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Genetically modified animals

The cyclophilin inhibitor CRV431 inhibits liver HBV DNA and HBsAg in transgenic mice

Philippe Gallay, Daren Ure, Michael Bobardt, Udayan Chatterji, James Ou, Daniel Trepanier, Robert Foster

published 10 Jun 2019

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Constitutive inhibitory G protein activity upon adenylyl cyclase-dependent cardiac contractility is limited to adenylyl cyclase type 6

Caroline Bull Melsom, Marie-Victoire Cosson, Øivind Ørstavik, Ngai Chin Lai, H. Kirk Hammond, Jan-Bjørn Osnes, Tor Skomedal, Viacheslav Nikolaev, Finn Olav Levy, Kurt Allen Krobert

published 07 Jun 2019

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Trafficking of immune cells across the blood-brain barrier is modulated by neurofibrillary pathology in tauopathies

Petra Majerova, Alena Michalicova, Martin Cente, Jozef Hanes, Jozef Vegh, Agnes Kittel, Nina Kosikova, Viera Cigankova, Sandra Mihaljevic, Santosh Jadhav, Andrej Kovac

published 23 May 2019

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Sevoflurane increases locomotion activity in mice

Hoai T. Ton, Lei Yang, Zhongcong Xie

published 21 May 2019

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Carvedilol inhibits EGF-mediated JB6 P+ colony formation through a mechanism independent of adrenoceptors

Kristan H. Cleveland, Sherry Liang, Andy Chang, Kevin M. Huang, Si Chen, Lei Guo, Ying Huang, Bradley T. Andresen

published 20 May 2019

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Dopamine-dependent, swimming-induced paralysis arises as a consequence of loss of function mutations in the RUNX transcription factor RNT-1

Sarah B. Robinson, Osama Refai, J. Andrew Hardaway, Sarah Sturgeon, Tessa Popay, Daniel P. Bermingham, Phyllis Freeman, Jane Wright, Randy D. Blakely

published 13 May 2019

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Reliability of blood lactate as a measure of exercise intensity in different strains of mice during forced treadmill running

Simon Lønbro, Jennifer M. Wiggins, Thomas Wittenborn, Pernille Byrialsen Elming, Lori Rice, Christine Pampo, Jennifer A. Lee, Dietmar W. Siemann, Michael R. Horsman

published 03 May 2019

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Natural variation in the roles of C. elegans autophagy components during microsporidia infection

Keir M. Balla, Vladimir Lažetić, Emily R. Troemel

published 23 Apr 2019

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Copper transporter 1 (CTR1) expression by mouse testicular germ cells, but not Sertoli cells, is essential for functional spermatogenesis

Rashin Ghaffari, Kristin R. Di Bona, Christopher L. Riley, John H. Richburg

published 19 Apr 2019

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Wide sensory filters underlie performance in memory-based discrimination and generalization

Chi Chen, Dilja Krueger-Burg, Livia de Hoz

published 18 Apr 2019

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APOL1 renal risk variants promote cholesterol accumulation in tissues and cultured macrophages from APOL1 transgenic mice

Jung-Hwa Ryu, Mengyuan Ge, Sandra Merscher, Avi Z. Rosenberg, Marco Desante, Hila Roshanravan, Koji Okamoto, Myung K. Shin, Maarten Hoek, Alessia Fornoni, Jeffrey B. Kopp

published 18 Apr 2019

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Targeted disruption of glycogen synthase kinase-3β in cardiomyocytes attenuates cardiac parasympathetic dysfunction in type 1 diabetic Akita mice

Yali Zhang, Charles M. Welzig, Marian Haburcak, Bo Wang, Mark Aronovitz, Robert M. Blanton, Ho-Jin Park, Thomas Force, Sami Noujaim, Jonas B. Galper

published 12 Apr 2019

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GTS-21 has cell-specific anti-inflammatory effects independent of α7 nicotinic acetylcholine receptors

Brijesh K. Garg, Ralph H. Loring

published 04 Apr 2019

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