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Genetically modified animals

Altered Lipid and Salt Taste Responsivity in Ghrelin and GOAT Null Mice

Huan Cai, Wei-na Cong, Caitlin M. Daimon, Rui Wang, Matthias H. Tschöp, Jean Sévigny, Bronwen Martin, Stuart Maudsley

published 04 Oct 2013

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Development of a Conditional Mesd (Mesoderm Development) Allele for Functional Analysis of the Low-Density Lipoprotein Receptor-Related Family in Defined Tissues

Andrew V. Taibi, Janet K. Lighthouse, Richard C. Grady, Kenneth R. Shroyer, Bernadette C. Holdener

published 04 Oct 2013

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Zfat-Deficiency Results in a Loss of CD3ζ Phosphorylation with Dysregulation of ERK and Egr Activities Leading to Impaired Positive Selection

Masahiro Ogawa, Tadashi Okamura, Shuhei Ishikura, Keiko Doi, Hiroshi Matsuzaki, Yoko Tanaka, Takeharu Ota, Kunihiro Hayakawa, Harumi Suzuki, Toshiyuki Tsunoda, Takehiko Sasazuki, Senji Shirasawa

published 03 Oct 2013

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How Changes in Extracellular Matrix Mechanics and Gene Expression Variability Might Combine to Drive Cancer Progression

Justin Werfel, Silva Krause, Ashley G. Bischof, Robert J. Mannix, Heather Tobin, Yaneer Bar-Yam, Robert M. Bellin, Donald E. Ingber

published 03 Oct 2013

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Suppression of Alzheimer’s Disease-Related Phenotypes by Geranylgeranylacetone in Mice

Tatsuya Hoshino, Koichiro Suzuki, Takahide Matsushima, Naoki Yamakawa, Toshiharu Suzuki, Tohru Mizushima

published 01 Oct 2013

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Creatine Kinase-Overexpression Improves Myocardial Energetics, Contractile Dysfunction and Survival in Murine Doxorubicin Cardiotoxicity

Ashish Gupta, Cory Rohlfsen, Michelle K. Leppo, Vadappuram P. Chacko, Yibin Wang, Charles Steenbergen, Robert G. Weiss

published 01 Oct 2013

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A Constitutively Active Gαi3 Protein Corrects the Abnormal Retinal Pigment Epithelium Phenotype of Oa1−/− mice

Alejandra Young, Ying Wang, Novruz B. Ahmedli, Meisheng Jiang, Debora B. Farber

published 30 Sep 2013

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microRNA-22 Promotes Heart Failure through Coordinate Suppression of PPAR/ERR-Nuclear Hormone Receptor Transcription

Priyatansh Gurha, Tiannan Wang, Ashley H. Larimore, Yassine Sassi, Cei Abreu-Goodger, Maricela O. Ramirez, Anilkumar K. Reddy, Stefan Engelhardt, George E. Taffet, Xander H. T. Wehrens, Mark L. Entman, Antony Rodriguez

published 27 Sep 2013

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Upregulation of Tissue Factor by Activated Stat3 Contributes to Malignant Pleural Effusion Generation via Enhancing Tumor Metastasis and Vascular Permeability in Lung Adenocarcinoma

Hsuan-Heng Yeh, Wen-Tsan Chang, Kuang-Chu Lu, Wu-Wei Lai, Hsiao-Sheng Liu, Wu-Chou Su

published 27 Sep 2013

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Smad2-Dependent Downregulation of miR-30 Is Required for TGF-β-Induced Apoptosis in Podocytes

Shaolin Shi, Liping Yu, Taoran Zhang, Haiying Qi, Sandhya Xavier, Wenjun Ju, Erwin Bottinger

published 26 Sep 2013

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Conditional Deletion of Cytochrome P450 Reductase in Osteoprogenitor Cells Affects Long Bone and Skull Development in Mice Recapitulating Antley-Bixler Syndrome: Role of a Redox Enzyme in Development

Satya P. Panda, Anyonya R. Guntur, Srikanth R. Polusani, Roberto J. Fajardo, Peter T. Gakunga, Linda J. Roman, Bettie Sue Masters

published 25 Sep 2013

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Conditional and Specific Cell Ablation in the Marine Annelid Platynereis dumerilii

Vinoth Babu Veedin-Rajan, Ruth M. Fischer, Florian Raible, Kristin Tessmar-Raible

published 24 Sep 2013

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TRIM3 Regulates the Motility of the Kinesin Motor Protein KIF21B

Dorthe Labonté, Edda Thies, Yvonne Pechmann, Alexander J. Groffen, Matthijs Verhage, August B. Smit, Ronald E. van Kesteren, Matthias Kneussel

published 24 Sep 2013

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