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Genetic engineering

Genetic Disruption of Both Tryptophan Hydroxylase Genes Dramatically Reduces Serotonin and Affects Behavior in Models Sensitive to Antidepressants

Katerina V. Savelieva, Shulei Zhao, Vladimir M. Pogorelov, Indrani Rajan, Qi Yang, Emily Cullinan, Thomas H. Lanthorn

published 15 Oct 2008

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Somatic ‘Soluble’ Adenylyl Cyclase Isoforms Are Unaffected in Sacy^tm1Lex/Sacy^tm1Lex ‘Knockout’ Mice

Jeanne Farrell, Lavoisier Ramos, Martin Tresguerres, Margarita Kamenetsky, Lonny R. Levin, Jochen Buck

published 22 Sep 2008

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Magic-Factor 1, a Partial Agonist of Met, Induces Muscle Hypertrophy by Protecting Myogenic Progenitors from Apoptosis

Marco Cassano, Stefano Biressi, Amanda Finan, Laura Benedetti, Claudia Omes, Renata Boratto, Frank Martin, Marcello Allegretti, Vania Broccoli, Gabriella Cusella De Angelis, Paolo M. Comoglio, Cristina Basilico, Yvan Torrente, Paolo Michieli, Giulio Cossu, Maurilio Sampaolesi

published 16 Sep 2008

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The Variability of the Harlequin Mouse Phenotype Resembles that of Human Mitochondrial-Complex I-Deficiency Syndromes

Paule Bénit, Sergio Goncalves, Emmanuel Philippe Dassa, Jean-Jacques Brière, Pierre Rustin

published 15 Sep 2008

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Cthrc1 Is a Positive Regulator of Osteoblastic Bone Formation

Hiroaki Kimura, Kin Ming Kwan, Zhaoping Zhang, Jian Min Deng, Bryant G. Darnay, Richard R. Behringer, Takashi Nakamura, Benoit de Crombrugghe, Haruhiko Akiyama

published 09 Sep 2008

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Receptor-Associated Protein (RAP) Plays a Central Role in Modulating Aβ Deposition in APP/PS1 Transgenic Mice

Guilian Xu, Celeste Karch, Ning Li, Nianwei Lin, David Fromholt, Victoria Gonzales, David R. Borchelt

published 08 Sep 2008

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IL-21 Limits Peripheral Lymphocyte Numbers through T Cell Homeostatic Mechanisms

Shrimati Datta, Nora E. Sarvetnick

published 05 Sep 2008

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Transgene-Induced Gene Silencing Is Not Affected by a Change in Ploidy Level

Daniela Pignatta, Brian Dilkes, Tadeusz Wroblewski, Richard W. Michelmore, Luca Comai

published 26 Aug 2008

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Cre-Dependent Expression of Multiple Transgenes in Isolated Neurons of the Adult Forebrain

Sridhara Chakravarthy, Tara Keck, Martijn Roelandse, Robin Hartman, Andreas Jeromin, Sean Perry, Sonja B. Hofer, Thomas Mrsic-Flogel, Christiaan N. Levelt

published 26 Aug 2008

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GABA_A Receptor-Mediated Acceleration of Aging-Associated Memory Decline in APP/PS1 Mice and Its Pharmacological Treatment by Picrotoxin

Yuji Yoshiike, Tetsuya Kimura, Shunji Yamashita, Hiroyuki Furudate, Tatsuya Mizoroki, Miyuki Murayama, Akihiko Takashima

published 21 Aug 2008

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Origin of Co-Expression Patterns in E.coli and S.cerevisiae Emerging from Reverse Engineering Algorithms

Mattia Zampieri, Nicola Soranzo, Daniele Bianchini, Claudio Altafini

published 20 Aug 2008

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Agrobacterium-Mediated Transformation of Tomato Elicits Unexpected Flower Phenotypes with Similar Gene Expression Profiles

Yi-Hong Wang, Michael A. Campbell

published 13 Aug 2008

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Control of Bone Mass and Remodeling by PTH Receptor Signaling in Osteocytes

Charles A. O'Brien, Lilian I. Plotkin, Carlo Galli, Joseph J. Goellner, Arancha R. Gortazar, Matthew R. Allen, Alexander G. Robling, Mary Bouxsein, Ernestina Schipani, Charles H. Turner, Robert L. Jilka, Robert S. Weinstein, Stavros C. Manolagas, Teresita Bellido

published 13 Aug 2008

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