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Genetic engineering

Enforced Expression of the Transcriptional Coactivator OBF1 Impairs B Cell Differentiation at the Earliest Stage of Development

Alain Bordon, Nabil Bosco, Camille Du Roure, Boris Bartholdy, Hubertus Kohler, Gabriele Matthias, Antonius G. Rolink, Patrick Matthias

published 23 Dec 2008

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BRAF Activation Initiates but Does Not Maintain Invasive Prostate Adenocarcinoma

Joseph H. Jeong, Zhenxiong Wang, Alexander S. Guimaraes, Xuesong Ouyang, Jose L. Figueiredo, Zhihu Ding, Shan Jiang, Isil Guney, Gyeong Hoon Kang, Eyoung Shin, William C. Hahn, Massimo F. Loda, Cory Abate-Shen, Ralph Weissleder, Lynda Chin

published 16 Dec 2008

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Haploinsufficiency of Activation-Induced Deaminase for Antibody Diversification and Chromosome Translocations both In Vitro and In Vivo

Isora V. Sernández, Virginia G. de Yébenes, Yair Dorsett, Almudena R. Ramiro

published 12 Dec 2008

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GPRC6A Null Mice Exhibit Osteopenia, Feminization and Metabolic Syndrome

Min Pi, Ling Chen, Min-Zhao Huang, Wenyu Zhu, Brian Ringhofer, Junming Luo, Lane Christenson, Benyi Li, Jianghong Zhang, P. David Jackson, Pieter Faber, Kurt R. Brunden, John J. Harrington, L. Darryl Quarles

published 03 Dec 2008

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APC Activation Restores Functional CD4⁺CD25⁺ Regulatory T Cells in NOD Mice that Can Prevent Diabetes Development

Jean N. Manirarora, Michele M. Kosiewicz, Sarah A. Parnell, Pascale Alard

published 17 Nov 2008

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Deficiency of FLCN in Mouse Kidney Led to Development of Polycystic Kidneys and Renal Neoplasia

Jindong Chen, Kunihiko Futami, David Petillo, Jun Peng, Pengfei Wang, Jared Knol, Yan Li, Sok-Kean Khoo, Dan Huang, Chao-Nan Qian, Ping Zhao, Karl Dykyma, Racheal Zhang, Brian Cao, Ximing J. Yang, Kyle Furge, Bart O. Williams, Bin Tean Teh

published 30 Oct 2008

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HFR1 Is Crucial for Transcriptome Regulation in the Cryptochrome 1-Mediated Early Response to Blue Light in Arabidopsis thaliana

Xiao-Ning Zhang, Yingjie Wu, John W. Tobias, Brian P. Brunk, Gerald F. Deitzer, Dongmei Liu

published 30 Oct 2008

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OsLIC, a Novel CCCH-Type Zinc Finger Protein with Transcription Activation, Mediates Rice Architecture via Brassinosteroids Signaling

Lei Wang, Yunyuan Xu, Cui Zhang, Qibin Ma, Se-Hwan Joo, Seong-Ki Kim, Zhihong Xu, Kang Chong

published 27 Oct 2008

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Adherent Monomer-Misfolded SOD1

Yasuhiro Watanabe, Eri Morita, Yasuyo Fukada, Koji Doi, Kenichi Yasui, Michio Kitayama, Toshiya Nakano, Kenji Nakashima

published 23 Oct 2008

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Cattle Mammary Bioreactor Generated by a Novel Procedure of Transgenic Cloning for Large-Scale Production of Functional Human Lactoferrin

Penghua Yang, Jianwu Wang, Guochun Gong, Xiuzhu Sun, Ran Zhang, Zhuo Du, Ying Liu, Rong Li, Fangrong Ding, Bo Tang, Yunping Dai, Ning Li

published 20 Oct 2008

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Genetic Disruption of Both Tryptophan Hydroxylase Genes Dramatically Reduces Serotonin and Affects Behavior in Models Sensitive to Antidepressants

Katerina V. Savelieva, Shulei Zhao, Vladimir M. Pogorelov, Indrani Rajan, Qi Yang, Emily Cullinan, Thomas H. Lanthorn

published 15 Oct 2008

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Somatic ‘Soluble’ Adenylyl Cyclase Isoforms Are Unaffected in Sacy^tm1Lex/Sacy^tm1Lex ‘Knockout’ Mice

Jeanne Farrell, Lavoisier Ramos, Martin Tresguerres, Margarita Kamenetsky, Lonny R. Levin, Jochen Buck

published 22 Sep 2008

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Magic-Factor 1, a Partial Agonist of Met, Induces Muscle Hypertrophy by Protecting Myogenic Progenitors from Apoptosis

Marco Cassano, Stefano Biressi, Amanda Finan, Laura Benedetti, Claudia Omes, Renata Boratto, Frank Martin, Marcello Allegretti, Vania Broccoli, Gabriella Cusella De Angelis, Paolo M. Comoglio, Cristina Basilico, Yvan Torrente, Paolo Michieli, Giulio Cossu, Maurilio Sampaolesi

published 16 Sep 2008

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