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Genetically modified animals

Deficiency of FLCN in Mouse Kidney Led to Development of Polycystic Kidneys and Renal Neoplasia

Jindong Chen, Kunihiko Futami, David Petillo, Jun Peng, Pengfei Wang, Jared Knol, Yan Li, Sok-Kean Khoo, Dan Huang, Chao-Nan Qian, Ping Zhao, Karl Dykyma, Racheal Zhang, Brian Cao, Ximing J. Yang, Kyle Furge, Bart O. Williams, Bin Tean Teh

published 30 Oct 2008

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Adherent Monomer-Misfolded SOD1

Yasuhiro Watanabe, Eri Morita, Yasuyo Fukada, Koji Doi, Kenichi Yasui, Michio Kitayama, Toshiya Nakano, Kenji Nakashima

published 23 Oct 2008

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Cattle Mammary Bioreactor Generated by a Novel Procedure of Transgenic Cloning for Large-Scale Production of Functional Human Lactoferrin

Penghua Yang, Jianwu Wang, Guochun Gong, Xiuzhu Sun, Ran Zhang, Zhuo Du, Ying Liu, Rong Li, Fangrong Ding, Bo Tang, Yunping Dai, Ning Li

published 20 Oct 2008

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Genetic Disruption of Both Tryptophan Hydroxylase Genes Dramatically Reduces Serotonin and Affects Behavior in Models Sensitive to Antidepressants

Katerina V. Savelieva, Shulei Zhao, Vladimir M. Pogorelov, Indrani Rajan, Qi Yang, Emily Cullinan, Thomas H. Lanthorn

published 15 Oct 2008

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Somatic ‘Soluble’ Adenylyl Cyclase Isoforms Are Unaffected in Sacy^tm1Lex/Sacy^tm1Lex ‘Knockout’ Mice

Jeanne Farrell, Lavoisier Ramos, Martin Tresguerres, Margarita Kamenetsky, Lonny R. Levin, Jochen Buck

published 22 Sep 2008

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Magic-Factor 1, a Partial Agonist of Met, Induces Muscle Hypertrophy by Protecting Myogenic Progenitors from Apoptosis

Marco Cassano, Stefano Biressi, Amanda Finan, Laura Benedetti, Claudia Omes, Renata Boratto, Frank Martin, Marcello Allegretti, Vania Broccoli, Gabriella Cusella De Angelis, Paolo M. Comoglio, Cristina Basilico, Yvan Torrente, Paolo Michieli, Giulio Cossu, Maurilio Sampaolesi

published 16 Sep 2008

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The Variability of the Harlequin Mouse Phenotype Resembles that of Human Mitochondrial-Complex I-Deficiency Syndromes

Paule Bénit, Sergio Goncalves, Emmanuel Philippe Dassa, Jean-Jacques Brière, Pierre Rustin

published 15 Sep 2008

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Cthrc1 Is a Positive Regulator of Osteoblastic Bone Formation

Hiroaki Kimura, Kin Ming Kwan, Zhaoping Zhang, Jian Min Deng, Bryant G. Darnay, Richard R. Behringer, Takashi Nakamura, Benoit de Crombrugghe, Haruhiko Akiyama

published 09 Sep 2008

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Receptor-Associated Protein (RAP) Plays a Central Role in Modulating Aβ Deposition in APP/PS1 Transgenic Mice

Guilian Xu, Celeste Karch, Ning Li, Nianwei Lin, David Fromholt, Victoria Gonzales, David R. Borchelt

published 08 Sep 2008

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IL-21 Limits Peripheral Lymphocyte Numbers through T Cell Homeostatic Mechanisms

Shrimati Datta, Nora E. Sarvetnick

published 05 Sep 2008

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Cre-Dependent Expression of Multiple Transgenes in Isolated Neurons of the Adult Forebrain

Sridhara Chakravarthy, Tara Keck, Martijn Roelandse, Robin Hartman, Andreas Jeromin, Sean Perry, Sonja B. Hofer, Thomas Mrsic-Flogel, Christiaan N. Levelt

published 26 Aug 2008

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GABA_A Receptor-Mediated Acceleration of Aging-Associated Memory Decline in APP/PS1 Mice and Its Pharmacological Treatment by Picrotoxin

Yuji Yoshiike, Tetsuya Kimura, Shunji Yamashita, Hiroyuki Furudate, Tatsuya Mizoroki, Miyuki Murayama, Akihiko Takashima

published 21 Aug 2008

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Control of Bone Mass and Remodeling by PTH Receptor Signaling in Osteocytes

Charles A. O'Brien, Lilian I. Plotkin, Carlo Galli, Joseph J. Goellner, Arancha R. Gortazar, Matthew R. Allen, Alexander G. Robling, Mary Bouxsein, Ernestina Schipani, Charles H. Turner, Robert L. Jilka, Robert S. Weinstein, Stavros C. Manolagas, Teresita Bellido

published 13 Aug 2008

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