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Genetic engineering

Cannabinoid receptor 1 positive allosteric modulator ZCZ011 shows differential effects on behavior and the endocannabinoid system in HIV-1 Tat transgenic female and male mice

Barkha J. Yadav-Samudrala, Hailey Dodson, Shreya Ramineni, Elizabeth Kim, Justin L. Poklis, Dai Lu, Bogna M. Ignatowska-Jankowska, Aron H. Lichtman, Sylvia Fitting

published 24 Jun 2024

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Dietary intervention rescues a bone porosity phenotype in a murine model of Neurofibromatosis Type 1 (NF1)

Alexandra K. O’Donohue, Xiaoying C. Li, Lucinda R. Lee, Emily R. Vasiljevski, David G. Little, Craig F. Munns, Aaron Schindeler

published 24 Jun 2024

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Revisiting the NPcis mouse model: A new tool to model plexiform neurofibroma

Camille Plante, Teddy Mohamad, Dhanushka Hewa Bostanthirige, Michel Renaud, Harsimran Sidhu, Michel ElChoueiry, Jean-Paul Sabo Vatasescu, Mikael Poirier, Sameh Geha, Jean-Philippe Brosseau

published 20 Jun 2024

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An oral toxicity assessment of a mosquito larvicidal transgenic algae (Chlamydomonas reinhardtii) using adult Zebrafish and its embryos

Fareeha Amjad, Hamza Khan, Muhammad Islam Khan, Sidra Ayub, Rashid Bhatti, Rabbia Pervaiz, Kausar Malik, Mohsin Ahmad Khan

published 13 Jun 2024

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Malic enzyme 1 knockout has no deleterious phenotype and is favored in the male germline under standard laboratory conditions

Jonathan M. Alektiar, Mengrou Shan, Megan D. Radyk, Li Zhang, Christopher J. Halbrook, Lin Lin, Carlos Espinoza, Ivan F. Mier, Brooke L. Lavoie, Lucie Salvatore, Marina Pasca di Magliano, Lewis C. Cantley, Jacob L. Mueller, Costas A. Lyssiotis

published 06 Jun 2024

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Identifying widespread and recurrent variants of genetic parts to improve annotation of engineered DNA sequences

Matthew J. McGuffie, Jeffrey E. Barrick

published 28 May 2024

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Dach1 is essential for maintaining normal mature podocytes

Keiko Tanaka, Haruko Hayasaka, Taiji Matsusaka

published 28 May 2024

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Persistence of genetically engineered canola populations in the U.S. and the adventitious presence of transgenes in the environment

Steven E. Travers, D. Bryan Bishop, Cynthia L. Sagers

published 22 May 2024

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Pseudopregnant mice generated from Piwil1 deficiency sterile mice

Shuoshuo Xie, Ruixin Qin, Wentao Zeng, Jianmin Li, Yana Lai

published 21 May 2024

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Effects of Nox4 upregulation on PECAM-1 expression in a mouse model of diabetic retinopathy

Jinli Wang, Daniel A. Lai, Joshua J. Wang, Sarah X. Zhang

published 15 May 2024

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Downregulation of SOX9 expression in developing entheses adjacent to intramembranous bone

Asahi Kitamura, Masahito Yamamoto, Hidetomo Hirouchi, Genji Watanabe, Shuichiro Taniguchi, Sayo Sekiya, Satoshi Ishizuka, Juhee Jeong, Kazunari Higa, Shuichiro Yamashita, Shinichi Abe

published 10 May 2024

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The uterine secretome initiates growth of gynecologic tissues in ectopic locations

Jan Sunde, Morgan Wasickanin, Tiffany A. Katz, Laurel Gillette, Sanam Bidadi, Derek O’Neil, Ramya Masand, Richard O. Burney, Kathleen A. Pennington

published 10 May 2024

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Cloning and functional verification of the CmHSP17.9 gene from chrysanthemum

Qin Ling, Shumei Zhang, Xin Li, Beibei Tang, Ai Chen, Tao Zeng, Qiqi Ma, Yijun Chen, Shaokang Tang, Yuanzhi Pan, Qinglin Liu, Yin Jia, Xue Yong, Beibei Jiang

published 08 May 2024

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