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Genetically modified animals

A Novel TCR Transgenic Model Reveals That Negative Selection Involves an Immediate, Bim-Dependent Pathway and a Delayed, Bim-Independent Pathway

Damian Kovalovsky, Mark Pezzano, Benjamin D. Ortiz, Derek B. Sant'Angelo

published 13 Jan 2010

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Overexpression of CD97 in Intestinal Epithelial Cells of Transgenic Mice Attenuates Colitis by Strengthening Adherens Junctions

Susann Becker, Elke Wandel, Manja Wobus, Rick Schneider, Salah Amasheh, Doreen Sittig, Christiane Kerner, Ronald Naumann, Joerg Hamann, Gabriela Aust

published 13 Jan 2010

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Conditional Knockout of NMDA Receptors in Dopamine Neurons Prevents Nicotine-Conditioned Place Preference

Lei Phillip Wang, Fei Li, Xiaoming Shen, Joe Z. Tsien

published 07 Jan 2010

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Intravenously Administered Alphavirus Vector VA7 Eradicates Orthotopic Human Glioma Xenografts in Nude Mice

Jari E. Heikkilä, Markus J. V. Vähä-Koskela, Janne J. Ruotsalainen, Miika W. Martikainen, Marianne M. Stanford, J. Andrea McCart, John C. Bell, Ari E. Hinkkanen

published 06 Jan 2010

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Orexin-1 Receptor Co-Localizes with Pancreatic Hormones in Islet Cells and Modulates the Outcome of Streptozotocin-Induced Diabetes Mellitus

Ernest Adeghate, Maria Fernandez-Cabezudo, Rashed Hameed, Hussain El-Hasasna, Mohamed El Wasila, Tariq Abbas, Basel al-Ramadi

published 06 Jan 2010

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Enhanced Selection of High Affinity DNA-Reactive B Cells Following Cyclophosphamide Treatment in Mice

Daisuke Kawabata, Jeganathan Venkatesh, Meera Ramanujam, Anne Davidson, Christine M. Grimaldi, Betty Diamond

published 06 Jan 2010

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Diverse Hematological Malignancies Including Hodgkin-Like Lymphomas Develop in Chimeric MHC Class II Transgenic Mice

Silke H. Raffegerst, Gabriele Hoelzlwimmer, Sandra Kunder, Josef Mysliwietz, Leticia Quintanilla-Martinez, Dolores J. Schendel

published 31 Dec 2009

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CRF1-R Activation of the Dynorphin/Kappa Opioid System in the Mouse Basolateral Amygdala Mediates Anxiety-Like Behavior

Michael R. Bruchas, Benjamin B. Land, Julia C. Lemos, Charles Chavkin

published 31 Dec 2009

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Critical Role of Arcuate Y4 Receptors and the Melanocortin System in Pancreatic Polypeptide-Induced Reduction in Food Intake in Mice

Shu Lin, Yan-Chuan Shi, Ernie Yulyaningsih, Aygul Aljanova, Lei Zhang, Laurence Macia, Amy D. Nguyen, En-Ju Deborah Lin, Matthew J. During, Herbert Herzog, Amanda Sainsbury

published 30 Dec 2009

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IL-2 Regulates SEB Induced Toxic Shock Syndrome in BALB/c Mice

Aslam Ali Khan, Shilpee Priya, Bhaskar Saha

published 29 Dec 2009

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Increased Light Exposure Alleviates One Form of Photoreceptor Degeneration Marked by Elevated Calcium in the Dark

Xiaoqing Liu, Basil S. Pawlyk, Michael Adamian, Elena V. Olshevskaya, Alexander M. Dizhoor, Clint L. Makino, Tiansen Li

published 24 Dec 2009

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P21^cip-Overexpression in the Mouse β Cells Leads to the Improved Recovery from Streptozotocin-Induced Diabetes

Jie Yang, Weiqi Zhang, Wei Jiang, Xiaoning Sun, Yuhua Han, Mingxiao Ding, Yan Shi, Hongkui Deng

published 17 Dec 2009

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N-Cadherin Negatively Regulates Osteoblast Proliferation and Survival by Antagonizing Wnt, ERK and PI3K/Akt Signalling

Eric Haÿ, Alexandra Nouraud, Pierre J. Marie

published 14 Dec 2009

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