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Genetic engineering

Identification of the Transgenic Integration Site in Immunodeficient tgε26 Human CD3ε Transgenic Mice

Izumi Ohigashi, Yuki Yamasaki, Tsukasa Hirashima, Yousuke Takahama

published 22 Dec 2010

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AAV Vector-Mediated Overexpression of CB1 Cannabinoid Receptor in Pyramidal Neurons of the Hippocampus Protects against Seizure-Induced Excitoxicity

Stephan Guggenhuber, Krisztina Monory, Beat Lutz, Matthias Klugmann

published 21 Dec 2010

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A Novel Statistical Algorithm for Gene Expression Analysis Helps Differentiate Pregnane X Receptor-Dependent and Independent Mechanisms of Toxicity

M. Ann Mongan, Robert T. Dunn II, Steven Vonderfecht, Nancy Everds, Guang Chen, Cheng Su, Marnie Higgins-Garn, Yuan Chen, Cynthia A. Afshari, Toni L. Williamson, Linda Carlock, Christopher DiPalma, Suzanne Moss, Jeanine Bussiere, Charles Qualls Jr., Yudong D. He, Hisham K. Hamadeh

published 21 Dec 2010

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The Nuclear Inclusion a (NIa) Protease of Turnip Mosaic Virus (TuMV) Cleaves Amyloid-β

Hye-Eun Han, Saravanan Sellamuthu, Bae Hyun Shin, Yong Jae Lee, Sungmin Song, Ji-Seon Seo, In-Sun Baek, Jeomil Bae, Hannah Kim, Yung Joon Yoo, Yong-Keun Jung, Woo Keun Song, Pyung-Lim Han, Woo Jin Park

published 20 Dec 2010

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Differential Contribution of Rod and Cone Circadian Clocks in Driving Retinal Melatonin Rhythms in Xenopus

Naoto Hayasaka, Silvia I. LaRue, Carla B. Green

published 20 Dec 2010

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Marginal Level Dystrophin Expression Improves Clinical Outcome in a Strain of Dystrophin/Utrophin Double Knockout Mice

Dejia Li, Yongping Yue, Dongsheng Duan

published 20 Dec 2010

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Lithium Improves Hippocampal Neurogenesis, Neuropathology and Cognitive Functions in APP Mutant Mice

Anna Fiorentini, Maria Cristina Rosi, Cristina Grossi, Ilaria Luccarini, Fiorella Casamenti

published 20 Dec 2010

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Zinc Overload Enhances APP Cleavage and Aβ Deposition in the Alzheimer Mouse Brain

Chun-Yan Wang, Tao Wang, Wei Zheng, Bao-Lu Zhao, Gorm Danscher, Yu-Hua Chen, Zhan-You Wang

published 17 Dec 2010

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A Method for Generation of Bone Marrow-Derived Macrophages from Cryopreserved Mouse Bone Marrow Cells

Fernanda M. Marim, Tatiana N. Silveira, Djalma S. Lima Jr., Dario S. Zamboni

published 17 Dec 2010

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MicroRNA-Related Cofilin Abnormality in Alzheimer's Disease

Jiaqi Yao, Tom Hennessey, Alex Flynt, Eric Lai, M. Flint Beal, Michael T. Lin

published 16 Dec 2010

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A Transient Transgenic RNAi Strategy for Rapid Characterization of Gene Function during Embryonic Development

Bryan C. Bjork, Yuko Fujiwara, Shannon W. Davis, Haiyan Qiu, Thomas L. Saunders, Peter Sandy, Stuart Orkin, Sally A. Camper, David R. Beier

published 16 Dec 2010

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Galanin Receptor 1 Deletion Exacerbates Hippocampal Neuronal Loss after Systemic Kainate Administration in Mice

P. Elyse Schauwecker

published 13 Dec 2010

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Fiber Type Conversion by PGC-1α Activates Lysosomal and Autophagosomal Biogenesis in Both Unaffected and Pompe Skeletal Muscle

Shoichi Takikita, Cynthia Schreiner, Rebecca Baum, Tao Xie, Evelyn Ralston, Paul H. Plotz, Nina Raben

published 13 Dec 2010

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