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Genetically modified animals

Thrombopoietin is required for full phenotype expression in a JAK2^V617F transgenic mouse model of polycythemia vera

Jerry L. Spivak, Akil Merchant, Donna M. Williams, Ophelia Rogers, Wanke Zhao, Amy Duffield, Linda S. Resar, Alison R. Moliterno, Zhizhuang J. Zhao

published 01 Jun 2020

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Resistance of the murine cornea to bacterial colonization during experimental dry eye

Stephanie J. Wan, Sophia Ma, David J. Evans, Suzanne M. J. Fleiszig

published 29 May 2020

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Long term effects of soluble endoglin and mild hypercholesterolemia in mice hearts

Barbora Vitverova, Iveta Najmanova, Matej Vicen, Katarina Tripska, Ivone Cristina Igreja Sa, Radek Hyspler, Miguel Pericacho, Petr Nachtigal

published 29 May 2020

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Runx3 prevents spontaneous colitis by directing the differentiation of anti-inflammatory mononuclear phagocytes

Shay Hantisteanu, Yosef Dicken, Varda Negreanu, Dalia Goldenberg, Ori Brenner, Dena Leshkowitz, Joseph Lotem, Ditsa Levanon, Yoram Groner

published 26 May 2020

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Ablation of Iah1, a candidate gene for diet-induced fatty liver, does not affect liver lipid accumulation in mice

Tomomi Masuya, Miyako Suzuki, Junko Tsujimura, Shinsaku Kanamori, Yuki Miyasaka, Tamio Ohno, Atsushi Murai, Fumihiko Horio, Misato Kobayashi

published 14 May 2020

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Rev-erbα heterozygosity produces a dose-dependent phenotypic advantage in mice

Ryan D. Welch, Cyrielle Billon, Amina Kameric, Thomas P. Burris, Colin A. Flaveny

published 14 May 2020

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Stanniocalcin-1 (STC-1), a downstream effector molecule in latanoprost signaling, acts independent of the FP receptor for intraocular pressure reduction

Gavin W. Roddy, Tommy A. Rinkoski, Kjersten J. Monson, Uttio Roy Chowdhury, Michael P. Fautsch

published 04 May 2020

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Placental defects lead to embryonic lethality in mice lacking the Formin and PCP proteins Daam1 and Daam2

Masa-aki Nakaya, Kristibjorn Orri Gudmundsson, Yuko Komiya, Jonathan R. Keller, Raymond Habas, Terry P. Yamaguchi, Rieko Ajima

published 30 Apr 2020

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S-Nitrosylation of G protein-coupled receptor kinase 6 and Casein kinase 2 alpha modulates their kinase activity toward alpha-synuclein phosphorylation in an animal model of Parkinson’s disease

Weiwei Wu, Chun Chau Sung, Peichun Yu, Jiahua Li, Kenny K. K. Chung

published 28 Apr 2020

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Mouse dead end1 acts with Nanos2 and Nanos3 to regulate testicular teratoma incidence

Atsuki Imai, Yoshihiko Hagiwara, Yuki Niimi, Toshinobu Tokumoto, Yumiko Saga, Atsushi Suzuki

published 27 Apr 2020

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Deficiency of Crif1 in hair follicle stem cells retards hair growth cycle in adult mice

Jung-Min Shin, Jung-Woo Ko, Chong-Won Choi, Young Lee, Young-Joon Seo, Jeung-Hoon Lee, Chang-Deok Kim

published 24 Apr 2020

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Opposing effects of HNP1 (α-defensin-1) on plasma cholesterol and atherogenesis

Mohamed Higazi, Suhair Abdeen, Rami Abu-Fanne, Samuel N. Heyman, Aseel Masarwy, Khalil Bdeir, Emad Maraga, Douglas B. Cines, Abd Al-Roof Higazi

published 17 Apr 2020

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Genetic deletion of Autotaxin from CD11b⁺ cells decreases the severity of experimental autoimmune encephalomyelitis

Ioanna Ninou, Ioanna Sevastou, Christiana Magkrioti, Eleanna Kaffe, George Stamatakis, Spyros Thivaios, George Panayotou, Junken Aoki, George Kollias, Vassilis Aidinis

published 02 Apr 2020

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