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Genetically modified animals

The Ral Exchange Factor Rgl2 Promotes Cardiomyocyte Survival and Inhibits Cardiac Fibrosis

Rebecca L. Scotland, Leah Allen, Leah J. Hennings, Ginell R. Post, Steven R. Post

published 17 Sep 2013

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AMP Deaminase 3 Deficiency Enhanced 5′-AMP Induction of Hypometabolism

Isadora Susan Daniels, William G. O′Brien III, Vinay Nath, Zhaoyang Zhao, Cheng Chi Lee

published 16 Sep 2013

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Deletion of LRP5 in VLDLR Knockout Mice Inhibits Retinal Neovascularization

Chun-hong Xia, Eric Lu, Jing Zeng, Xiaohua Gong

published 13 Sep 2013

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TRAF6 Is Essential for Maintenance of Regulatory T Cells That Suppress Th2 Type Autoimmunity

Go Muto, Hitoshi Kotani, Taisuke Kondo, Rimpei Morita, Sanae Tsuruta, Takashi Kobayashi, Hervé Luche, Hans Joerg Fehling, Matthew Walsh, Yongwon Choi, Akihiko Yoshimura

published 13 Sep 2013

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Development of Novel ¹²³I-Labeled Pyridyl Benzofuran Derivatives for SPECT Imaging of β-Amyloid Plaques in Alzheimer’s Disease

Masahiro Ono, Yan Cheng, Hiroyuki Kimura, Hiroyuki Watanabe, Kenji Matsumura, Masashi Yoshimura, Shimpei Iikuni, Yoko Okamoto, Masafumi Ihara, Ryosuke Takahashi, Hideo Saji

published 13 Sep 2013

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Inhibition of Fas-Associated Death Domain-Containing Protein (FADD) Protects against Myocardial Ischemia/Reperfusion Injury in a Heart Failure Mouse Model

Qian Fan, Zheng M. Huang, Matthieu Boucher, Xiying Shang, Lin Zuo, Henriette Brinks, Wayne Bond Lau, Jianke Zhang, J. Kurt Chuprun, Erhe Gao

published 13 Sep 2013

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Ketogenic Diet Improves Motor Performance but Not Cognition in Two Mouse Models of Alzheimer’s Pathology

Milene L. Brownlow, Leif Benner, Dominic D’Agostino, Marcia N. Gordon, Dave Morgan

published 12 Sep 2013

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Mu Opioid Receptors on Primary Afferent Nav1.8 Neurons Contribute to Opiate-Induced Analgesia: Insight from Conditional Knockout Mice

Raphaël Weibel, David Reiss, Laurie Karchewski, Olivier Gardon, Audrey Matifas, Dominique Filliol, Jérôme A. J. Becker, John N. Wood, Brigitte L. Kieffer, Claire Gaveriaux-Ruff

published 12 Sep 2013

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Tiam1 Transgenic Mice Display Increased Tumor Invasive and Metastatic Potential of Colorectal Cancer after 1,2-Dimethylhydrazine Treatment

Li-Na Yu, Qing-Ling Zhang, Xin Li, Xing Hua, Yan-Mei Cui, Nian-Jie Zhang, Wen-Ting Liao, Yan-Qing Ding

published 12 Sep 2013

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Therapeutic Potential of Mesenchymal Stromal Cells and MSC Conditioned Medium in Amyotrophic Lateral Sclerosis (ALS) - In Vitro Evidence from Primary Motor Neuron Cultures, NSC-34 Cells, Astrocytes and Microglia

Hui Sun, Karelle Bénardais, Nancy Stanslowsky, Nadine Thau-Habermann, Niko Hensel, DongYa Huang, Peter Claus, Reinhard Dengler, Martin Stangel, Susanne Petri

published 12 Sep 2013

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Serine Protease HTRA1 Antagonizes Transforming Growth Factor-β Signaling by Cleaving Its Receptors and Loss of HTRA1 In Vivo Enhances Bone Formation

Julie R. Graham, Angela Chamberland, Qingcong Lin, X. Jian Li, David Dai, Weilan Zeng, Mark S. Ryan, Moisés A. Rivera-Bermúdez, Carl R. Flannery, Zhiyong Yang

published 11 Sep 2013

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SPAK Deficiency Corrects Pseudohypoaldosteronism II Caused by WNK4 Mutation

Pei-Yi Chu, Chih-Jen Cheng, Yi-Chang Wu, Yu-Wei Fang, Tom Chau, Shinichi Uchida, Sei Sasaki, Sung-Sen Yang, Shih-Hua Lin

published 11 Sep 2013

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A Small Conductance Calcium-Activated K⁺ Channel in C. elegans, KCNL-2, Plays a Role in the Regulation of the Rate of Egg-Laying

Cavita K. Chotoo, Gary A. Silverman, Daniel C. Devor, Cliff J. Luke

published 10 Sep 2013

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