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Genetic engineering

Resistance to MPTP-Neurotoxicity in α-Synuclein Knockout Mice Is Complemented by Human α-Synuclein and Associated with Increased β-Synuclein and Akt Activation

Bobby Thomas, Allen S. Mandir, Neva West, Ying Liu, Shaida A. Andrabi, Wanda Stirling, Valina L. Dawson, Ted M. Dawson, Michael K. Lee

published 31 Jan 2011

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Experience-Dependent Plasticity and Modulation of Growth Regulatory Molecules at Central Synapses

Simona Foscarin, Danilo Ponchione, Ermira Pajaj, Ketty Leto, Maciej Gawlak, Grzegorz M. Wilczynski, Ferdinando Rossi, Daniela Carulli

published 31 Jan 2011

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Resveratrol Inhibits Pancreatic Cancer Stem Cell Characteristics in Human and Kras^G12D Transgenic Mice by Inhibiting Pluripotency Maintaining Factors and Epithelial-Mesenchymal Transition

Sharmila Shankar, Dara Nall, Su-Ni Tang, Daniel Meeker, Jenna Passarini, Jay Sharma, Rakesh K. Srivastava

published 31 Jan 2011

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Activation of the Canonical Wnt/β-Catenin Pathway in ATF3-Induced Mammary Tumors

Leqin Yan, Luis Della Coletta, K. Leslie Powell, Jianjun Shen, Howard Thames, C. Marcelo Aldaz, Michael C. MacLeod

published 31 Jan 2011

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Orally Administrated Cinnamon Extract Reduces β-Amyloid Oligomerization and Corrects Cognitive Impairment in Alzheimer's Disease Animal Models

Anat Frydman-Marom, Aviad Levin, Dorit Farfara, Tali Benromano, Roni Scherzer-Attali, Sivan Peled, Robert Vassar, Daniel Segal, Ehud Gazit, Dan Frenkel, Michael Ovadia

published 28 Jan 2011

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Interaction of TGFβ and BMP Signaling Pathways during Chondrogenesis

Bettina Keller, Tao Yang, Yuqing Chen, Elda Munivez, Terry Bertin, Bernhard Zabel, Brendan Lee

published 28 Jan 2011

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The Influence of Chronic Cerebral Hypoperfusion on Cognitive Function and Amyloid β Metabolism in APP Overexpressing Mice

Mahito Yamada, Masafumi Ihara, Yoko Okamoto, Takakuni Maki, Kazuo Washida, Akihiro Kitamura, Yoshiki Hase, Hidefumi Ito, Keizo Takao, Tsuyoshi Miyakawa, Raj N. Kalaria, Hidekazu Tomimoto, Ryosuke Takahashi

published 27 Jan 2011

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The Thioredoxin TRX-1 Modulates the Function of the Insulin-Like Neuropeptide DAF-28 during Dauer Formation in Caenorhabditis elegans

Juan Carlos Fierro-González, Astrid Cornils, Joy Alcedo, Antonio Miranda-Vizuete, Peter Swoboda

published 27 Jan 2011

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Induction of the Wnt Antagonist Dickkopf-1 Is Involved in Stress-Induced Hippocampal Damage

Francesco Matrisciano, Carla L. Busceti, Domenico Bucci, Rosamaria Orlando, Alessandra Caruso, Gemma Molinaro, Irene Cappuccio, Barbara Riozzi, Roberto Gradini, Marta Motolese, Filippo Caraci, Agata Copani, Sergio Scaccianoce, Daniela Melchiorri, Valeria Bruno, Giuseppe Battaglia, Ferdinando Nicoletti

published 27 Jan 2011

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Delaying Gal4-Driven Gene Expression in the Zebrafish with Morpholinos and Gal80

Adèle Faucherre, Hernán López-Schier

published 26 Jan 2011

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Programmable Ligand Detection System in Plants through a Synthetic Signal Transduction Pathway

Mauricio S. Antunes, Kevin J. Morey, J. Jeff Smith, Kirk D. Albrecht, Tessa A. Bowen, Jeffrey K. Zdunek, Jared F. Troupe, Matthew J. Cuneo, Colleen T. Webb, Homme W. Hellinga, June I. Medford

published 25 Jan 2011

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Transgenic Biofortification of the Starchy Staple Cassava (Manihot esculenta) Generates a Novel Sink for Protein

Mohammad Abhary, Dimuth Siritunga, Gene Stevens, Nigel J. Taylor, Claude M. Fauquet

published 25 Jan 2011

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Long Tract of Untranslated CAG Repeats Is Deleterious in Transgenic Mice

Ren-Jun Hsu, Kuang-Ming Hsiao, Min-Jon Lin, Chui-Yen Li, Li-Chun Wang, Luen-Kui Chen, Huichin Pan

published 21 Jan 2011

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