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Genetic engineering

Eliosin-an alternative product from the HmPKD1 locus is a component of endoplasmic reticulum mitochondria membrane contact sites

Almira Kurbegovic, Virginie Lazar, Wei-Min Xu, Maya Seshan, John S. Underwood, Radmila Micanovic, Jeremy M. Pomerantz, Rajneesh Srivastava, Sarath Janga, Emma H. Doud, Sherry Clendenon, Marie Trudel, Angela Wandinger-Ness, Robert L. Bacallao

published 30 Oct 2025

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Volumetric MRI of dorsal root ganglia as a biomarker for disease progression and response to AAV treatment in a mouse model of Fabry disease

Fuqiang Zhao, Shipeng Yuan, Charalambos Kaittanis, Mugdha Deshpande, Abirami Kugadas, Katayoun Derakhchan, Wanida Ruangsiriluk, Rizwana Islam, Natalia Boukharov, Paul McQuade, Johannes Tauscher, Christopher T. Winkelmann, Talakad G. Lohith

published 24 Oct 2025

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GMO approvals under pressure: How climate shocks shape policy across nations

Xiangwen Kong

published 22 Oct 2025

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Functional connectivity patterns of the Giant Toad Rhinella horribilis in anthropogenically modified landscapes

Gerardo J. Soria-Ortiz, Leticia M. Ochoa-Ochoa, Juan P. Jaramillo-Correa, Íñigo Martínez-Solano, Ella Vázquez-Domínguez

published 15 Oct 2025

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Caveolin-1 knockout improves CFA-induced inflammatory pain in adult mice through modulating the cGAS STING pathway and autophagy

Huan Chang, Cancan Cheng, Ning Zheng, Haiyan Zhu, Hui Yang, Xiaocheng Zhu, Fan Zhang

published 09 Oct 2025

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Post-pleistocene colonisation rather than the contemporary environment has most influenced the current population structure of Scottish Atlantic salmon (Salmo salar)

Finn Cowell, Oscar E. Gaggiotti, Eef Cauwelier

published 01 Oct 2025

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Gene electrotransfer with flow-through microchannel and lower alternating voltage generated induced pluripotent cells from human lymphoblastoid cell lines

Miho Ishii-Teshima, Koki Maeda, Kazuki Hanauchi, Emika Asechi, Defan Setyawan, Takeshi Niki, Kenji Nakashima, Hirofumi Kurita, Rika Numano, Takayuki Shibata

published 26 Sep 2025

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Liver-specific glucagon dysfunction promotes PP-cell hyperplasia and formation of glucagon and PP double-positive cells

Yuko Nakagawa, Takuro Horii, Ayako Fukunaka, Takashi Sato, Zhehao Zhang, Masaki Kobayashi, Tadahiro Kitamura, Yoshitaka Hayashi, Takashi Nishimura, Izuho Hatada, Yoshio Fujitani

published 23 Sep 2025

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Exploratory trajectory inference reveals convergent lineages for CD8 T cells in chronic LCMV infection

Jan T. Schleicher, Revant Gupta, Dario Cerletti, Ioana Sandu, Annette Oxenius, Manfred Claassen

published 19 Sep 2025

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ACE1 does not influence cerebral Aβ degradation or amyloid plaque accumulation in 5XFAD mice

Sohee Jeon, Alia O. Alia, Jelena Popovic, Robert Vassar, Leah K. Cuddy

published 15 Sep 2025

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Transient vascular occlusions in a zebrafish model of mycobacterial brain infection

Megan I. Hayes, Sumedha Ravishankar, Tariq Qayum, Victor Nizet, Cressida A. Madigan

published 12 Sep 2025

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Genome-wide identiffcation of the WRKY gene family in poplar and the positive role of PsnWRKY95 in response to cadmium stress

Yuzhao Ma, Yiqi Liu, Fenglin Jia, Wanying Zhu, Guoyue Wang, Xiaojin Yang, Qing Guo, Hongbo Zhang

published 12 Sep 2025

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Reversing metabolic dysregulation in farnesoid X receptor knockout mice via gut microbiota modulation

Ines Leila Paraiso, Armando Alcázar Magaña, Alexandra Alexiev, Thomas J. Sharpton, Claudia S. Maier, Chrissa Kioussi, Jan F. Stevens

published 05 Sep 2025

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