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Genetically modified animals

Therapeutic Potential of Mesenchymal Stromal Cells and MSC Conditioned Medium in Amyotrophic Lateral Sclerosis (ALS) - In Vitro Evidence from Primary Motor Neuron Cultures, NSC-34 Cells, Astrocytes and Microglia

Hui Sun, Karelle Bénardais, Nancy Stanslowsky, Nadine Thau-Habermann, Niko Hensel, DongYa Huang, Peter Claus, Reinhard Dengler, Martin Stangel, Susanne Petri

published 12 Sep 2013

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Serine Protease HTRA1 Antagonizes Transforming Growth Factor-β Signaling by Cleaving Its Receptors and Loss of HTRA1 In Vivo Enhances Bone Formation

Julie R. Graham, Angela Chamberland, Qingcong Lin, X. Jian Li, David Dai, Weilan Zeng, Mark S. Ryan, Moisés A. Rivera-Bermúdez, Carl R. Flannery, Zhiyong Yang

published 11 Sep 2013

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SPAK Deficiency Corrects Pseudohypoaldosteronism II Caused by WNK4 Mutation

Pei-Yi Chu, Chih-Jen Cheng, Yi-Chang Wu, Yu-Wei Fang, Tom Chau, Shinichi Uchida, Sei Sasaki, Sung-Sen Yang, Shih-Hua Lin

published 11 Sep 2013

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A Small Conductance Calcium-Activated K⁺ Channel in C. elegans, KCNL-2, Plays a Role in the Regulation of the Rate of Egg-Laying

Cavita K. Chotoo, Gary A. Silverman, Daniel C. Devor, Cliff J. Luke

published 10 Sep 2013

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Characterization of Regulatory Dendritic Cells That Mitigate Acute Graft-versus-Host Disease in Older Mice Following Allogeneic Bone Marrow Transplantation

Sabrina M. Scroggins, Alicia K. Olivier, David K. Meyerholz, Annette J. Schlueter

published 10 Sep 2013

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A Wisp3 Cre-knockin Allele Produces Efficient Recombination in Spermatocytes during Early Prophase of Meiosis I

Steven Hann, Laura Kvenvold, Brittney N. Newby, Minh Hong, Matthew L. Warman

published 10 Sep 2013

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Identification of Potential Cytokine Pathways for Therapeutic Intervention in Murine Primary Biliary Cirrhosis

Kazuhito Kawata, Masanobu Tsuda, Guo-Xiang Yang, Weici Zhang, Hajime Tanaka, Koichi Tsuneyama, Patrick Leung, Xiao-Song He, Stuart Knechtle, Aftab A. Ansari, Ross L. Coppel, M. Eric Gershwin

published 10 Sep 2013

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CD146 Deletion in the Nervous System Impairs Appetite, Locomotor Activity and Spatial Learning in Mice

Tao Tu, Qian Gao, Yongting Luo, Jianan Chen, Di Lu, Jing Feng, Dongling Yang, Lina Song, Xiyun Yan

published 10 Sep 2013

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Impaired Cardiac SIRT1 Activity by Carbonyl Stress Contributes to Aging-Related Ischemic Intolerance

Chunhu Gu, Yuan Xing, Li Jiang, Mai Chen, Ming Xu, Yue Yin, Chen Li, Zheng Yang, Lu Yu, Heng Ma

published 10 Sep 2013

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Rap1 GTPase Activation and Barrier Enhancement in RPE Inhibits Choroidal Neovascularization In Vivo

Erika S. Wittchen, Eiichi Nishimura, Manabu McCloskey, Haibo Wang, Lawrence A. Quilliam, Magdalena Chrzanowska-Wodnicka, M. Elizabeth Hartnett

published 10 Sep 2013

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A New Approach for the Study of Lung Smooth Muscle Phenotypes and Its Application in a Murine Model of Allergic Airway Inflammation

Jesus Paez-Cortez, Ramaswamy Krishnan, Anneliese Arno, Linh Aven, Sumati Ram-Mohan, Kruti R. Patel, Jining Lu, Oliver D. King, Xingbin Ai, Alan Fine

published 09 Sep 2013

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A Unique Dermal Dendritic Cell Subset That Skews the Immune Response toward Th2

Ryuichi Murakami, Kaori Denda-Nagai, Shin-ichi Hashimoto, Shigenori Nagai, Masahira Hattori, Tatsuro Irimura

published 09 Sep 2013

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Reduced Number and Morphofunctional Change of Alveolar Macrophages in MafB Gene-Targeted Mice

Michiko Sato-Nishiwaki, Yasuko Aida, Shuichi Abe, Yoko Shibata, Tomomi Kimura, Keiko Yamauchi, Hiroyuki Kishi, Akira Igarashi, Sumito Inoue, Masamichi Sato, Osamu Nakajima, Isao Kubota

published 06 Sep 2013

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