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Genetically modified animals

Usage of Adenovirus Expressing Thymidine Kinase Mediated Hepatocellular Damage for Enabling Mouse Liver Repopulation with Allogenic or Xenogenic Hepatocytes

Daniel Moreno, Anangi Balasiddaiah, Oscar Lamas, Cedric Duret, Leire Neri, Laura Guembe, Miguel Galarraga, Esther Larrea, Martine Daujat-Chavanieu, Jordi Muntane, Patrick Maurel, Jose Ignacio Riezu, Jesus Prieto, Rafael Aldabe

published 24 Sep 2013

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Toll-Like Receptor 2 or Toll-Like Receptor 4 Deficiency Does Not Modify Lupus in MRLlpr Mice

Simon J. Freeley, Angela Giorgini, Calogero Tulone, Reena J. Popat, Catherine Horsfield, Michael G. Robson

published 24 Sep 2013

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Mutant Huntingtin Gene-Dose Impacts on Aggregate Deposition, DARPP32 Expression and Neuroinflammation in HdhQ150 Mice

Douglas Young, Franziska Mayer, Nella Vidotto, Tatjana Schweizer, Ramon Berth, Dorothee Abramowski, Derya R. Shimshek, P. Herman van der Putten, Peter Schmid

published 23 Sep 2013

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High Incidence of HPV-Associated Head and Neck Cancers in FA Deficient Mice Is Associated with E7’s Induction of DNA Damage through Its Inactivation of Pocket Proteins

Jung Wook Park, Myeong-Kyun Shin, Henry C. Pitot, Paul F. Lambert

published 23 Sep 2013

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The Duration of Chlamydia muridarum Genital Tract Infection and Associated Chronic Pathological Changes Are Reduced in IL-17 Knockout Mice but Protection Is Not Increased Further by Immunization

Dean W. Andrew, Melanie Cochrane, Justin H. Schripsema, Kyle H. Ramsey, Samantha J. Dando, Connor P. O’Meara, Peter Timms, Kenneth W. Beagley

published 20 Sep 2013

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T Cell and Dendritic Cell Abnormalities Synergize to Expand Pro-Inflammatory T Cell Subsets Leading to Fatal Autoimmunity in B6.NZBc1 Lupus-Prone Mice

Nafiseh Talaei, Yui-Ho Cheung, Carolina Landolt-Marticorena, Babak Noamani, Timothy Li, Joan E. Wither

published 20 Sep 2013

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Resveratrol Inhibits CD4⁺ T Cell Activation by Enhancing the Expression and Activity of Sirt1

Ting Zou, Yi Yang, Fei Xia, Anfei Huang, Xiaoming Gao, Deyu Fang, Sidong Xiong, Jinping Zhang

published 20 Sep 2013

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Ectopic Expression of Nolz-1 in Neural Progenitors Promotes Cell Cycle Exit/Premature Neuronal Differentiation Accompanying with Abnormal Apoptosis in the Developing Mouse Telencephalon

Sunny Li-Yun Chang, Shih-Yun Chen, Huai-Huei Huang, Hsin-An Ko, Pei-Tsen Liu, Ya-Chi Liu, Ping-Hau Chen, Fu-Chin Liu

published 20 Sep 2013

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Simultaneous Activation of Kras and Inactivation of p53 Induces Soft Tissue Sarcoma and Bladder Urothelial Hyperplasia

Xiaoping Yang, Francisco G. La Rosa, Elizabeth Erin Genova, Kendra Huber, Jerome Schaack, James DeGregori, Natalie J. Serkova, Yuan Li, Lih-Jen Su, Elizabeth Kessler, Thomas W. Flaig

published 18 Sep 2013

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Empathic Fear Responses in Mice Are Triggered by Recognition of a Shared Experience

Jeff Sanders, Mark Mayford, Dilip Jeste

published 18 Sep 2013

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Leucine-Rich α2-Glycoprotein Is a Novel Biomarker of Neurodegenerative Disease in Human Cerebrospinal Fluid and Causes Neurodegeneration in Mouse Cerebral Cortex

Masakazu Miyajima, Madoka Nakajima, Yumiko Motoi, Masao Moriya, Hidenori Sugano, Ikuko Ogino, Eri Nakamura, Norihiro Tada, Miyuki Kunichika, Hajime Arai

published 18 Sep 2013

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Immunization against GAD Induces Antibody Binding to GAD-Independent Antigens and Brainstem GABAergic Neuronal Loss

Thashi Chang, Harry Alexopoulos, Philippa Pettingill, Mary McMenamin, Robert Deacon, Ferenc Erdelyi, Gabor Szabó, Camilla J. Buckley, Angela Vincent

published 18 Sep 2013

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Area-Specific Alterations of Synaptic Plasticity in the 5XFAD Mouse Model of Alzheimer’s Disease: Dissociation between Somatosensory Cortex and Hippocampus

Nadine Crouzin, Kevin Baranger, Mélanie Cavalier, Yannick Marchalant, Catherine Cohen-Solal, François S. Roman, Michel Khrestchatisky, Santiago Rivera, François Féron, Michel Vignes

published 17 Sep 2013

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