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Genetically modified animals

The Variability of the Harlequin Mouse Phenotype Resembles that of Human Mitochondrial-Complex I-Deficiency Syndromes

Paule Bénit, Sergio Goncalves, Emmanuel Philippe Dassa, Jean-Jacques Brière, Pierre Rustin

published 15 Sep 2008

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Cthrc1 Is a Positive Regulator of Osteoblastic Bone Formation

Hiroaki Kimura, Kin Ming Kwan, Zhaoping Zhang, Jian Min Deng, Bryant G. Darnay, Richard R. Behringer, Takashi Nakamura, Benoit de Crombrugghe, Haruhiko Akiyama

published 09 Sep 2008

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Receptor-Associated Protein (RAP) Plays a Central Role in Modulating Aβ Deposition in APP/PS1 Transgenic Mice

Guilian Xu, Celeste Karch, Ning Li, Nianwei Lin, David Fromholt, Victoria Gonzales, David R. Borchelt

published 08 Sep 2008

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IL-21 Limits Peripheral Lymphocyte Numbers through T Cell Homeostatic Mechanisms

Shrimati Datta, Nora E. Sarvetnick

published 05 Sep 2008

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Cre-Dependent Expression of Multiple Transgenes in Isolated Neurons of the Adult Forebrain

Sridhara Chakravarthy, Tara Keck, Martijn Roelandse, Robin Hartman, Andreas Jeromin, Sean Perry, Sonja B. Hofer, Thomas Mrsic-Flogel, Christiaan N. Levelt

published 26 Aug 2008

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GABA_A Receptor-Mediated Acceleration of Aging-Associated Memory Decline in APP/PS1 Mice and Its Pharmacological Treatment by Picrotoxin

Yuji Yoshiike, Tetsuya Kimura, Shunji Yamashita, Hiroyuki Furudate, Tatsuya Mizoroki, Miyuki Murayama, Akihiko Takashima

published 21 Aug 2008

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Control of Bone Mass and Remodeling by PTH Receptor Signaling in Osteocytes

Charles A. O'Brien, Lilian I. Plotkin, Carlo Galli, Joseph J. Goellner, Arancha R. Gortazar, Matthew R. Allen, Alexander G. Robling, Mary Bouxsein, Ernestina Schipani, Charles H. Turner, Robert L. Jilka, Robert S. Weinstein, Stavros C. Manolagas, Teresita Bellido

published 13 Aug 2008

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No Major Change in vCJD Agent Strain after Secondary Transmission via Blood Transfusion

Matthew T. Bishop, Diane L. Ritchie, Robert G. Will, James W. Ironside, Mark W. Head, Val Thomson, Moira Bruce, Jean C. Manson

published 06 Aug 2008

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Impairment of Adolescent Hippocampal Plasticity in a Mouse Model for Alzheimer's Disease Precedes Disease Phenotype

Daniela Hartl, Michael Rohe, Lei Mao, Matthias Staufenbiel, Claus Zabel, Joachim Klose

published 23 Jul 2008

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Tankyrase 1 and Tankyrase 2 Are Essential but Redundant for Mouse Embryonic Development

Y. Jeffrey Chiang, Susan J. Hsiao, Dena Yver, Samuel W. Cushman, Lino Tessarollo, Susan Smith, Richard J. Hodes

published 09 Jul 2008

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RelB-Dependent Stromal Cells Promote T-Cell Leukemogenesis

Nuno R. dos Santos, Maryvonne Williame, Stéphanie Gachet, Françoise Cormier, Anne Janin, Debra Weih, Falk Weih, Jacques Ghysdael

published 02 Jul 2008

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Modified Ca_v1.4 Expression in the Cacna1fnob2 Mouse Due to Alternative Splicing of an ETn Inserted in Exon 2

Clinton J. Doering, Renata Rehak, Stephan Bonfield, Jean B. Peloquin, William K. Stell, Silvina C. Mema, Yves Sauvé, John E. McRory

published 02 Jul 2008

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Marking Embryonic Stem Cells with a 2A Self-Cleaving Peptide: A NKX2-5 Emerald GFP BAC Reporter

Edward C. Hsiao, Yuko Yoshinaga, Trieu D. Nguyen, Stacy L. Musone, Judy E. Kim, Paul Swinton, Isidro Espineda, Carlota Manalac, Pieter J. deJong, Bruce R. Conklin

published 02 Jul 2008

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