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Genetic engineering

An Advanced Preclinical Mouse Model for Acute Myeloid Leukemia Using Patients' Cells of Various Genetic Subgroups and In Vivo Bioluminescence Imaging

Binje Vick, Maja Rothenberg, [ ... ], Irmela Jeremias

Pain Inhibition by Optogenetic Activation of Specific Anterior Cingulate Cortical Neurons

Ling Gu, Megan L. Uhelski, [ ... ], Samarendra K. Mohanty

Vitamin D₂-Enriched Button Mushroom (Agaricus bisporus) Improves Memory in Both Wild Type and APPswe/PS1dE9 Transgenic Mice

Louise Bennett, Cindy Kersaitis, [ ... ], Michael Bird

Ultrasound Enhanced Delivery of Molecular Imaging and Therapeutic Agents in Alzheimer's Disease Mouse Models

Scott B. Raymond, Lisa H. Treat, [ ... ], Brian J. Bacskai

Rational and Evolutionary Engineering Approaches Uncover a Small Set of Genetic Changes Efficient for Rapid Xylose Fermentation in Saccharomyces cerevisiae

Soo Rin Kim, Jeffrey M. Skerker, [ ... ], Yong-Su Jin

Ultrasonic Vocalizations Induced by Sex and Amphetamine in M2, M4, M5 Muscarinic and D2 Dopamine Receptor Knockout Mice

Haoran Wang, Shuyin Liang, [ ... ], John Yeomans

Control of Bone Mass and Remodeling by PTH Receptor Signaling in Osteocytes

Charles A. O'Brien, Lilian I. Plotkin, [ ... ], Teresita Bellido

ALS-Associated TDP-43 Induces Endoplasmic Reticulum Stress, Which Drives Cytoplasmic TDP-43 Accumulation and Stress Granule Formation

Adam K. Walker, Kai Y. Soo, [ ... ], Julie D. Atkin

Arabidopsis Fatty Acid Desaturase FAD2 Is Required for Salt Tolerance during Seed Germination and Early Seedling Growth

Jiantao Zhang, Hua Liu, [ ... ], Hongxia Zhang

Efficient Generation of Germ Line Transmitting Chimeras from C57BL/6N ES Cells by Aggregation with Outbred Host Embryos

Marina Gertsenstein, Lauryl M. J. Nutter, [ ... ], Andras Nagy

Cardiomyocyte Aldose Reductase Causes Heart Failure and Impairs Recovery from Ischemia

Ni-Huiping Son, Radha Ananthakrishnan, [ ... ], Ravichandran Ramasamy

Small-Animal PET Imaging of Amyloid-Beta Plaques with [¹¹C]PiB and Its Multi-Modal Validation in an APP/PS1 Mouse Model of Alzheimer's Disease

André Manook, Behrooz H. Yousefi, [ ... ], Alexander Drzezga

Automated High-Content Live Animal Drug Screening Using C. elegans Expressing the Aggregation Prone Serpin α1-antitrypsin Z

Sager J. Gosai, Joon Hyeok Kwak, [ ... ], Stephen C. Pak

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