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Genetic engineering

Post-pleistocene colonisation rather than the contemporary environment has most influenced the current population structure of Scottish Atlantic salmon (Salmo salar)

Finn Cowell, Oscar E. Gaggiotti, Eef Cauwelier

published 01 Oct 2025

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Gene electrotransfer with flow-through microchannel and lower alternating voltage generated induced pluripotent cells from human lymphoblastoid cell lines

Miho Ishii-Teshima, Koki Maeda, Kazuki Hanauchi, Emika Asechi, Defan Setyawan, Takeshi Niki, Kenji Nakashima, Hirofumi Kurita, Rika Numano, Takayuki Shibata

published 26 Sep 2025

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Liver-specific glucagon dysfunction promotes PP-cell hyperplasia and formation of glucagon and PP double-positive cells

Yuko Nakagawa, Takuro Horii, Ayako Fukunaka, Takashi Sato, Zhehao Zhang, Masaki Kobayashi, Tadahiro Kitamura, Yoshitaka Hayashi, Takashi Nishimura, Izuho Hatada, Yoshio Fujitani

published 23 Sep 2025

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Exploratory trajectory inference reveals convergent lineages for CD8 T cells in chronic LCMV infection

Jan T. Schleicher, Revant Gupta, Dario Cerletti, Ioana Sandu, Annette Oxenius, Manfred Claassen

published 19 Sep 2025

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ACE1 does not influence cerebral Aβ degradation or amyloid plaque accumulation in 5XFAD mice

Sohee Jeon, Alia O. Alia, Jelena Popovic, Robert Vassar, Leah K. Cuddy

published 15 Sep 2025

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Transient vascular occlusions in a zebrafish model of mycobacterial brain infection

Megan I. Hayes, Sumedha Ravishankar, Tariq Qayum, Victor Nizet, Cressida A. Madigan

published 12 Sep 2025

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Genome-wide identiffcation of the WRKY gene family in poplar and the positive role of PsnWRKY95 in response to cadmium stress

Yuzhao Ma, Yiqi Liu, Fenglin Jia, Wanying Zhu, Guoyue Wang, Xiaojin Yang, Qing Guo, Hongbo Zhang

published 12 Sep 2025

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Reversing metabolic dysregulation in farnesoid X receptor knockout mice via gut microbiota modulation

Ines Leila Paraiso, Armando Alcázar Magaña, Alexandra Alexiev, Thomas J. Sharpton, Claudia S. Maier, Chrissa Kioussi, Jan F. Stevens

published 05 Sep 2025

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Transgenic mice overexpressing Pitx2 in the atria develop tachycardia-bradycardia syndrome

Shunsuke Baba, Satoko Shinjo, Daiki Seya, Hiroki Bochimoto, Toru Akaike, Atsushi Nakano, Susumu Minamisawa

published 04 Sep 2025

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Do organisms need an impact factor? Citations of key biological resources including model organisms reveal usage patterns and impact

Agata Piekniewska, Martijn Roelandse, Kevin C. Kent Lloyd, Ian Korf, Stephen Randal Voss, Giovanni de Castro, Diogo M. Magnani, Zoltan Varga, Christina James-Zorn, Marko Horb, Jeffery S. Grethe, Anita Bandrowski

published 13 Aug 2025

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Establishing a non-viral transfection system for fibroblasts using branched polyethylenimine

Tim Lukas Lübbersmeyer, Kirsten Wissel, Andrea Hoffmann, Lisa Kötter, Thomas Lenarz, Gerrit Paasche

published 05 Aug 2025

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Partial FAM19A5 deficiency in mice leads to disrupted spine maturation, hyperactivity, and an altered fear response

Anu Shahapal, Sumi Park, Sangjin Yoo, Shi-Xun Ma, Jongha Lee, Hoyun Kwak, Jong-Ik Hwang, Jae Young Seong

published 05 Aug 2025

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Peripheral administration of blood from tau transgenic animals exacerbates brain tau-associated pathology

Laura Vegas-Gomez, Matias Pizarro, Jesus Garcia-Martin, Maria Angeles Arredondo-Alcala, Bianca Bustamante, Carolina Gonzalez-Silva, Soledad Matus, Rodrigo Diaz-Espinoza, Antonia Gutierrez, Rodrigo Morales, Claudia Duran-Aniotz, Ines Moreno-Gonzalez

published 15 Jul 2025

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