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Genetic engineering

Late-stage changes in the composition of cell walls of maize plants expressing an apoplast targeted, senescence enhanced fungal ferulic acid esterase, and the subsequent effects on tissue saccharification

Marcia M. de O. Buanafina, Phillip Morris, Sue Dalton, M. Fernanda Buanafina, Yijuan Wang

published 03 Jan 2025

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Intracerebroventricular administration of a modified hexosaminidase ameliorates late-stage neurodegeneration in a GM2 mouse model

Manuel E. Lopez, Daniel Wendt, Roger Lawrence, Kerui Gong, Hoonsan Ong, Bryan Yip, Joseph Chen, Linley Mangini, Britta Handyside, Alexander Giaramita, Aashish Lamichhane, Melanie Lo, Vishal Agrawal, Jeremy Van Vleet, Amanda Abolhesn, Jessica B. Felix, Isaac Villalpando, Vikas Bhat, Rolando De Angelis, Yuanbin Ru, Ayesha Khan, Sylvia Fong, Terri Christianson, Sherry Bullens, Brett E. Crawford, Stuart Bunting, Mika Aoyagi-Scharber

published 03 Jan 2025

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How French culture influences the framing of genetic modifications on the internet: Insights from Google-based corpus analysis

Anaïs Degache, Séverine Louvel, Stéphanie Abrial, Virginie Tournay

published 23 Dec 2024

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Loss of STAT3 in osteoblasts has detrimental and sexually dimorphic effects on skeletal development

Rebecca K. Davidson, Kylie Corry, Amos Orlofsky, Ping Li, Caleb E. Russell, Amy Zhang, Mariana Moraes de Lima Perini, Carlie N. Priddy, Andrew V. Nguyen, Jiliang Li

published 17 Dec 2024

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Tumorigenicity decrease in Bcl-xL deficient MDCK cells ensuring the safety for influenza vaccine production

Jiahao Zheng, Boran Li, Lanxin Jia, Jiayou Zhang, Zheng Gong, Yang Le, Xuanxuan Nian, Xuedan Li, Bo Liu, Daiguan Yu, Zhegang Zhang, Changgui Li

published 16 Dec 2024

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Effects of genetically modified soybean on physiological variables and gut microbiota of Sprague-Dawley rats

Elham Ashrafi-Dehkordi, Abdolvahab Alborzi, Gholamreza Pouladfar, Seyed Amin Abbasian, Seyed Mohammad Mazloomi

published 12 Dec 2024

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Peroxisomal dysfunction interferes with odontogenesis and leads to developmentally delayed teeth and defects in distinct dental cells in Pex11b-deficient mice

Claudia Colasante, Julia Jednakowski, Klaus-Peter Valerius, Xiaoling Li, Eveline Baumgart-Vogt

published 09 Dec 2024

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Mitochondrial fission is required for thermogenesis in brown adipose tissue

Yuta Ibayashi, Nao Hasuzawa, Seiji Nomura, Masaharu Kabashima, Ayako Nagayama, Shimpei Iwata, Miyuki Kitamura, Kenji Ashida, Yoshinori Moriyama, Ken Yamamoto, Masatoshi Nomura, Lixiang Wang

published 09 Dec 2024

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LARP7 is required for sex chromosome silencing during meiosis in mice

Yukiko Tando, Atsuto Nonomura, Yumi Ito-Matsuoka, Asuka Takehara, Daiji Okamura, Yohei Hayashi, Yasuhisa Matsui

published 05 Dec 2024

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TRPML1 acts as a predisposing factor in lymphedema development by regulating the subcellular localization of aquaporin-3, -5

Lijie Yang, Guanzheng Wang, Yuan Ma, Qiancheng Zhao, He Zhao, Qi Wang, Chonghua Zhong, Chunmei Zhang, Yiming Yang

published 05 Dec 2024

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Comparison of a SARS-CoV-2 mRNA booster immunization containing additional antigens to a spike-based mRNA vaccine against Omicron BA.5 infection in hACE2 mice

Jacklyn R. Hurst, Maedeh Naghibosadat, Patrick Budowski, Jun Liu, Philip Samaan, Frans Budiman, Alexandra Kurtesi, Fredo Qi, Haritha Menon, Rajesh Krishnan, Jumai Abioye, Anne-Claude Gingras, Mario Ostrowski, Natalia Martin Orozco, Robert A. Kozak

published 03 Dec 2024

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White LED intensities during co-cultivation affect the Agrobacterium-mediated soybean (Glycine max) transformation using mature half seeds as explants

Xiaonan Shi, Baochun Li, Marcela Rojas-Pierce, Ricardo Hernández

published 26 Nov 2024

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Single-cell sequencing reveals transcriptional dynamics regulated by ERα in mouse ovaries

Qicai Hu, Yiqian Gui, Congcong Cao, Jun Xie, Huiru Tang

published 21 Nov 2024

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