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Genetic engineering

Granzyme A Is Expressed in Mouse Lungs during Mycobacterium tuberculosis Infection but Does Not Contribute to Protection In Vivo

Santiago Uranga, Dessislava Marinova, Carlos Martin, Julián Pardo, Nacho Aguilo

published 07 Apr 2016

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4-1BB Signaling in Conventional T Cells Drives IL-2 Production That Overcomes CD4⁺CD25⁺FoxP3⁺ T Regulatory Cell Suppression

Hampartsoum B. Barsoumian, Esma S. Yolcu, Haval Shirwan

published 06 Apr 2016

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A Modified Integrated Genetic Model for Risk Prediction in Younger Patients with Acute Myeloid Leukemia

Caroline E. Sloan, Marlise R. Luskin, Anne M. Boccuti, Alison R. Sehgal, Jianhua Zhao, Robert D. Daber, Jennifer J. D. Morrissette, Selina M. Luger, Adam Bagg, Phyllis A. Gimotty, Martin Carroll

published 06 Apr 2016

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Mice with a Mutation in the Mdm2 Gene That Interferes with MDM2/Ribosomal Protein Binding Develop a Defect in Erythropoiesis

Takuya Kamio, Bai-wei Gu, Timothy S. Olson, Yanping Zhang, Philip J. Mason, Monica Bessler

published 04 Apr 2016

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Critical Endothelial Regulation by LRP5 during Retinal Vascular Development

Wei Huang, Qing Li, Mahmood Amiry-Moghaddam, Madoka Hokama, Sylvia H. Sardi, Masashi Nagao, Matthew L. Warman, Bjorn R. Olsen

published 31 Mar 2016

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The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington’s Disease Mice

Haiqun Jia, Ying Wang, Charles D. Morris, Vincent Jacques, Joel M. Gottesfeld, James R. Rusche, Elizabeth A. Thomas

published 31 Mar 2016

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Adiponectin at Physiologically Relevant Concentrations Enhances the Vasorelaxative Effect of Acetylcholine via Cav-1/AdipoR-1 Signaling

Yunhui Du, Rui Li, Wayne Bigond Lau, Jianli Zhao, Bernard Lopez, Theodore A. Christopher, Xin-Liang Ma, Yajing Wang

published 29 Mar 2016

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Ezetimibe Promotes Brush Border Membrane-to-Lumen Cholesterol Efflux in the Small Intestine

Takanari Nakano, Ikuo Inoue, Yasuhiro Takenaka, Hiraku Ono, Shigehiro Katayama, Takuya Awata, Takayuki Murakoshi

published 29 Mar 2016

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TCR and IL-7 Signaling Are Altered in the Absence of Functional GTPase of the Immune Associated Nucleotide Binding Protein 5 (GIMAP5)

Xi-Lin Chen, Daniel Serrano, Farnaz Ghobadi, Marian Mayhue, Kasper Hoebe, Subburaj Ilangumaran, Sheela Ramanathan

published 29 Mar 2016

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Overexpression of Poplar PtrWRKY89 in Transgenic Arabidopsis Leads to a Reduction of Disease Resistance by Regulating Defense-Related Genes in Salicylate- and Jasmonate-Dependent Signaling

Yuanzhong Jiang, Li Guo, Rui Liu, Bo Jiao, Xin Zhao, Zhengyi Ling, Keming Luo

published 28 Mar 2016

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The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis

Juliane Braun, Arabella Meixner, Andreas Brachner, Roland Foisner

published 24 Mar 2016

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Long-Chain Omega-3 Polyunsaturated Fatty Acids Have Developmental Effects on the Crop Pest, the Cabbage White Butterfly Pieris rapae

Stefanie M. Hixson, Kruti Shukla, Lesley G. Campbell, Rebecca H. Hallett, Sandy M. Smith, Laurence Packer, Michael T. Arts

published 24 Mar 2016

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Earth Mover’s Distance (EMD): A True Metric for Comparing Biomarker Expression Levels in Cell Populations

Darya Y. Orlova, Noah Zimmerman, Stephen Meehan, Connor Meehan, Jeffrey Waters, Eliver E. B. Ghosn, Alexander Filatenkov, Gleb A. Kolyagin, Yael Gernez, Shanel Tsuda, Wayne Moore, Richard B. Moss, Leonore A. Herzenberg, Guenther Walther

published 23 Mar 2016

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