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Genetically modified animals

Perforin and Granzyme B Have Separate and Distinct Roles during Atherosclerotic Plaque Development in Apolipoprotein E Knockout Mice

Paul R. Hiebert, Wendy A. Boivin, Hongyan Zhao, Bruce M. McManus, David J. Granville

published 24 Oct 2013

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Standardized, Systemic Phenotypic Analysis of Umod^C93F and Umod^A227T Mutant Mice

Elisabeth Kemter, Petra Prückl, Birgit Rathkolb, Kateryna Micklich, Thure Adler, Lore Becker, Johannes Beckers, Dirk H. Busch, Alexander A. Götz, Wolfgang Hans, Marion Horsch, Boris Ivandic, Martin Klingenspor, Thomas Klopstock, Jan Rozman, Anja Schrewe, Holger Schulz, Helmut Fuchs, Valérie Gailus-Durner, Martin Hrabé de Angelis, Eckhard Wolf, Bernhard Aigner

published 24 Oct 2013

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Therapeutic Use of a Selective S1P₁ Receptor Modulator Ponesimod in Autoimmune Diabetes

Sylvaine You, Luca Piali, Chantal Kuhn, Beat Steiner, Virginia Sauvaget, Fabrice Valette, Martine Clozel, Jean-François Bach, Lucienne Chatenoud

published 24 Oct 2013

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Normal Development in Mice Over-Expressing the Intracellular Domain of DLL1 Argues against Reverse Signaling by DLL1 In Vivo

Christian Redeker, Karin Schuster-Gossler, Elisabeth Kremmer, Achim Gossler

published 22 Oct 2013

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Quantitative Analysis of α-L-Iduronidase Expression in Immunocompetent Mice Treated with the Sleeping Beauty Transposon System

Elena L. Aronovich, Bryan C. Hall, Jason B. Bell, R. Scott McIvor, Perry B. Hackett

published 21 Oct 2013

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Adult-Specific Systemic Over-Expression Reveals Novel In Vivo Effects of the Soluble Forms of ActRIIA, ActRIIB and BMPRII

Kengo Yamawaki, Shinobu Ueda, Tsutomu Okada, Takeshi Oshima, Makoto Kakitani, Takashi Kato, Kazuma Tomizuka

published 21 Oct 2013

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Aliskiren Attenuates Steatohepatitis and Increases Turnover of Hepatic Fat in Mice Fed with a Methionine and Choline Deficient Diet

Kuei-Chuan Lee, Che-Chang Chan, Ying-Ying Yang, Yun-Cheng Hsieh, Yi-Hsiang Huang, Han-Chieh Lin

published 21 Oct 2013

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Expression and Antimicrobial Function of Beta-Defensin 1 in the Lower Urinary Tract

Brian Becknell, John David Spencer, Ashley R. Carpenter, Xi Chen, Aspinder Singh, Suzanne Ploeger, Jennifer Kline, Patrick Ellsworth, Birong Li, Ehrhardt Proksch, Andrew L. Schwaderer, David S. Hains, Sheryl S. Justice, Kirk M. McHugh

published 21 Oct 2013

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Urea Transporter UT-B Deletion Induces DNA Damage and Apoptosis in Mouse Bladder Urothelium

Zixun Dong, Jianhua Ran, Hong Zhou, Jihui Chen, Tianluo Lei, Weiling Wang, Yi Sun, Guiting Lin, Lise Bankir, Baoxue Yang

published 21 Oct 2013

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Sustained NF-κB Activation and Inhibition in β-Cells Have Minimal Effects on Function and Islet Transplant Outcomes

Aileen J. F. King, Yongjing Guo, Dongsheng Cai, Jennifer Hollister-Lock, Brooke Morris, Alison Salvatori, John A. Corbett, Susan Bonner-Weir, Steven E. Shoelson, Gordon C. Weir

published 18 Oct 2013

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Protein Tyrosine Phosphatase 1B and Insulin Resistance: Role of Endoplasmic Reticulum Stress/Reactive Oxygen Species/Nuclear Factor Kappa B Axis

Evgeniy Panzhinskiy, Jun Ren, Sreejayan Nair

published 18 Oct 2013

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Generation of BAC Transgenic Epithelial Organoids

Gerald Schwank, Amanda Andersson-Rolf, Bon-Kyoung Koo, Nobuo Sasaki, Hans Clevers

published 18 Oct 2013

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Vitamin D₂-Enriched Button Mushroom (Agaricus bisporus) Improves Memory in Both Wild Type and APPswe/PS1dE9 Transgenic Mice

Louise Bennett, Cindy Kersaitis, Stuart Lance Macaulay, Gerald Münch, Garry Niedermayer, Julie Nigro, Matthew Payne, Paul Sheean, Pascal Vallotton, Dimitrios Zabaras, Michael Bird

published 18 Oct 2013

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