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Genetic engineering

Tau-Targeted Immunization Impedes Progression of Neurofibrillary Histopathology in Aged P301L Tau Transgenic Mice

Mian Bi, Arne Ittner, [ ... ], Lars M. Ittner

Onset and Progression of Behavioral and Molecular Phenotypes in a Novel Congenic R6/2 Line Exhibiting Intergenerational CAG Repeat Stability

Randi-Michelle Cowin, Nghiem Bui, [ ... ], Richard Paylor

Role of NADPH Oxidase versus Neutrophil Proteases in Antimicrobial Host Defense

R. Robert Vethanayagam, Nikolaos G. Almyroudis, [ ... ], Brahm H. Segal

Redistribution of DAT/α-Synuclein Complexes Visualized by “In Situ” Proximity Ligation Assay in Transgenic Mice Modelling Early Parkinson's Disease

Arianna Bellucci, Laura Navarria, [ ... ], PierFranco Spano

Modulation of Thyroid Hormone-Dependent Gene Expression in Xenopus laevis by INhibitor of Growth (ING) Proteins

Caren C. Helbing, Mary J. Wagner, [ ... ], Leon W. Browder

miRNA Expression Profiling of the Murine TH-MYCN Neuroblastoma Model Reveals Similarities with Human Tumors and Identifies Novel Candidate MiRNAs

Marta Terrile, Kenneth Bryan, [ ... ], Raymond L. Stallings

Constitutive MAP Kinase Activation in Hematopoietic Stem Cells Induces a Myeloproliferative Disorder

Eva Chung, Chia-Lin Hsu, Motonari Kondo

ProSAAS-Derived Peptides are Colocalized with Neuropeptide Y and Function as Neuropeptides in the Regulation of Food Intake

Jonathan H. Wardman, Iryna Berezniuk, [ ... ], Lloyd D. Fricker

Transient mTOR Inhibition Facilitates Continuous Growth of Liver Tumors by Modulating the Maintenance of CD133+ Cell Populations

Zhaojuan Yang, Li Zhang, [ ... ], Yongzhong Liu

Post-Transcriptional Silencing of Flavonol Synthase mRNA in Tobacco Leads to Fruits with Arrested Seed Set

Monika Mahajan, Paramvir Singh Ahuja, Sudesh Kumar Yadav

Characterization of PTZ-Induced Seizure Susceptibility in a Down Syndrome Mouse Model That Overexpresses CSTB

Véronique Brault, Benoît Martin, [ ... ], Yann Hérault

Inducible Gene Manipulations in Brain Serotonergic Neurons of Transgenic Rats

Tillmann Weber, Kai Schönig, Björn Tews, Dusan Bartsch

Increased Expression of PS1 Is Sufficient to Elevate the Level and Activity of γ-Secretase In Vivo

Tong Li, Yue-Ming Li, [ ... ], Philip C. Wong

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