oct 2016

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Heparanase Overexpression Reduces Hepcidin Expression, Affects Iron Homeostasis and Alters the Response to Inflammation

Michela Asperti, Tanja Stuemler, Maura Poli, Magdalena Gryzik, Lena Lifshitz, Esther G. Meyron-Holtz, Israel Vlodavsky, Paolo Arosio

published 06 Oct 2016

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Enlargement of the Axial Length and Altered Ultrastructural Features of the Sclera in a Mutant Lumican Transgenic Mouse Model

Yanzheng Song, Fengju Zhang, Yanyan Zhao, Mingshen Sun, Jun Tao, Yanchuang Liang, Ling Ma, Yanqiu Yu, Jianhua Wang, Junfeng Hao

published 06 Oct 2016

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Signaling of Prostaglandin E Receptors, EP3 and EP4 Facilitates Wound Healing and Lymphangiogenesis with Enhanced Recruitment of M2 Macrophages in Mice

Kanako Hosono, Risa Isonaka, Tadashi Kawakami, Shuh Narumiya, Masataka Majima

published 06 Oct 2016

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Augmented Growth Hormone Secretion and Stat3 Phosphorylation in an Aryl Hydrocarbon Receptor Interacting Protein (AIP)-Disrupted Somatotroph Cell Line

Takashi Fukuda, Tomoko Tanaka, Yuriko Hamaguchi, Takako Kawanami, Takashi Nomiyama, Toshihiko Yanase

published 05 Oct 2016

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