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Genetically modified animals

Metabolic differences and differentially expressed genes between C57BL/6J and C57BL/6N mice substrains

Shino Nemoto, Tetsuya Kubota, Hiroshi Ohno

published 22 Dec 2022

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Variant APOL1 protein in plasma associates with larger particles in humans and mouse models of kidney injury

Michael Andrews, Teruhiko Yoshida, Clark M. Henderson, Hannah Pflaum, Ayako McGregor, Joshua A. Lieberman, Ian H. de Boer, Tomas Vaisar, Jonathan Himmelfarb, Bryan Kestenbaum, Joon-Yong Chung, Stephen M. Hewitt, Briana A. Santo, Brandon Ginley, Pinaki Sarder, Avi Z. Rosenberg, Taichi Murakami, Jeffrey B. Kopp, Zsuzsanna Kuklenyik, Andrew N. Hoofnagle

published 24 Oct 2022

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Endothelial derived miRNA-9 mediated cardiac fibrosis in diabetes and its regulation by ZFAS1

Biao Feng, Jieting Liu, Eric Wang, Zhaoliang Su, Subrata Chakrabarti

published 14 Oct 2022

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Selective optogenetic activation of Na_V1.7–expressing afferents in Na_V1.7-ChR2 mice induces nocifensive behavior without affecting responses to mechanical and thermal stimuli

Toyoaki Maruta, Kotaro Hidaka, Satoshi Kouroki, Tomohiro Koshida, Mio Kurogi, Yohko Kage, Seiya Mizuno, Tetsuro Shirasaka, Toshihiko Yanagita, Satoru Takahashi, Ryu Takeya, Isao Tsuneyoshi

published 06 Oct 2022

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HIV-1 Vpr suppresses expression of the thiazide-sensitive sodium chloride co-transporter in the distal convoluted tubule

Shashi Shrivastav, Hewang Lee, Koji Okamoto, Huiyan Lu, Teruhiko Yoshida, Khun Zaw Latt, Hidefumi Wakashin, James L. T. Dalgleish, Erik H. Koritzinsky, Peng Xu, Laureano D. Asico, Joon-Yong Chung, Stephen Hewitt, John J. Gildea, Robin A. Felder, Pedro A. Jose, Avi Z. Rosenberg, Mark A. Knepper, Tomoshige Kino, Jeffrey B. Kopp

published 21 Sep 2022

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Identification of quantitative trait loci for survival in the mutant dynactin p150Glued mouse model of motor neuron disease

Guillermo M. Alexander, Terry D. Heiman-Patterson, Frank Bearoff, Roger B. Sher, Laura Hennessy, Shannon Terek, Nicole Caccavo, Gregory A. Cox, Vivek M. Philip, Elizabeth A. Blankenhorn

published 15 Sep 2022

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Knockout of Trpa1 accelerates age-related cardiac fibrosis and dysfunction

Shuangtao Ma, Donna H. Wang

published 14 Sep 2022

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Fezf2-positive fork cell-like neurons in the mouse insular cortex

Manabu Taniguchi, Misaki Iwahashi, Yuichiro Oka, Sheena Y. X. Tiong, Makoto Sato

published 06 Sep 2022

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Dysregulation of the hippocampal neuronal network by LGI1 auto-antibodies

Elodie Fels, Marie-Eve Mayeur, Estelle Wayere, Clémentine Vincent, Céline Malleval, Jérôme Honnorat, Olivier Pascual

published 19 Aug 2022

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ANRIL regulates multiple molecules of pathogenetic significance in diabetic nephropathy

Parisa Sooshtari, Biao Feng, Saumik Biswas, Michael Levy, Hanxin Lin, Zhaoliang Su, Subrata Chakrabarti

published 19 Aug 2022

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Regulation of rod photoreceptor function by farnesylated G-protein γ-subunits

Alexander V. Kolesnikov, Elena Lobysheva, Jaya P. Gnana-Prakasam, Vladimir J. Kefalov, Oleg G. Kisselev

published 08 Aug 2022

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Gain-of-function, focal segmental glomerulosclerosis Trpc6 mutation minimally affects susceptibility to renal injury in several mouse models

Brittney J. Brown, Kimber L. Boekell, Brian R. Stotter, Brianna E. Talbot, Johannes S. Schlondorff

published 01 Aug 2022

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Aqueous extracts of Urtica dioica (stinging nettle) leaf contain a P2-purinoceptor antagonist—Implications for male fertility

Nicole T. Eise, Jamie S. Simpson, Philip E. Thompson, Sabatino Ventura

published 28 Jul 2022

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