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Genetically modified animals

The adoptive transfer of BCG-induced T lymphocytes contributes to hippocampal cell proliferation and tempers anxiety-like behavior in immune deficient mice

Dan Song, Fangfang Qi, ShuaiShuai Liu, Zhongsheng Tang, Jinhai Duan, Zhibin Yao

published 02 Apr 2020

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Podocyte-specific deletion of tubular sclerosis complex 2 promotes focal segmental glomerulosclerosis and progressive renal failure

Wakiko Iwata, Hiroyuki Unoki-Kubota, Hideki Kato, Akira Shimizu, Michihiro Matsumoto, Toshiyuki Imasawa, Arisa Igarashi, Kenji Matsumoto, Tetsuo Noda, Yasuo Terauchi, Masaomi Nangaku, Masato Kasuga, Yasushi Kaburagi

published 19 Mar 2020

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Quantification of fluorophore distribution and therapeutic response in matched in vivo and ex vivo pancreatic cancer model systems

Allison Solanki, Diana King, Guillaume Thibault, Lei Wang, Summer L. Gibbs

published 25 Feb 2020

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High-speed automatic characterization of rare events in flow cytometric data

Yuan Qi, Youhan Fang, David R. Sinclair, Shangqin Guo, Meritxell Alberich-Jorda, Jun Lu, Daniel G. Tenen, Michael G. Kharas, Saumyadipta Pyne

published 11 Feb 2020

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Jmjd1c is dispensable for healthy adult hematopoiesis and Jak2^V617F-driven myeloproliferative disease initiation in mice

Hans F. Staehle, Johannes Heinemann, Albert Gruender, Anne M. Omlor, Heike Luise Pahl, Jonas Samuel Jutzi

published 04 Feb 2020

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Viral FLIP blocks Caspase-8 driven apoptosis in the gut in vivo

Barbara Ruder, Claudia Günther, Michael Stürzl, Markus Friedrich Neurath, Ethel Cesarman, Gianna Ballon, Christoph Becker

published 30 Jan 2020

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GLIPR1 expression is reduced in multiple myeloma but is not a tumour suppressor in mice

Natasha Friend, Jacqueline E. Noll, Khatora S. Opperman, Kimberley C. Clark, Krzysztof M. Mrozik, Kate Vandyke, Duncan R. Hewett, Andrew C. W. Zannettino

published 29 Jan 2020

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Expression of human lambda expands the repertoire of OmniChickens

Kathryn H. Ching, Kimberley Berg, Jacqueline Morales, Darlene Pedersen, William D. Harriman, Yasmina N. Abdiche, Philip A. Leighton

published 29 Jan 2020

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Alterations of aqueous humor Aβ levels in Aβ-infused and transgenic mouse models of Alzheimer disease

Da Eun Kwak, Taeho Ko, Han Seok Koh, Yong Woo Ji, Jisu Shin, Kyeonghwan Kim, Hye Yun Kim, Hyung-Keun Lee, YoungSoo Kim

published 10 Jan 2020

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Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice

Wei-Wen Lim, Benjamin Ng, Anissa Widjaja, Chen Xie, Liping Su, Nicole Ko, Sze-Yun Lim, Xiu-Yi Kwek, Stella Lim, Stuart Alexander Cook, Sebastian Schafer

published 09 Jan 2020

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Validation of Plasmodium vivax centromere and promoter activities using Plasmodium yoelii

Kittisak Thawnashom, Miho Kaneko, Phonepadith Xangsayarath, Nattawat Chaiyawong, Kazuhide Yahata, Masahito Asada, John H. Adams, Osamu Kaneko

published 20 Dec 2019

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Nexrutine and exercise similarly prevent high grade prostate tumors in transgenic mouse model

Darpan I. Patel, Kira Abuchowski, Roble Bedolla, Paul Rivas, Nicolas Musi, Robert Reddick, A. Pratap Kumar

published 19 Dec 2019

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Replacing murine insulin 1 with human insulin protects NOD mice from diabetes

Colleen M. Elso, Nicholas A. Scott, Lina Mariana, Emma I. Masterman, Andrew P. R. Sutherland, Helen E. Thomas, Stuart I. Mannering

published 10 Dec 2019

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