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Genetic engineering

Preventing Phosphorylation of Sterol Regulatory Element-Binding Protein 1a by MAP-Kinases Protects Mice from Fatty Liver and Visceral Obesity

Jorg Kotzka, Birgit Knebel, [ ... ], Dirk Muller–Wieland

Skeletal Muscle PGC-1α Is Required for Maintaining an Acute LPS-Induced TNFα Response

Jesper Olesen, Signe Larsson, [ ... ], Henriette Pilegaard

Effect of the Citrus Lycopene β-Cyclase Transgene on Carotenoid Metabolism in Transgenic Tomato Fruits

Fei Guo, Wenjing Zhou, [ ... ], Xiuxin Deng

FoxO1 Gain of Function in the Pancreas Causes Glucose Intolerance, Polycystic Pancreas, and Islet Hypervascularization

Osamu Kikuchi, Masaki Kobayashi, [ ... ], Tadahiro Kitamura

Genetic Ablation of Pannexin1 Protects Retinal Neurons from Ischemic Injury

Galina Dvoriantchikova, Dmitry Ivanov, [ ... ], Valery I. Shestopalov

Liver-Specific Expression of Transcriptionally Active SREBP-1c Is Associated with Fatty Liver and Increased Visceral Fat Mass

Birgit Knebel, Jutta Haas, [ ... ], Jorg Kotzka

Cellular Prion Protein Expression Is Not Regulated by the Alzheimer's Amyloid Precursor Protein Intracellular Domain

Victoria Lewis, Isobel J. Whitehouse, [ ... ], Nigel M. Hooper

Antagonistic Actions of HLH/bHLH Proteins Are Involved in Grain Length and Weight in Rice

Dany Heang, Hidenori Sassa

Mutant TDP-43 and FUS Cause Age-Dependent Paralysis and Neurodegeneration in C. elegans

Alexandra Vaccaro, Arnaud Tauffenberger, [ ... ], J. Alex Parker

TSC1/2 Signaling Complex Is Essential for Peripheral Naïve CD8⁺ T Cell Survival and Homeostasis in Mice

Lianjun Zhang, Hongbing Zhang, [ ... ], Yong Zhao

Comparison of Phenotypes between Different vangl2 Mutants Demonstrates Dominant Effects of the Looptail Mutation during Hair Cell Development

Haifeng Yin, Catherine O. Copley, Lisa V. Goodrich, Michael R. Deans

The Effects of Apolipoprotein F Deficiency on High Density Lipoprotein Cholesterol Metabolism in Mice

William R. Lagor, David W. Fields, [ ... ], Daniel J. Rader

RHGF-2 Is an Essential Rho-1 Specific RhoGEF that binds to the Multi-PDZ Domain Scaffold Protein MPZ-1 in Caenorhabditis elegans

Li Lin, Thuy Tran, [ ... ], Robert M. Steven

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