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Genetically modified animals

Transient IL-33 upregulation in neonatal mouse lung promotes acute but not chronic type 2 immune responses induced by allergen later in life

Koji Iijima, Takao Kobayashi, Koji Matsumoto, Kenzo Ohara, Hirohito Kita, Li Y. Drake

published 28 May 2021

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DSPP dosage affects tooth development and dentin mineralization

Dandrich Lim, Ko-Chien Wu, Arthur Lee, Thomas L. Saunders, Helena H. Ritchie

published 26 May 2021

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Reduced CXCL1 production by endogenous IL-37 expressing dendritic cells does not affect T cell activation

M. Kouwenberg, W. P. C. Pulskens, L. Diepeveen, M. Bakker-van Bebber, C. A. Dinarello, M. G. Netea, L. B. Hilbrands, J. van der Vlag

published 24 May 2021

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Priming of myelin-specific T cells in the absence of dendritic cells results in accelerated development of Experimental Autoimmune Encephalomyelitis

Thaiphi Luu, Julie F. Cheung, Jennifer Baccon, Hanspeter Waldner

published 23 Apr 2021

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Comprehensive mutagenesis identifies the peptide repertoire of a p53 T-cell receptor mimic antibody that displays no toxicity in mice transgenic for human HLA-A*0201

Iva Trenevska, Amanda P. Anderson, Carol Bentley, Tasneem Hassanali, Sarah Wiblin, Shaun Maguire, Francesco Pezzella, Alison H. Banham, Demin Li

published 09 Apr 2021

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Generation and characterization of a Meflin-CreER^T2 transgenic line for lineage tracing in white adipose tissue

Takahide Kuwano, Hironori Izumi, Muhammad Rahil Aslam, Yoshiko Igarashi, Muhammad Bilal, Ayumi Nishimura, Yoshiyuki Watanabe, Allah Nawaz, Tomonobu Kado, Koichi Ikuta, Seiji Yamamoto, Masakiyo Sasahara, Shiho Fujisaka, Kunimasa Yagi, Hisashi Mori, Kazuyuki Tobe

published 24 Mar 2021

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Tet1 is not required for myeloid leukemogenesis by MLL-ENL in novel mouse models

Ryoichi Ono, Masahiro Masuya, Naokazu Inoue, Makoto Shinmei, Satomi Ishii, Yuri Maegawa, Bishnu Devi Maharjan, Naoyuki Katayama, Tetsuya Nosaka

published 11 Mar 2021

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Effect of conditional deletion of cytoplasmic dynein heavy chain DYNC1H1 on postnatal photoreceptors

Tiffanie M. Dahl, Michelle Reed, Cecilia D. Gerstner, Guoxin Ying, Wolfgang Baehr

published 11 Mar 2021

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IL-6 promotes MYC-induced B cell lymphomagenesis independent of STAT3

Oleksi Petrenko, Jinyu Li, Velasco Cimica, Patricio Mena-Taboada, Ha Youn Shin, Stephen D’Amico, Nancy C. Reich

published 02 Mar 2021

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Type 1 dopamine receptor (D1R)-independent circadian food anticipatory activity in mice

Dina R. Assali, Michael Sidikpramana, Andrew P. Villa, Jeffrey Falkenstein, Andrew D. Steele

published 08 Feb 2021

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Differential expression of αVβ3 and αVβ6 integrins in prostate cancer progression

Fabio Quaglia, Shiv Ram Krishn, Yanqing Wang, David W. Goodrich, Peter McCue, Andrew V. Kossenkov, Amy C. Mandigo, Karen E. Knudsen, Paul H. Weinreb, Eva Corey, William K. Kelly, Lucia R. Languino

published 22 Jan 2021

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The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models

Arna Katewa, Eric Suto, Jessica Hui, Jose Heredia, Jie Liang, Jason Hackney, Keith Anderson, Tuija M. Alcantar, Natasha Bacarro, Debra Dunlap, Jeffrey Eastham, Andres Paler-Martinez, Xin Y. Rairdan, Zora Modrusan, Wyne P. Lee, Cary D. Austin, Daniel Lafkas, Nico Ghilardi

published 14 Jan 2021

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Development of an orally-administrable tumor vasculature-targeting therapeutic using annexin A1-binding D-peptides

Motohiro Nonaka, Hideaki Mabashi-Asazuma, Donald L. Jarvis, Kazuhiko Yamasaki, Tomoya O. Akama, Masato Nagaoka, Toshio Sasai, Itsuko Kimura-Takagi, Yoichi Suwa, Takashi Yaegashi, Chun-Teng Huang, Chizuko Nishizawa-Harada, Michiko N. Fukuda

published 06 Jan 2021

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